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Xiaojing Yang
Xiaojing Yang
Scientist, Zymo Research Corporation
Bestätigte E-Mail-Adresse bei zymoresearch.com
Titel
Zitiert von
Zitiert von
Jahr
Gene body methylation can alter gene expression and is a therapeutic target in cancer
X Yang, H Han, DD De Carvalho, FD Lay, PA Jones, G Liang
Cancer cell 26 (4), 577-590, 2014
11172014
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
J Tan, X Yang, L Zhuang, X Jiang, W Chen, PL Lee, RKM Karuturi, ...
Genes & development 21 (9), 1050-1063, 2007
10272007
Targeting DNA methylation for epigenetic therapy
X Yang, F Lay, H Han, PA Jones
Trends in pharmacological sciences 31 (11), 536-546, 2010
3802010
DNA Methylation Screening Identifies Driver Epigenetic Events of Cancer Cell Survival
DD De Carvalho, S Sharma, JS You, SF Su, PC Taberlay, TK Kelly, ...
Cancer Cell 21 (5), 655-667, 2012
3252012
miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb–E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
X Yang, M Feng, X Jiang, Z Wu, Z Li, M Aau, Q Yu
Genes & development 23 (20), 2388-2393, 2009
2812009
DACT3 is an epigenetic regulator of Wnt/β-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications
X Jiang, J Tan, J Li, S Kivimäe, X Yang, L Zhuang, PL Lee, MTW Chan, ...
Cancer cell 13 (6), 529-541, 2008
2792008
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter
H Han, CC Cortez, X Yang, PW Nichols, PA Jones, G Liang
Human molecular genetics 20 (22), 4299-4310, 2011
2492011
Loss of epigenetic information as a cause of mammalian aging
JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ...
Cell 186 (2), 305-326. e27, 2023
2292023
CDKN1C (p57KIP2) Is a Direct Target of EZH2 and Suppressed by Multiple Epigenetic Mechanisms in Breast Cancer Cells
X Yang, RKM Karuturi, F Sun, M Aau, K Yu, R Shao, LD Miller, PBO Tan, ...
PloS one 4 (4), e5011, 2009
1992009
DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells
CE Duymich, J Charlet, X Yang, PA Jones, G Liang
Nature communications 7 (1), 11453, 2016
1312016
Allelic methylation levels of the non-coding VTRNA2-1 located on chromosome 5q31. 1 predict outcome in AML.
MB Treppendahl, X Qiu, A Søgaard, X Yang, C Nandrup-Bus, C Hother, ...
Blood, 2011
1152011
Myc/miR-378/TOB2/cyclin D1 functional module regulates oncogenic transformation
M Feng, Z Li, M Aau, CH Wong, X Yang, Q Yu
Oncogene 30 (19), 2242-2251, 2011
1002011
Functional DNA demethylation is accompanied by chromatin accessibility
K Pandiyan, JS You, X Yang, C Dai, XJ Zhou, SB Baylin, PA Jones, ...
Nucleic Acids Research, 2013
952013
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells
F Sun, E Chan, Z Wu, X Yang, VE Marquez, Q Yu
Molecular cancer therapeutics 8 (12), 3191-3202, 2009
912009
Gene Reactivation by 5-Aza-2′-Deoxycytidine–Induced Demethylation Requires SRCAP–Mediated H2A. Z Insertion to Establish Nucleosome Depleted Regions
X Yang, H Noushmehr, H Han, C Andreu-Vieyra, G Liang, PA Jones
PLoS Genetics 8 (3), e1002604, 2012
812012
Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress
J Li, J Tan, L Zhuang, B Banerjee, X Yang, JFL Chau, PL Lee, MP Hande, ...
Cancer Research 67 (23), 11317-11326, 2007
752007
A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium
W Sun, T Triche Jr, J Malvar, P Gaynon, R Sposto, X Yang, H Bittencourt, ...
Blood, The Journal of the American Society of Hematology 131 (10), 1145-1148, 2018
622018
Synergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cells
H Han, X Yang, K Pandiyan, G Liang
PLoS One 8 (9), e75136, 2013
542013
Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s disease
E Coninx, YC Chew, X Yang, W Guo, A Coolkens, S Baatout, L Moons, ...
Aging (Albany NY) 12 (20), 20817, 2020
262020
Integrative epigenome analysis identifies a Polycomb-targeted differentiation program as a tumor-suppressor event epigenetically inactivated in colorectal cancer
J Tan, X Yang, X Jiang, J Zhou, Z Li, PL Lee, B Li, P Robson, Q Yu
Cell death & disease 5 (7), e1324-e1324, 2014
202014
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