| Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting. MK Sinha, I Opentanova, JP Ohannesian, JW Kolaczynski, ML Heiman, ... The Journal of clinical investigation 98 (6), 1277-1282, 1996 | 835 | 1996 |
| [Lys (B28), Pro (B29)]-human insulin: a rapidly absorbed analogue of human insulin DC Howey, RR Bowsher, RL Brunelle, JR Woodworth Diabetes 43 (3), 396-402, 1994 | 730 | 1994 |
| Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective JWA Findlay, WC Smith, JW Lee, GD Nordblom, I Das, BS DeSilva, ... Journal of pharmaceutical and biomedical analysis 21 (6), 1249-1273, 2000 | 680 | 2000 |
| Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products G Shankar, V Devanarayan, L Amaravadi, YC Barrett, R Bowsher, ... Journal of pharmaceutical and biomedical analysis 48 (5), 1267-1281, 2008 | 596 | 2008 |
| Serum leptin levels in women with anorexia nervosa S Grinspoon, T Gulick, H Askari, M Landt, K Lee, E Anderson, Z Ma, ... The Journal of Clinical Endocrinology & Metabolism 81 (11), 3861-3863, 1996 | 571 | 1996 |
| Metabolic and immunologic effects of insulin lispro in gestational diabetes. L Jovanovic, S Ilic, DJ Pettitt, K Hugo, M Gutierrez, RR Bowsher, ... Diabetes care 22 (9), 1422-1427, 1999 | 330 | 1999 |
| Report of the American Diabetes Association's Task Force on standardization of the insulin assay DC Robbins, L Andersen, R Bowsher, R Chance, B Dinesen, B Frank, ... Diabetes 45 (2), 242-256, 1996 | 248 | 1996 |
| Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: a conference report JW Lee, RS Weiner, JM Sailstad, RR Bowsher, DW Knuth, PJ O’Brien, ... Pharmaceutical research 22, 499-511, 2005 | 206 | 2005 |
| Biosynthetic human proinsulin: review of chemistry, in vitro and in vivo receptor binding, animal and human pharmacology studies, and clinical trial experience JA Galloway, SA Hooper, CT Spradlin, DC Howey, BH Frank, ... Diabetes Care 15 (5), 666-692, 1992 | 204 | 1992 |
| Standardization of insulin immunoassays: report of the American Diabetes Association Workgroup S Marcovina, RR Bowsher, WG Miller, M Staten, G Myers, SP Caudill, ... Clinical chemistry 53 (4), 711-716, 2007 | 176 | 2007 |
| Relationship of proinsulin and insulin to cardiovascular risk factors in nondiabetic subjects SM Haffner, L Mykkänen, MP Stern, RA Valdez, JA Heisserman, ... Diabetes 42 (9), 1297-1302, 1993 | 176 | 1993 |
| Development, validation, and implementation of a multiplex immunoassay for the simultaneous determination of five cytokines in human serum CA Ray, RR Bowsher, WC Smith, V Devanarayan, MB Willey, JT Brandt, ... Journal of pharmaceutical and biomedical analysis 36 (5), 1037-1044, 2005 | 162 | 2005 |
| Measurement of insulin-like growth factor-II in physiological fluids and tissues. I. An improved extraction procedure and radioimmunoassay for human and rat fluids RR BOWSHER, WEIHUA LEE, JM APATHY, PJ O’BRIEN, AL FERGUSON, ... Endocrinology 128 (2), 805-814, 1991 | 148 | 1991 |
| A new radioenzymatic assay for histamine using purified histamine N-methyltransferase KM Verburg, RR Bowsher, DP Henry Life sciences 32 (25), 2855-2867, 1983 | 128 | 1983 |
| Rat histamine N-methyltransferase. Quantification, tissue distribution, purification, and immunologic properties. RR Bowsher, KM Verburg, DP Henry Journal of Biological Chemistry 258 (20), 12215-12220, 1983 | 123 | 1983 |
| Disproportionately increased proinsulin levels are associated with the insulin resistance syndrome SM Haffner, L Mykkänen, RA Valdez, MP Stern, DL Holloway, ... The Journal of Clinical Endocrinology & Metabolism 79 (6), 1806-1810, 1994 | 119 | 1994 |
| A preponderance of small dense LDL is associated with specific insulin, proinsulin and the components of the insulin resistance syndrome in non-diabetic subjects SM Haffner, L Mykkänen, D Robbins, R Valdez, H Miettinen, BV Howard, ... Diabetologia 38, 1328-1336, 1995 | 114 | 1995 |
| Bioanalytical method validation for macromolecules in support of pharmacokinetic studies JM Smolec, B DeSilva, W Smith, R Weiner, M Kelly, B Lee, M Khan, ... Pharmaceutical research 22, 1425-1431, 2005 | 111 | 2005 |
| Proinsulin and specific insulin concentration in high-and low-risk populations for NIDDM SM Haffner, RR Bowsher, L Mykkänen, HP Hazuda, BD Mitchell, ... Diabetes 43 (12), 1490-1493, 1994 | 111 | 1994 |
| Hyperglycemia in extremely-low-birth-weight infants W Meetze, R Bowsher, J Compton, H Moorehead Neonatology 74 (3), 214-221, 1998 | 110 | 1998 |
