Aaron D. Gitler
Aaron D. Gitler
Professor of Genetics, Stanford University
Verified email at stanford.edu
TitleCited byYear
α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ...
Science 313 (5785), 324-328, 2006
12212006
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ...
Nature 466 (7310), 1069, 2010
8442010
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
HJ Kim, NC Kim, YD Wang, EA Scarborough, J Moore, Z Diaz, ...
Nature 495 (7442), 467, 2013
8012013
Stress granules as crucibles of ALS pathogenesis
YR Li, OD King, J Shorter, AD Gitler
J Cell Biol 201 (3), 361-372, 2013
5272013
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler
Journal of Biological Chemistry 284 (30), 20329-20339, 2009
5152009
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ...
Science 347 (6229), 1436-1441, 2015
5092015
α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
AD Gitler, A Chesi, ML Geddie, KE Strathearn, S Hamamichi, KJ Hill, ...
Nature genetics 41 (3), 308, 2009
4752009
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
AD Gitler, BJ Bevis, J Shorter, KE Strathearn, S Hamamichi, LJ Su, ...
Proceedings of the National Academy of Sciences 105 (1), 145-150, 2008
4522008
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
OD King, AD Gitler, J Shorter
Brain research 1462, 61-80, 2012
4192012
Semaphorin-plexin signaling guides patterning of the developing vasculature
J Torres-Vázquez, AD Gitler, SD Fraser, JD Berk, VN Pham, MC Fishman, ...
Developmental cell 7 (1), 117-123, 2004
3702004
A suite of Gateway® cloning vectors for high‐throughput genetic analysis in Saccharomyces cerevisiae
S Alberti, AD Gitler, S Lindquist
Yeast 24 (10), 913-919, 2007
3632007
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
BS Johnson, JM McCaffery, S Lindquist, AD Gitler
Proceedings of the National Academy of Sciences 105 (17), 6439-6444, 2008
3612008
PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development
AD Gitler, MM Lu, JA Epstein
Developmental cell 7 (1), 107-116, 2004
3302004
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ...
Nature neuroscience 18 (9), 1226, 2015
3232015
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS
Z Sun, Z Diaz, X Fang, MP Hart, A Chesi, J Shorter, AD Gitler
PLoS biology 9 (4), e1000614, 2011
3192011
Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop
H Kook, JJ Lepore, AD Gitler, MM Lu, WWM Yung, J Mackay, R Zhou, ...
The Journal of clinical investigation 112 (6), 863-871, 2003
3162003
A yeast functional screen predicts new candidate ALS disease genes
J Couthouis, MP Hart, J Shorter, M DeJesus-Hernandez, R Erion, ...
Proceedings of the National Academy of Sciences 108 (52), 20881-20890, 2011
2982011
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity
E Yeger-Lotem, L Riva, LJ Su, AD Gitler, AG Cashikar, OD King, ...
Nature genetics 41 (3), 316, 2009
2712009
Hop is an unusual homeobox gene that modulates cardiac development
F Chen, H Kook, R Milewski, AD Gitler, MM Lu, J Li, R Nazarian, ...
Cell 110 (6), 713-723, 2002
2692002
Local RNA translation at the synapse and in disease
L Liu-Yesucevitz, GJ Bassell, AD Gitler, AC Hart, E Klann, JD Richter, ...
Journal of Neuroscience 31 (45), 16086-16093, 2011
2622011
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Articles 1–20