Lubka Roumenina
Lubka Roumenina
INSERM UMRS1138, InC2 Lab Inflammation, Complement and Cancer
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Cited by
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Complement system part I–molecular mechanisms of activation and regulation
NS Merle, SE Church, V Fremeaux-Bacchi, LT Roumenina
Frontiers in immunology 6, 262, 2015
Complement system part II: role in immunity
NS Merle, R Noe, L Halbwachs-Mecarelli, V Fremeaux-Bacchi, ...
Frontiers in immunology 6, 257, 2015
Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
A Servais, LH Noel, LT Roumenina, M Le Quintrec, S Ngo, ...
Kidney international 82 (4), 454-464, 2012
Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations
F Fakhouri, L Roumenina, F Provot, M Sallée, S Caillard, L Couzi, M Essig, ...
Journal of the American Society of Nephrology 21 (5), 859-867, 2010
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes”(KDIGO) Controversies Conference
THJ Goodship, HT Cook, F Fakhouri, FC Fervenza, V Frémeaux-Bacchi, ...
Kidney international 91 (3), 539-551, 2017
Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
J Zuber, F Fakhouri, LT Roumenina, C Loirat, V Frémeaux-Bacchi
Nature Reviews Nephrology 8 (11), 643-657, 2012
Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort
JE Salmon, C Heuser, M Triebwasser, MK Liszewski, D Kavanagh, ...
PLoS medicine 8 (3), e1001013, 2011
Complement factor H related proteins (CFHRs)
C Skerka, Q Chen, V Fremeaux-Bacchi, LT Roumenina
Molecular immunology 56 (3), 170-180, 2013
Complement alternative pathway acts as a positive feedback amplification of neutrophil activation
L Camous, L Roumenina, S Bigot, S Brachemi, V Frémeaux-Bacchi, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1340-1349, 2011
C1q and its growing family
R Ghai, P Waters, LT Roumenina, M Gadjeva, MS Kojouharova, ...
Immunobiology 212 (4-5), 253-266, 2007
Endothelium structure and function in kidney health and disease
N Jourde-Chiche, F Fakhouri, L Dou, J Bellien, S Burtey, M Frimat, ...
Nature Reviews Nephrology 15 (2), 87-108, 2019
Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome
M Frimat, F Tabarin, JD Dimitrov, C Poitou, L Halbwachs-Mecarelli, ...
Blood, The Journal of the American Society of Hematology 122 (2), 282-292, 2013
Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome
LT Roumenina, M Jablonski, C Hue, J Blouin, JD Dimitrov, ...
Blood, The Journal of the American Society of Hematology 114 (13), 2837-2845, 2009
Alternative complement pathway assessment in patients with atypical HUS
LT Roumenina, C Loirat, MA Dragon-Durey, L Halbwachs-Mecarelli, ...
Journal of immunological methods 365 (1-2), 8-26, 2011
Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains
LT Roumenina, MM Ruseva, A Zlatarova, R Ghai, M Kolev, N Olova, ...
Biochemistry 45 (13), 4093-4104, 2006
Context-dependent roles of complement in cancer
LT Roumenina, MV Daugan, F Petitprez, C Sautès-Fridman, WH Fridman
Nature Reviews Cancer 19 (12), 698-715, 2019
A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function
LT Roumenina, M Frimat, EC Miller, F Provot, MA Dragon-Durey, ...
Blood, The Journal of the American Society of Hematology 119 (18), 4182-4191, 2012
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles
NS Merle, A Grunenwald, H Rajaratnam, V Gnemmi, M Frimat, ...
JCI insight 3 (12), 2018
Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome
EC Schramm, LT Roumenina, T Rybkine, S Chauvet, P Vieira-Martins, ...
Blood, The Journal of the American Society of Hematology 125 (15), 2359-2369, 2015
Heme: modulator of plasma systems in hemolytic diseases
LT Roumenina, J Rayes, S Lacroix-Desmazes, JD Dimitrov
Trends in Molecular Medicine 22 (3), 200-213, 2016
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