| α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ... Science 313 (5785), 324-328, 2006 | 1341 | 2006 |
| Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS HJ Kim, NC Kim, YD Wang, EA Scarborough, J Moore, Z Diaz, ... Nature 495 (7442), 467-473, 2013 | 1015 | 2013 |
| Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ... Nature 466 (7310), 1069-1075, 2010 | 997 | 2010 |
| Stress granules as crucibles of ALS pathogenesis YR Li, OD King, J Shorter, AD Gitler Journal of cell biology 201 (3), 361-372, 2013 | 654 | 2013 |
| Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 650 | 2015 |
| TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler Journal of Biological Chemistry 284 (30), 20329-20339, 2009 | 611 | 2009 |
| The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis AD Gitler, BJ Bevis, J Shorter, KE Strathearn, S Hamamichi, LJ Su, ... Proceedings of the National Academy of Sciences 105 (1), 145-150, 2008 | 510 | 2008 |
| The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease OD King, AD Gitler, J Shorter Brain research 1462, 61-80, 2012 | 506 | 2012 |
| α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity AD Gitler, A Chesi, ML Geddie, KE Strathearn, S Hamamichi, KJ Hill, ... Nature genetics 41 (3), 308-315, 2009 | 504 | 2009 |
| Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ... Nature neuroscience 18 (9), 1226-1229, 2015 | 414 | 2015 |
| A suite of Gateway® cloning vectors for high‐throughput genetic analysis in Saccharomyces cerevisiae S Alberti, AD Gitler, S Lindquist Yeast 24 (10), 913-919, 2007 | 408 | 2007 |
| A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity BS Johnson, JM McCaffery, S Lindquist, AD Gitler Proceedings of the National Academy of Sciences 105 (17), 6439-6444, 2008 | 394 | 2008 |
| Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS Z Sun, Z Diaz, X Fang, MP Hart, A Chesi, J Shorter, AD Gitler PLoS biol 9 (4), e1000614, 2011 | 385 | 2011 |
| Semaphorin-plexin signaling guides patterning of the developing vasculature J Torres-Vázquez, AD Gitler, SD Fraser, JD Berk, VN Pham, MC Fishman, ... Developmental cell 7 (1), 117-123, 2004 | 378 | 2004 |
| A yeast functional screen predicts new candidate ALS disease genes J Couthouis, MP Hart, J Shorter, M DeJesus-Hernandez, R Erion, ... Proceedings of the National Academy of Sciences 108 (52), 20881-20890, 2011 | 352 | 2011 |
| PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development AD Gitler, MM Lu, JA Epstein Developmental cell 7 (1), 107-116, 2004 | 346 | 2004 |
| Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop H Kook, JJ Lepore, AD Gitler, MM Lu, WWM Yung, J Mackay, R Zhou, ... The Journal of clinical investigation 112 (6), 863-871, 2003 | 330 | 2003 |
| Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity E Yeger-Lotem, L Riva, LJ Su, AD Gitler, AG Cashikar, OD King, ... Nature genetics 41 (3), 316-323, 2009 | 298 | 2009 |
| Prion-like disorders: blurring the divide between transmissibility and infectivity M Cushman, BS Johnson, OD King, AD Gitler, J Shorter Journal of cell science 123 (8), 1191-1201, 2010 | 290 | 2010 |
| Local RNA translation at the synapse and in disease L Liu-Yesucevitz, GJ Bassell, AD Gitler, AC Hart, E Klann, JD Richter, ... Journal of Neuroscience 31 (45), 16086-16093, 2011 | 288 | 2011 |
