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Monica L. Fernández-Quintero
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Broadly neutralizing antibodies target a haemagglutinin anchor epitope
JJ Guthmiller, J Han, HA Utset, L Li, LYL Lan, C Henry, CT Stamper, ...
Nature 602 (7896), 314-320, 2022
722022
Characterizing the diversity of the CDR-H3 loop conformational ensembles in relationship to antibody binding properties
ML Fernández-Quintero, JR Loeffler, J Kraml, U Kahler, AS Kamenik, ...
Frontiers in immunology 9, 3065, 2019
712019
Polyreactive broadly neutralizing B cells are selected to provide defense against pandemic threat influenza viruses
JJ Guthmiller, LYL Lan, ML Fernández-Quintero, J Han, HA Utset, DJ Bitar, ...
Immunity 53 (6), 1230-1244. e5, 2020
662020
CDR-H3 loop ensemble in solution–conformational selection upon antibody binding
ML Fernández-Quintero, J Kraml, G Georges, KR Liedl
MAbs 11 (6), 1077-1088, 2019
482019
Antibodies exhibit multiple paratope states influencing VH–VL domain orientations
ML Fernández-Quintero, ND Pomarici, BA Math, KB Kroell, F Waibl, ...
Communications biology 3 (1), 589, 2020
422020
Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder
NT Hofer, P Tuluc, NJ Ortner, YV Nikonishyna, ML Fernándes-Quintero, ...
Molecular autism 11, 1-18, 2020
402020
Local and global rigidification upon antibody affinity maturation
ML Fernández-Quintero, JR Loeffler, LM Bacher, F Waibl, CA Seidler, ...
Frontiers in molecular biosciences 7, 182, 2020
322020
VH‐VL interdomain dynamics observed by computer simulations and NMR
ML Fernández‐Quintero, VJ Hoerschinger, LM Lamp, A Bujotzek, ...
Proteins: Structure, Function, and Bioinformatics 88 (7), 830-839, 2020
302020
Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures
ML Fernández-Quintero, MC Heiss, ND Pomarici, BA Math, KR Liedl
MAbs 12 (1), 1744328, 2020
302020
CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders
Y El Ghaleb, PE Schneeberger, ML Fernández-Quintero, SM Geisler, ...
Brain 144 (7), 2092-2106, 2021
292021
Structural determinants of voltage-gating properties in calcium channels
ML Fernández-Quintero, Y El Ghaleb, P Tuluc, M Campiglio, KR Liedl, ...
Elife 10, e64087, 2021
252021
Mutation of framework residue H71 results in different antibody paratope states in solution
ML Fernández-Quintero, KB Kroell, F Hofer, JR Riccabona, KR Liedl
Frontiers in Immunology 12, 243, 2021
252021
Conformational ensembles of antibodies determine their hydrophobicity
F Waibl, ML Fernández-Quintero, AS Kamenik, J Kraml, F Hofer, ...
Biophysical Journal 120 (1), 143-157, 2021
242021
T-cell receptor CDR3 loop conformations in solution shift the relative VH-VL domain distributions
ML Fernández-Quintero, ND Pomarici, JR Loeffler, CA Seidler, KR Liedl
Frontiers in Immunology 11, 1440, 2020
222020
Ensembles in solution as a new paradigm for antibody structure prediction and design
ML Fernández-Quintero, G Georges, JM Varga, KR Liedl
MAbs 13 (1), 1923122, 2021
202021
Transitions of CDR-L3 loop canonical cluster conformations on the micro-to-millisecond timescale
ML Fernández-Quintero, BA Math, JR Loeffler, KR Liedl
Frontiers in immunology 10, 2652, 2019
182019
Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes
ML Fernández-Quintero, JR Loeffler, F Waibl, AS Kamenik, F Hofer, ...
Protein Engineering, Design and Selection 32 (11), 513-523, 2019
182019
Antibody humanization—the Influence of the antibody framework on the CDR-H3 loop ensemble in solution
ML Fernández-Quintero, MC Heiss, KR Liedl
Protein Engineering, Design and Selection 32 (9), 411-422, 2019
182019
Challenges in antibody structure prediction
ML Fernández-Quintero, J Kokot, F Waibl, ALM Fischer, PK Quoika, ...
MAbs 15 (1), 2175319, 2023
172023
Surprisingly fast interface and elbow angle dynamics of antigen-binding fragments
ML Fernández-Quintero, KB Kroell, MC Heiss, JR Loeffler, PK Quoika, ...
Frontiers in Molecular Biosciences 7, 2020
172020
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