Dominic G. Hoch
Dominic G. Hoch
Bestätigte E-Mail-Adresse bei ethz.ch
Titel
Zitiert von
Zitiert von
Jahr
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor
D Abegg, G Gasparini, DG Hoch, A Shuster, E Bartolami, S Matile, ...
Journal of the American Chemical Society 139 (1), 231-238, 2017
622017
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ...
Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020
332020
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin
MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ...
Journal of the American Chemical Society 141 (7), 2960-2974, 2019
312019
Chemoproteomics‐Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT
C Wang, D Abegg, DG Hoch, A Adibekian
Angewandte Chemie International Edition 55 (8), 2911-2915, 2016
312016
Divergent synthesis and identification of the cellular targets of deoxyelephantopins
R Lagoutte, C Serba, D Abegg, DG Hoch, A Adibekian, N Winssinger
Nature communications 7 (1), 1-11, 2016
242016
Cysteine-reactive probes and their use in chemical proteomics
DG Hoch, D Abegg, A Adibekian
Chemical Communications 54 (36), 4501-4512, 2018
232018
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids
DC Davis, DG Hoch, L Wu, D Abegg, BS Martin, ZY Zhang, A Adibekian, ...
Journal of the American Chemical Society 140 (50), 17465-17473, 2018
142018
Combined omics approach identifies gambogic acid and related xanthones as covalent inhibitors of the serine palmitoyltransferase complex
DG Hoch, D Abegg, JT Hannich, D Pechalrieu, A Shuster, BG Dwyer, ...
Cell chemical biology 27 (5), 586-597. e12, 2020
42020
Chemoproteomik‐vermittelte Entdeckung eines potenten und selektiven Inhibitors des DNA‐Reparaturproteins MGMT
C Wang, D Abegg, DG Hoch, A Adibekian
Angewandte Chemie 128 (8), 2964-2968, 2016
32016
Cysteine-specific Chemical Proteomics: From Target Identification to Drug Discovery
DG Hoch, D Abegg, C Wang, A Shuster, A Adibekian
CHIMIA International Journal for Chemistry 70 (11), 764-767, 2016
22016
Total Synthesis and Chemoproteomics Connect Curcusone Diterpenes with Oncogenic Protein BRAT1
C Cui, BG Dwyer, C Liu, D Abegg, Z Cai, D Hoch, X Yin, N Qiu, J Liu, ...
ChemRxiv, 2020
12020
Total Synthesis and Target Identification of the Curcusone Diterpenes
C Cui, BG Dwyer, C Liu, D Abegg, ZJ Cai, DG Hoch, X Yin, N Qiu, JQ Liu, ...
Journal of the American Chemical Society 143 (11), 4379-4386, 2021
2021
Chemoproteomics‐Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
BG Dwyer, C Wang, D Abegg, B Racioppo, N Qiu, Z Zhao, D Pechalrieu, ...
Angewandte Chemie International Edition 60 (6), 3071-3079, 2021
2021
Novel sesquiterpenoid analogs
M Dai, DC Davis, A Adibekian, DG Hoch, ZY Zhang
US Patent App. 16/531,185, 2020
2020
RIBOTACs–Targeted Degradation of RNA
MG COSTALES, H AIKAWA, Y LI, JL CHILDS-DISNEY, D ABEGG, ...
Proc. Natl. Acad. Sci. USA 117, 2406-2411, 2020
2020
Discovery of targets of cysteine-reactive natural products
DG Hoch
University of Geneva, 2019
2019
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