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Honghui Zhou
Honghui Zhou
Head of Pharmacometrics (US), Janssen Research & Development, Johnson & Johnson
Bestätigte E-Mail-Adresse bei its.jnj.com
Titel
Zitiert von
Zitiert von
Jahr
Association between serum concentration of infliximab and efficacy in adult patients with ulcerative colitis
OJ Adedokun, WJ Sandborn, BG Feagan, P Rutgeerts, Z Xu, CW Marano, ...
Gastroenterology 147 (6), 1296-1307. e5, 2014
3542014
Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis
AA Fasanmade, OJ Adedokun, J Ford, D Hernandez, J Johanns, C Hu, ...
European journal of clinical pharmacology 65, 1211-1228, 2009
3452009
Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trials
AA Fasanmade, OJ Adedokun, M Blank, H Zhou, HM Davis
Clinical therapeutics 33 (7), 946-964, 2011
3152011
Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α
DJ Shealy, A Cai, K Staquet, A Baker, ER Lacy, L Johns, O Vafa, G Gunn, ...
MAbs 2 (4), 428-439, 2010
2942010
Pharmacokinetics and safety of golimumab, a fully human anti‐TNF‐α monoclonal antibody, in subjects with rheumatoid arthritis
H Zhou, H Jang, RM Fleischmann, E Bouman‐Thio, Z Xu, JC Marini, ...
The Journal of Clinical Pharmacology 47 (3), 383-396, 2007
2252007
Population pharmacokinetic modeling of ustekinumab, a human monoclonal antibody targeting IL‐12/23p40, in patients with moderate to severe plaque psoriasis
Y Zhu, C Hu, M Lu, S Liao, JC Marini, J Yohrling, N Yeilding, HM Davis, ...
The Journal of Clinical Pharmacology 49 (2), 162-175, 2009
1722009
Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab
JM Benson, CW Sachs, G Treacy, H Zhou, CE Pendley, CM Brodmerkel, ...
Nature biotechnology 29 (7), 615-624, 2011
1672011
Clinical pharmacokinetics of etanercept: a fully humanized soluble recombinant tumor necrosis factor receptor fusion protein
H Zhou
The Journal of Clinical Pharmacology 45 (5), 490-497, 2005
1572005
Pharmacokinetic strategies in deciphering atypical drug absorption profiles
H Zhou
The Journal of Clinical Pharmacology 43 (3), 211-227, 2003
1522003
Characterizing the impact of renal impairment on the clinical pharmacology of biologics
B Meibohm, H Zhou
The Journal of Clinical Pharmacology 52 (S1), 54S-62S, 2012
1392012
Population pharmacokinetics of infliximab in patients with ankylosing spondylitis
Z Xu, K Seitz, A Fasanmade, J Ford, P Williamson, W Xu, HM Davis, ...
The Journal of Clinical Pharmacology 48 (6), 681-695, 2008
1372008
Interspecies scaling of therapeutic monoclonal antibodies: initial look
J Ling, H Zhou, Q Jiao, HM Davis
The Journal of Clinical Pharmacology 49 (12), 1382-1402, 2009
1342009
Molecular, biologic, and pharmacokinetic properties of monoclonal antibodies: impact of these parameters on early clinical development
MA Mascelli, H Zhou, R Sweet, J Getsy, HM Davis, M Graham, ...
The Journal of Clinical Pharmacology 47 (5), 553-565, 2007
1222007
Pharmacokinetics and exposure-response relationship of golimumab in patients with moderately-to-severely active ulcerative colitis: results from phase 2/3 PURSUIT induction and …
OJ Adedokun, Z Xu, CW Marano, R Strauss, H Zhang, J Johanns, H Zhou, ...
Journal of Crohn's and Colitis 11 (1), 35-46, 2017
1212017
Pharmacokinetics, pharmacodynamics and safety of a human anti‐IL‐6 monoclonal antibody (sirukumab) in healthy subjects in a first‐in‐human study
Z Xu, E Bouman‐Thio, C Comisar, B Frederick, B Van Hartingsveldt, ...
British journal of clinical pharmacology 72 (2), 270-281, 2011
1152011
Population pharmacokinetics of golimumab, an anti‐tumor necrosis factor‐α human monoclonal antibody, in patients with psoriatic arthritis
Z Xu, T Vu, H Lee, C Hu, J Ling, H Yan, D Baker, A Beutler, C Pendley, ...
The Journal of Clinical Pharmacology 49 (9), 1056-1070, 2009
1122009
“Cocktail” approaches and strategies in drug development: valuable tool or flawed science?
H Zhou, Z Tong, JF McLeod
The Journal of Clinical Pharmacology 44 (2), 120-134, 2004
1082004
Development of the IL‐12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives–an update
N Yeilding, P Szapary, C Brodmerkel, J Benson, M Plotnick, H Zhou, ...
Annals of the New York Academy of Sciences 1263 (1), 1-12, 2012
1042012
Subcutaneous bioavailability of golimumab at 3 different injection sites in healthy subjects
Z Xu, Q Wang, Y Zhuang, B Frederick, H Yan, E Bouman‐Thio, JC Marini, ...
The Journal of Clinical Pharmacology 50 (3), 276-284, 2010
1012010
Population pharmacokinetic analysis and simulation of the time‐concentration profile of etanercept in pediatric patients with juvenile rheumatoid arthritis
DS Yim, H Zhou, M Buckwalter, I Nestorov, CC Peck, H Lee
The Journal of Clinical Pharmacology 45 (3), 246-256, 2005
972005
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