Russell Mortishire-Smith
Russell Mortishire-Smith
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The toxicity in vitro of beta-amyloid protein.
LL Iversen, RJ Mortishire-Smith, SJ Pollack, MS Shearman
Biochemical Journal 311 (Pt 1), 1, 1995
NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats
AW Nicholls, RJ Mortishire-Smith, JK Nicholson
Chemical research in toxicology 16 (11), 1395-1404, 2003
Structure determination of tolaasin, an extracellular lipodepsipeptide produced by the mushroom pathogen, Pseudomonas tolaasii Paine
JC Nutkins, RJ Mortishire-Smith, LC Packman, CL Brodey, PB Rainey, ...
Journal of the American Chemical Society 113 (7), 2621-2627, 1991
‘All‐in‐one’analysis for metabolite identification using liquid chromatography/hybrid quadrupole time‐of‐flight mass spectrometry with collision energy switching
M Wrona, T Mauriala, KP Bateman, RJ Mortishire‐Smith, D O'Connor
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease
MR Pears, JD Cooper, HM Mitchison, RJ Mortishire-Smith, DA Pearce, ...
Journal of Biological Chemistry 280 (52), 42508-42514, 2005
The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage λ repressor DNA-binding domain
N Assa-Munt, RJ Mortishire-Smith, R Aurora, W Herr, PE Wright
Cell 73 (1), 193-205, 1993
Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity
RJ Mortishire-Smith, GL Skiles, JW Lawrence, S Spence, AW Nicholls, ...
Chemical research in toxicology 17 (2), 165-173, 2004
Accelerated throughput metabolic route screening in early drug discovery using high‐resolution liquid chromatography/quadrupole time‐of‐flight mass spectrometry and automated …
RJ Mortishire‐Smith, D O'Connor, JM Castro‐Perez, J Kirby
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005
Automated assignment of high‐resolution collisionally activated dissociation mass spectra using a systematic bond disconnection approach
AW Hill, RJ Mortishire‐Smith
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005
Solution structure of the cytoplasmic domain of phospholamban: phosphorylation leads to a local perturbation in secondary structure
RJ Mortishire-Smith, SM Pitzenberger, CJ Burke, CR Middaugh, ...
Biochemistry 34 (23), 7603-7613, 1995
Determination of the structure of an extracellular peptide produced by the mushroom saprotroph Pseudomonas reactans
RJ Mortishire-Smith, JC Nutkins, LC Packman, CL Brodey, PB Rainey, ...
Tetrahedron 47 (22), 3645-3654, 1991
Metabolite identification in drug discovery.
AP Watt, RJ Mortishire-Smith, U Gerhard, SR Thomas
Current opinion in drug discovery & development 6 (1), 57-65, 2003
Stabilization of a Cis Amide Bond in a Host−Guest Complex
GJ Pernía, JD Kilburn, JW Essex, RJ Mortishire-Smith, M Rowley
Journal of the American Chemical Society 118 (42), 10220-10227, 1996
A functional analysis of mouse models of cardiac disease through metabolic profiling
GLAH Jones, E Sang, C Goddard, RJ Mortishire-Smith, BC Sweatman, ...
Journal of Biological Chemistry 280 (9), 7530-7539, 2005
4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors
I Churcher, D Beher, JD Best, JL Castro, EE Clarke, A Gentry, T Harrison, ...
Bioorganic & Medicinal Chemistry Letters 16 (2), 280-284, 2006
Conserved positioning of proline residues in membrane-spanning helices of ion-channel proteins
DN Woolfson, RJ Mortishire-Smith, DH Williams
Biochemical and biophysical research communications 175 (3), 733-737, 1991
A proteomic investigation of drug-induced steatosis in rat liver
G Meneses-Lorente, PC Guest, J Lawrence, N Muniappa, MR Knowles, ...
Chemical research in toxicology 17 (5), 605-612, 2004
Generic dealkylation: a tool for increasing the hit‐rate of metabolite rationalization, and automatic customization of mass defect filters
RJ Mortishire‐Smith, JM Castro‐Perez, K Yu, JP Shockcor, J Goshawk, ...
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009
Ultra‐performance liquid chromatography coupled to time‐of‐flight mass spectrometry for robust, high‐throughput quantitative analysis of an automated metabolic stability assay …
D O'Connor, R Mortishire‐Smith, D Morrison, A Davies, M Dominguez
Rapid communications in mass spectrometry 20 (5), 851-857, 2006
Product ion mobility as a promising tool for assignment of positional isomers of drug metabolites
F Cuyckens, C Wassvik, RJ Mortishire‐Smith, G Tresadern, I Campuzano, ...
Rapid Communications in Mass Spectrometry 25 (23), 3497-3503, 2011
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