Margot Ernst
Margot Ernst
Bestätigte E-Mail-Adresse bei meduniwien.ac.at
TitelZitiert vonJahr
Comparative modeling of GABAA receptors: limits, insights, future developments
M Ernst, D Brauchart, S Boresch, W Sieghart
Neuroscience 119 (4), 933-943, 2003
1792003
Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function
M Ernst, S Bruckner, S Boresch, W Sieghart
Molecular pharmacology 68 (5), 1291-1300, 2005
1412005
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands
L Richter, C De Graaf, W Sieghart, Z Varagic, M Mörzinger, IJP De Esch, ...
Nature chemical biology 8 (5), 455, 2012
1402012
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines
R Spurny, J Ramerstorfer, K Price, M Brams, M Ernst, H Nury, M Verheij, ...
Proceedings of the National Academy of Sciences 109 (44), E3028-E3034, 2012
1132012
The GABAA receptor α+ β− interface: a novel target for subtype selective drugs
J Ramerstorfer, R Furtmüller, I Sarto-Jackson, Z Varagic, W Sieghart, ...
Journal of neuroscience 31 (3), 870-877, 2011
902011
An updated unified pharmacophore model of the benzodiazepine binding site on γ-aminobutyric acida receptors: correlation with comparative models
T Clayton, JL Chen, M Ernst, L Richter, BA Cromer, CJ Morton, H Ng, ...
Current medicinal chemistry 14 (26), 2755-2775, 2007
752007
Heterogeneity of GABAA receptors: revived interest in the development of subtype-selective drugs
W Sieghart, M Ernst
Current Medicinal Chemistry-Central Nervous System Agents 5 (3), 217-242, 2005
712005
A novel GABAA receptor pharmacology: drugs interacting with the α+ β‐interface
W Sieghart, J Ramerstorfer, I Sarto‐Jackson, Z Varagic, M Ernst
British journal of pharmacology 166 (2), 476-485, 2012
642012
Computational thermochemistry of medium-sized silicon hydrides
G Katzer, MC Ernst, AF Sax, J Kalcher
The Journal of Physical Chemistry A 101 (21), 3942-3958, 1997
611997
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor γ2 subunit
W Ogris, A Pöltl, B Hauer, M Ernst, A Oberto, P Wulff, H Höger, W Wisden, ...
Biochemical pharmacology 68 (8), 1621-1629, 2004
562004
Structural studies of GABAA receptor binding sites: which experimental structure tells us what?
R Puthenkalam, M Hieckel, X Simeone, C Suwattanasophon, ...
Frontiers in molecular neuroscience 9, 44, 2016
432016
Subtype selectivity of α+ β− site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors
Z Varagic, J Ramerstorfer, S Huang, S Rallapalli, I Sarto‐Jackson, J Cook, ...
British journal of pharmacology 169 (2), 384-399, 2013
402013
Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+ β− interface
Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ...
British journal of pharmacology 169 (2), 371-383, 2013
282013
Accepted Article
Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ...
28*2013
Molecular analysis of the site for 2‐arachidonylglycerol (2‐AG) on the β2 subunit of GABAA receptors
R Baur, M Kielar, L Richter, M Ernst, GF Ecker, E Sigel
Journal of neurochemistry 126 (1), 29-36, 2013
242013
Proximity-accelerated Chemical Coupling Reaction in the Benzodiazepine-binding Site of γ-Aminobutyric Acid Type A Receptors SUPERPOSITION OF DIFFERENT ALLOSTERIC MODULATORS
KR Tan, A Gonthier, R Baur, M Ernst, M Goeldner, E Sigel
Journal of biological chemistry 282 (36), 26316-26325, 2007
232007
Identification of amino acid residues important for assembly of GABAA receptor α1 and γ2 subunits
I Sarto‐Jackson, J Ramerstorfer, M Ernst, W Sieghart
Journal of neurochemistry 96 (4), 983-995, 2006
192006
Identification Of Amino Acid Residues Important For Assembly Of Gabaa Receptor Alpha1 And Gamma2 Subunits
I Sarto-Jackson, J Ramerstorfer, M Ernst, W Sieghart
Journal of Neurochemistry 94, 59, 2005
192005
Raman and infrared vibrational spectra, normal coordinate analysis and ab initio calculations of 1, 1, 2, 2‐tetrachlorodisilane and ab initio calculations of hexachlorodisilane
M Ernst, K Schenzel, A Jähn, W Köll, K Hassler
Journal of Raman spectroscopy 28 (8), 589-597, 1997
191997
Intramolecular H-transfer reactions in Si2Hn (for n= 3–5)
MC Ernst, AF Sax, J Kalcher
Chemical physics letters 216 (1-2), 189-193, 1993
181993
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