| The N terminus of monoamine transporters is a lever required for the action of amphetamines S Sucic, S Dallinger, B Zdrazil, R Weissensteiner, TN Jørgensen, M Holy, ... Journal of Biological Chemistry 285 (14), 10924-10938, 2010 | 155 | 2010 |
| The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C S Sucic, A El-Kasaby, O Kudlacek, S Sarker, HH Sitte, P Marin, ... Journal of Biological Chemistry 286 (18), 16482-16490, 2011 | 111 | 2011 |
| STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior E Kong, S Sucic, FJ Monje, SN Reisinger, G Savalli, W Diao, D Khan, ... Scientific reports 5 (1), 9009, 2015 | 105 | 2015 |
| The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter S Sarker, R Weissensteiner, I Steiner, HH Sitte, GF Ecker, M Freissmuth, ... Molecular pharmacology 78 (6), 1026-1035, 2010 | 85 | 2010 |
| Ca2+/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome T Steinkellner, JW Yang, TR Montgomery, WQ Chen, MT Winkler, S Sucic, ... Journal of Biological Chemistry 287 (35), 29627-29635, 2012 | 76 | 2012 |
| Big Lessons from Tiny Flies: Drosophila melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems AS Kasture, T Hummel, S Sucic, M Freissmuth International Journal of Molecular Sciences 19 (6), 1788, 2018 | 70 | 2018 |
| The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization S Brast, A Grabner, S Sucic, HH Sitte, E Hermann, H Pavenstädt, ... FASEB journal: official publication of the Federation of American Societies …, 2012 | 68 | 2012 |
| Switching the clientele S Sucic, F Koban, A El-Kasaby, O Kudlacek, T Stockner, HH Sitte, ... Journal of Biological Chemistry 288 (8), 5330-5341, 2013 | 61 | 2013 |
| A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter F Koban, A El-Kasaby, C Häusler, T Stockner, BM Simbrunner, HH Sitte, ... Journal of Biological Chemistry 290 (21), 13263-13278, 2015 | 48 | 2015 |
| A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter A El-Kasaby, F Koban, HH Sitte, M Freissmuth, S Sucic Journal of Biological Chemistry 289 (42), 28987-29000, 2014 | 48 | 2014 |
| Ligand selectivity among the dopamine and serotonin transporters specified by the forward binding reaction PS Hasenhuetl, K Schicker, X Koenig, Y Li, S Sarker, T Stockner, S Sucic, ... Molecular Pharmacology 88 (1), 12-18, 2015 | 44 | 2015 |
| First trimester pregnancy decidual natural killer cells contain and spontaneously release high quantities of granulysin DV Vujaklija, T Gulic, S Sucic, K Nagata, K Ogawa, G Laskarin, S Saito, ... American journal of reproductive immunology 66 (5), 363-372, 2011 | 44 | 2011 |
| Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism HMM Asjad, A Kasture, A El-Kasaby, M Sackel, T Hummel, M Freissmuth, ... Journal of Biological Chemistry 292 (47), 19250-19265, 2017 | 43 | 2017 |
| Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones*♦ A Kasture, A El-Kasaby, D Szöllősi, HMM Asjad, A Grimm, T Stockner, ... Journal of Biological Chemistry 291 (40), 20876-20890, 2016 | 41 | 2016 |
| Functional and biochemical consequences of disease variants in neurotransmitter transporters: a special emphasis on folding and trafficking deficits S Bhat, A El-Kasaby, M Freissmuth, S Sucic Pharmacology & therapeutics 222, 107785, 2021 | 36 | 2021 |
| Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome A El-Kasaby, A Kasture, F Koban, M Hotka, HMM Asjad, H Kubista, ... Neuropharmacology 161, 107572, 2019 | 36 | 2019 |
| Comparison of the β-adrenergic receptor antagonists landiolol and esmolol: receptor selectivity, partial agonism, and pharmacochaperoning actions S Nasrollahi-Shirazi, S Sucic, Q Yang, M Freissmuth, C Nanoff Journal of Pharmacology and Experimental Therapeutics 359 (1), 73-81, 2016 | 33 | 2016 |
| Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates S Bhat, PS Hasenhuetl, A Kasture, A El-Kasaby, MH Baumann, ... Journal of Biological Chemistry 292 (40), 16773-16786, 2017 | 32 | 2017 |
| SLC6 transporter folding diseases and pharmacochaperoning M Freissmuth, T Stockner, S Sucic Targeting Trafficking in Drug Development, 249-270, 2018 | 31 | 2018 |
| Nanopharmacological force sensing to reveal allosteric coupling in transporter binding sites R Zhu, D Sinwel, PS Hasenhuetl, K Saha, V Kumar, P Zhang, C Rankl, ... Angewandte Chemie 128 (5), 1751-1754, 2016 | 31 | 2016 |
Michael FreissmuthMedical University of ViennaBestätigte E-Mail-Adresse bei meduniwien.ac.at
