| The toxicity in vitro of beta-amyloid protein. LL Iversen, RJ Mortishire-Smith, SJ Pollack, MS Shearman Biochemical Journal 311 (Pt 1), 1, 1995 | 617 | 1995 |
| NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats AW Nicholls, RJ Mortishire-Smith, JK Nicholson Chemical research in toxicology 16 (11), 1395-1404, 2003 | 281 | 2003 |
| ‘All‐in‐one’analysis for metabolite identification using liquid chromatography/hybrid quadrupole time‐of‐flight mass spectrometry with collision energy switching M Wrona, T Mauriala, KP Bateman, RJ Mortishire‐Smith, D O'Connor Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 210 | 2005 |
| Structure determination of tolaasin, an extracellular lipodepsipeptide produced by the mushroom pathogen, Pseudomonas tolaasii Paine JC Nutkins, RJ Mortishire-Smith, LC Packman, CL Brodey, PB Rainey, ... Journal of the American Chemical Society 113 (7), 2621-2627, 1991 | 209 | 1991 |
| High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease MR Pears, JD Cooper, HM Mitchison, RJ Mortishire-Smith, DA Pearce, ... Journal of Biological Chemistry 280 (52), 42508-42514, 2005 | 187 | 2005 |
| The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage λ repressor DNA-binding domain N Assa-Munt, RJ Mortishire-Smith, R Aurora, W Herr, PE Wright Cell 73 (1), 193-205, 1993 | 183 | 1993 |
| Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity RJ Mortishire-Smith, GL Skiles, JW Lawrence, S Spence, AW Nicholls, ... Chemical research in toxicology 17 (2), 165-173, 2004 | 180 | 2004 |
| Accelerated throughput metabolic route screening in early drug discovery using high‐resolution liquid chromatography/quadrupole time‐of‐flight mass spectrometry and automated … RJ Mortishire‐Smith, D O'Connor, JM Castro‐Perez, J Kirby Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 149 | 2005 |
| Automated assignment of high‐resolution collisionally activated dissociation mass spectra using a systematic bond disconnection approach AW Hill, RJ Mortishire‐Smith Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 141 | 2005 |
| Metabolite identification in drug discovery. AP Watt, RJ Mortishire-Smith, U Gerhard, SR Thomas Current opinion in drug discovery & development 6 (1), 57-65, 2003 | 96 | 2003 |
| Determination of the structure of an extracellular peptide produced by the mushroom saprotroph Pseudomonas reactans RJ Mortishire-Smith, JC Nutkins, LC Packman, CL Brodey, PB Rainey, ... Tetrahedron 47 (22), 3645-3654, 1991 | 96 | 1991 |
| Solution structure of the cytoplasmic domain of phospholamban: phosphorylation leads to a local perturbation in secondary structure RJ Mortishire-Smith, SM Pitzenberger, CJ Burke, CR Middaugh, ... Biochemistry 34 (23), 7603-7613, 1995 | 95 | 1995 |
| Stabilization of a Cis Amide Bond in a Host−Guest Complex GJ Pernía, JD Kilburn, JW Essex, RJ Mortishire-Smith, M Rowley Journal of the American Chemical Society 118 (42), 10220-10227, 1996 | 94 | 1996 |
| 4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors I Churcher, D Beher, JD Best, JL Castro, EE Clarke, A Gentry, T Harrison, ... Bioorganic & Medicinal Chemistry Letters 16 (2), 280-284, 2006 | 85 | 2006 |
| A functional analysis of mouse models of cardiac disease through metabolic profiling GLAH Jones, E Sang, C Goddard, RJ Mortishire-Smith, BC Sweatman, ... Journal of Biological Chemistry 280 (9), 7530-7539, 2005 | 82 | 2005 |
| Conserved positioning of proline residues in membrane-spanning helices of ion-channel proteins DN Woolfson, RJ Mortishire-Smith, DH Williams Biochemical and biophysical research communications 175 (3), 733-737, 1991 | 78 | 1991 |
| Generic dealkylation: a tool for increasing the hit‐rate of metabolite rationalization, and automatic customization of mass defect filters RJ Mortishire‐Smith, JM Castro‐Perez, K Yu, JP Shockcor, J Goshawk, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009 | 74 | 2009 |
| Development and validation of a higher-throughput equilibrium dialysis assay for plasma protein binding S van Liempd, D Morrison, L Sysmans, P Nelis, R Mortishire-Smith JALA: Journal of the Association for Laboratory Automation 16 (1), 56-67, 2011 | 73 | 2011 |
| Ultra‐performance liquid chromatography coupled to time‐of‐flight mass spectrometry for robust, high‐throughput quantitative analysis of an automated metabolic stability assay … D O'Connor, R Mortishire‐Smith, D Morrison, A Davies, M Dominguez Rapid communications in mass spectrometry 20 (5), 851-857, 2006 | 73 | 2006 |
| A proteomic investigation of drug-induced steatosis in rat liver G Meneses-Lorente, PC Guest, J Lawrence, N Muniappa, MR Knowles, ... Chemical research in toxicology 17 (5), 605-612, 2004 | 73 | 2004 |
