Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5 S Sekine, Y Kanamaru, M Koike, A Nishihara, M Okada, H Kinoshita, ... Journal of Biological Chemistry 287 (41), 34635-34645, 2012 | 181 | 2012 |
Stress-activated MAP kinase cascades in cellular senescence J Maruyama, I Naguro, K Takeda, H Ichijo Current medicinal chemistry 16 (10), 1229-1235, 2009 | 108 | 2009 |
ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney I Naguro, T Umeda, Y Kobayashi, J Maruyama, K Hattori, Y Shimizu, ... Nature communications 3 (1), 1285, 2012 | 85 | 2012 |
Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model Z Yang, K Nakagawa, A Sarkar, J Maruyama, H Iwasa, Y Bao, ... Molecular and cellular biology 34 (9), 1607-1621, 2014 | 60 | 2014 |
A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells M Kodaka, Z Yang, K Nakagawa, J Maruyama, X Xu, A Sarkar, A Ichimura, ... Experimental cell research 336 (2), 171-181, 2015 | 51 | 2015 |
The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein H Iwasa, T Kudo, S Maimaiti, M Ikeda, J Maruyama, K Nakagawa, Y Hata Journal of Biological Chemistry 288 (42), 30320-30329, 2013 | 51 | 2013 |
Discovery of a small molecule to increase cardiomyocytes and protect the heart after ischemic injury H Hara, N Takeda, M Kondo, M Kubota, T Saito, J Maruyama, T Fujiwara, ... JACC: Basic to Translational Science 3 (5), 639-653, 2018 | 50 | 2018 |
A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits … S Kawano, J Maruyama, S Nagashima, K Inami, W Qiu, H Iwasa, ... The journal of biochemistry 158 (5), 413-423, 2015 | 30 | 2015 |
Novel YAP1 activator, identified by transcription-based functional screen, limits multiple myeloma growth J Maruyama, K Inami, F Michishita, X Jiang, H Iwasa, K Nakagawa, ... Molecular Cancer Research 16 (2), 197-211, 2018 | 29 | 2018 |
Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway J Maruyama, Y Kobayashi, T Umeda, A Vandewalle, K Takeda, H Ichijo, ... Scientific reports 6 (1), 18710, 2016 | 21 | 2016 |
The RASSF6 tumor suppressor protein regulates apoptosis and cell cycle progression via retinoblastoma protein S Hossain, H Iwasa, A Sarkar, J Maruyama, K Arimoto-Matsuzaki, Y Hata Molecular and Cellular Biology, 2018 | 15 | 2018 |
BCL‐XL binds and antagonizes RASSF 6 tumor suppressor to suppress p53 expression X Xu, H Iwasa, S Hossain, A Sarkar, J Maruyama, K Arimoto‐Matsuzaki, ... Genes to Cells 22 (12), 993-1003, 2017 | 12 | 2017 |
Domain analysis of Ras‐association domain family member 6 upon interaction with MDM 2 A Sarkar, H Iwasa, S Hossain, X Xu, T Sawada, T Shimizu, J Maruyama, ... FEBS letters 591 (2), 260-272, 2017 | 12 | 2017 |
CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells S Nagashima, J Maruyama, K Honda, Y Kondoh, H Osada, M Nawa, ... Journal of Biological Chemistry 297 (1), 2021 | 11 | 2021 |
Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin N Noguchi, Y Kondo, N Maeda, S Higa-Nakamine, S Toku, J Maruyama, ... Archives of biochemistry and biophysics 529 (2), 75-85, 2013 | 11 | 2013 |
The RAS-interacting chaperone UNC119 drives the RASSF6–MDM2–p53 axis and antagonizes RAS-mediated malignant transformation T Shimizu, T Nakamura, H Inaba, H Iwasa, J Maruyama, ... Journal of Biological Chemistry 295 (32), 11214-11230, 2020 | 8 | 2020 |
Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability Y Lu, J Maruyama, K Kuwata, H Fukuda, H Iwasa, K Arimoto-Matsuzaki, ... Biochemistry and Biophysics Reports 16, 130, 2018 | 6 | 2018 |
Validation of chemical compound library screening for transcriptional co‐activator with PDZ‐binding motif inhibitors using GFP‐fused transcriptional co‐activator with PDZ … S Nagashima, J Maruyama, S Kawano, H Iwasa, K Nakagawa, ... Cancer Science 107 (6), 791-802, 2016 | 6 | 2016 |
UNC 119 is a binding partner of tumor suppressor Ras‐association domain family 6 and induces apoptosis and cell cycle arrest by MDM 2 and p53 H Iwasa, A Sarkar, T Shimizu, T Sawada, S Hossain, X Xu, J Maruyama, ... Cancer Science 109 (9), 2767-2780, 2018 | 5 | 2018 |
Protein kinase Cα activation switches YAP1 from TEAD‐mediated signaling to p73‐mediated signaling CK Sinclear, J Maruyama, S Nagashima, K Arimoto‐Matsuzaki, ... Cancer Science 113 (4), 1305-1320, 2022 | 4 | 2022 |