Margot Ernst
Margot Ernst
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Cited by
Cited by
Comparative modeling of GABAA receptors: limits, insights, future developments
M Ernst, D Brauchart, S Boresch, W Sieghart
Neuroscience 119 (4), 933-943, 2003
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands
L Richter, C De Graaf, W Sieghart, Z Varagic, M Mörzinger, IJP De Esch, ...
Nature chemical biology 8 (5), 455, 2012
Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function
M Ernst, S Bruckner, S Boresch, W Sieghart
Molecular pharmacology 68 (5), 1291-1300, 2005
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines
R Spurny, J Ramerstorfer, K Price, M Brams, M Ernst, H Nury, M Verheij, ...
Proceedings of the National Academy of Sciences 109 (44), E3028-E3034, 2012
The GABAA receptor α+ β− interface: a novel target for subtype selective drugs
J Ramerstorfer, R Furtmüller, I Sarto-Jackson, Z Varagic, W Sieghart, ...
Journal of neuroscience 31 (3), 870-877, 2011
An updated unified pharmacophore model of the benzodiazepine binding site on γ-aminobutyric acida receptors: correlation with comparative models
T Clayton, JL Chen, M Ernst, L Richter, BA Cromer, CJ Morton, H Ng, ...
Current medicinal chemistry 14 (26), 2755-2775, 2007
Heterogeneity of GABAA receptors: revived interest in the development of subtype-selective drugs
W Sieghart, M Ernst
Current Medicinal Chemistry-Central Nervous System Agents 5 (3), 217-242, 2005
A novel GABAA receptor pharmacology: drugs interacting with the α+ β‐interface
W Sieghart, J Ramerstorfer, I Sarto‐Jackson, Z Varagic, M Ernst
British journal of pharmacology 166 (2), 476-485, 2012
Computational thermochemistry of medium-sized silicon hydrides
G Katzer, MC Ernst, AF Sax, J Kalcher
The Journal of Physical Chemistry A 101 (21), 3942-3958, 1997
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor γ2 subunit
W Ogris, A Pöltl, B Hauer, M Ernst, A Oberto, P Wulff, H Höger, W Wisden, ...
Biochemical pharmacology 68 (8), 1621-1629, 2004
Structural studies of GABAA receptor binding sites: which experimental structure tells us what?
R Puthenkalam, M Hieckel, X Simeone, C Suwattanasophon, ...
Frontiers in molecular neuroscience 9, 44, 2016
Subtype selectivity of α+ β− site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors
Z Varagic, J Ramerstorfer, S Huang, S Rallapalli, I Sarto‐Jackson, J Cook, ...
British journal of pharmacology 169 (2), 384-399, 2013
Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+ β− interface
Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ...
British journal of pharmacology 169 (2), 371-383, 2013
Accepted Article
Z Varagic, L Wimmer, M Schnürch, MD Mihovilovic, S Huang, S Rallapalli, ...
Molecular analysis of the site for 2‐arachidonylglycerol (2‐AG) on the β2 subunit of GABAA receptors
R Baur, M Kielar, L Richter, M Ernst, GF Ecker, E Sigel
Journal of neurochemistry 126 (1), 29-36, 2013
Proximity-accelerated Chemical Coupling Reaction in the Benzodiazepine-binding Site of γ-Aminobutyric Acid Type A Receptors SUPERPOSITION OF DIFFERENT ALLOSTERIC MODULATORS
KR Tan, A Gonthier, R Baur, M Ernst, M Goeldner, E Sigel
Journal of biological chemistry 282 (36), 26316-26325, 2007
Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments
GS Forkuo, ML Guthrie, NY Yuan, AN Nieman, R Kodali, R Jahan, ...
Molecular pharmaceutics 13 (6), 2026-2038, 2016
Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site‐directed mutagenesis
D Luger, G Poli, M Wieder, M Stadler, S Ke, M Ernst, A Hohaus, T Linder, ...
British journal of pharmacology 172 (22), 5403-5413, 2015
Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved …
DE Knutson, R Kodali, B Divović, M Treven, MR Stephen, NM Zahn, ...
Journal of medicinal chemistry, 2018
Raman and infrared vibrational spectra, normal coordinate analysis and ab initio calculations of 1, 1, 2, 2‐tetrachlorodisilane and ab initio calculations of hexachlorodisilane
M Ernst, K Schenzel, A Jähn, W Köll, K Hassler
Journal of Raman spectroscopy 28 (8), 589-597, 1997
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