Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies J Zhang, D Dutta, A Köttgen, A Tin, P Schlosser, ME Grams, B Harvey, ... Nature Genetics 54 (5), 593-602, 2022 | 214 | 2022 |
Discovery and prioritization of variants and genes for kidney function in> 1.2 million individuals KJ Stanzick, Y Li, P Schlosser, M Gorski, M Wuttke, LF Thomas, ... Nature Communications 12 (1), 4350, 2021 | 192 | 2021 |
Epigenome-wide association studies identify DNA methylation associated with kidney function AY Chu*, A Tin*, P Schlosser*, YA Ko, C Qiu, C Yao, R Joehanes, ... Nature communications 8 (1), 1286, 2017 | 178 | 2017 |
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans P Schlosser*, Y Li*, P Sekula*, J Raffler, F Grundner-Culemann, ... Nature genetics 52 (2), 167-176, 2020 | 119 | 2020 |
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation N Blagitko-Dorfs*, P Schlosser*, G Greve*, D Pfeifer, R Meier, A Baude, ... Leukemia 33 (4), 945-956, 2019 | 94 | 2019 |
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy K Kiryluk, E Sanchez-Rodriguez, XJ Zhou, F Zanoni, L Liu, N Mladkova, ... Nature genetics 55 (7), 1091-1105, 2023 | 80 | 2023 |
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases M Wielscher, PR Mandaviya, B Kuehnel, R Joehanes, R Mustafa, ... Nature communications 13 (1), 2408, 2022 | 52 | 2022 |
Genome-wide association studies of metabolites in patients with CKD identify multiple loci and illuminate tubular transport mechanisms Y Li, P Sekula, M Wuttke, J Wahrheit, B Hausknecht, UT Schultheiss, ... Journal of the American Society of Nephrology 29 (5), 1513-1524, 2018 | 50 | 2018 |
Meta-analyses identify DNA methylation associated with kidney function and damage P Schlosser*✉, A Tin*, PR Matias-Garcia, CHL Thio, R Joehanes, H Liu, ... Nature communications 12 (1), 7174, 2021 | 44 | 2021 |
Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life KA Walker, J Chen, L Shi, Y Yang, M Fornage, L Zhou, P Schlosser, ... Science translational medicine 15 (705), eadf5681, 2023 | 42 | 2023 |
The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study C Ziegler, F Grundner-Culemann, MA Schiele, P Schlosser, L Kollert, ... Translational psychiatry 9 (1), 314, 2019 | 42 | 2019 |
Proteins associated with risk of kidney function decline in the general population ME Grams, A Surapaneni, J Chen, L Zhou, Z Yu, D Dutta, PA Welling, ... Journal of the American Society of Nephrology 32 (9), 2291-2302, 2021 | 41 | 2021 |
Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine P Schlosser*✉, N Scherer*, F Grundner-Culemann, S Monteiro-Martins, ... Nature genetics, 1-14, 2023 | 33 | 2023 |
Urine metabolite levels, adverse kidney outcomes, and mortality in CKD patients: a metabolome-wide association study I Steinbrenner, UT Schultheiss, F Kotsis, P Schlosser, H Stockmann, ... American Journal of Kidney Diseases 78 (5), 669-677. e1, 2021 | 32 | 2021 |
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism Y Cheng, P Schlosser, J Hertel, P Sekula, PJ Oefner, U Spiekerkoetter, ... Nature communications 12 (1), 964, 2021 | 32 | 2021 |
Plasma proteomics of renal function: a transethnic meta-analysis and mendelian randomization study PR Matías-García, R Wilson, Q Guo, SB Zaghlool, JM Eales, X Xu, ... Journal of the American Society of Nephrology 32 (7), 1747-1763, 2021 | 31 | 2021 |
Integration of GWAS summary statistics and gene expression reveals target cell types underlying kidney function traits Y Li, S Haug, P Schlosser, A Teumer, A Tin, C Pattaro, A Köttgen, ... Journal of the American Society of Nephrology 31 (10), 2326-2340, 2020 | 30 | 2020 |
NAT8 variants, N-acetylated amino acids, and progression of CKD S Luo, A Surapaneni, Z Zheng, EP Rhee, J Coresh, AM Hung, ... Clinical Journal of the American Society of Nephrology 16 (1), 37-47, 2021 | 29 | 2021 |
Discovery of potential serum and urine-based microRNA as minimally-invasive biomarkers for breast and gynecological cancer A Ritter, M Hirschfeld, K Berner, M Jaeger, F Grundner-Culemann, ... Cancer Biomarkers 27 (2), 225-242, 2020 | 29 | 2020 |
Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension S Luo, EV Feofanova, A Tin, S Tung, EP Rhee, J Coresh, DE Arking, ... Kidney international 100 (2), 430-439, 2021 | 28 | 2021 |