Tanja Mittag
Title
Cited by
Cited by
Year
Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization
A Molliex, J Temirov, J Lee, M Coughlin, AP Kanagaraj, HJ Kim, T Mittag, ...
Cell 163 (1), 123-133, 2015
12792015
Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
7072018
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
S Alberti, A Gladfelter, T Mittag
Cell 176 (3), 419-434, 2019
5762019
Atomic-level characterization of disordered protein ensembles
T Mittag, JD Forman-Kay
Current opinion in structural biology 17 (1), 3-14, 2007
4352007
Protein dynamics and conformational disorder in molecular recognition
T Mittag, LE Kay, JD Forman‐Kay
Journal of Molecular Recognition: An Interdisciplinary Journal 23 (2), 105-116, 2010
4082010
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
3302017
Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
T Mittag, S Orlicky, WY Choy, X Tang, H Lin, F Sicheri, LE Kay, M Tyers, ...
Proceedings of the National Academy of Sciences 105 (46), 17772-17777, 2008
3042008
Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase
T Mittag, J Marsh, A Grishaev, S Orlicky, H Lin, F Sicheri, M Tyers, ...
Structure 18 (4), 494-506, 2010
2442010
Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity
M Borg, T Mittag, T Pawson, M Tyers, JD Forman-Kay, HS Chan
Proceedings of the National Academy of Sciences 104 (23), 9650-9655, 2007
2182007
Conformational switches modulate protein interactions in peptide antibiotic synthetases
A Koglin, MR Mofid, F Löhr, B Schäfer, VV Rogov, MM Blum, T Mittag, ...
Science 312 (5771), 273-276, 2006
1872006
From sequence and forces to structure, function, and evolution of intrinsically disordered proteins
JD Forman-Kay, T Mittag
Structure 21 (9), 1492-1499, 2013
1792013
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
EW Martin, AS Holehouse, I Peran, M Farag, JJ Incicco, A Bremer, ...
Science 367 (6478), 694-699, 2020
1622020
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ...
The EMBO journal 37 (5), e97452, 2018
1472018
Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation
EW Martin, AS Holehouse, CR Grace, A Hughes, RV Pappu, T Mittag
Journal of the American Chemical Society 138 (47), 15323-15335, 2016
1352016
G3BP1 is a tunable switch that triggers phase separation to assemble stress granules
P Yang, C Mathieu, RM Kolaitis, P Zhang, J Messing, U Yurtsever, Z Yang, ...
Cell 181 (2), 325-345. e28, 2020
1312020
Relationship of Sequence and Phase Separation in Protein Low-Complexity Regions
EW Martin, T Mittag
Biochemistry 57 (17), 2478-2487, 2018
1252018
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
JJ Bouchard, JH Otero, DC Scott, E Szulc, EW Martin, N Sabri, D Granata, ...
Molecular Cell 72 (1), 19-36, 2018
1242018
Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
MR Marzahn, S Marada, J Lee, A Nourse, S Kenrick, H Zhao, ...
The EMBO journal 35 (12), 1254-1275, 2016
1032016
Multiple modes of protein–protein interactions promote RNP granule assembly
T Mittag, R Parker
Journal of molecular biology 430 (23), 4636-4649, 2018
882018
Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface
DM Duda, JL Olszewski, AE Tron, M Hammel, LJ Lambert, MB Waddell, ...
Molecular cell 47 (3), 371-382, 2012
612012
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