| Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome S Guidi, P Bonasoni, C Ceccarelli, D Santini, F Gualtieri, E Ciani, ... Brain Pathology 18 (2), 180-197, 2008 | 320 | 2008 |
| Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice A Contestabile, T Fila, C Ceccarelli, P Bonasoni, L Bonapace, D Santini, ... Hippocampus 17 (8), 665-678, 2007 | 313 | 2007 |
| Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome P Bianchi, E Ciani, S Guidi, S Trazzi, D Felice, G Grossi, M Fernandez, ... Journal of Neuroscience 30 (26), 8769-8779, 2010 | 240 | 2010 |
| Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation A Contestabile, E Ciani Neurochemistry international 45 (6), 903-914, 2004 | 217 | 2004 |
| hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer A Varrault, E Ciani, F Apiou, B Bilanges, A Hoffmann, C Pantaloni, ... Proceedings of the National Academy of Sciences 95 (15), 8835-8840, 1998 | 200 | 1998 |
| Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome S Guidi, E Ciani, P Bonasoni, D Santini, R Bartesaghi Brain pathology 21 (4), 361-373, 2011 | 182 | 2011 |
| Nitric oxide regulates cGMP‐dependent cAMP‐responsive element binding protein phosphorylation and Bcl‐2 expression in cerebellar neurons: implication for a survival role of … E Ciani, S Guidi, R Bartesaghi, A Contestabile Journal of neurochemistry 82 (5), 1282-1289, 2002 | 178 | 2002 |
| Mapping pathological phenotypes in a mouse model of CDKL5 disorder E Amendola, Y Zhan, C Mattucci, E Castroflorio, E Calcagno, C Fuchs, ... PloS one 9 (5), e91613, 2014 | 170 | 2014 |
| Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons E Ciani, L Grøneng, M Voltattorni, V Rolseth, A Contestabile, RE Paulsen Brain research 728 (1), 1-6, 1996 | 146 | 1996 |
| Timing of therapies for Down syndrome: the sooner, the better F Stagni, A Giacomini, S Guidi, E Ciani, R Bartesaghi Frontiers in behavioral neuroscience 9, 265, 2015 | 142 | 2015 |
| APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome S Trazzi, VM Mitrugno, E Valli, C Fuchs, S Rizzi, S Guidi, G Perini, ... Human molecular genetics 20 (8), 1560-1573, 2011 | 141 | 2011 |
| Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling C Fuchs, S Trazzi, R Torricella, R Viggiano, M De Franceschi, ... Neurobiology of disease 70, 53-68, 2014 | 137 | 2014 |
| Akt pathway mediates a cGMP‐dependent survival role of nitric oxide in cerebellar granule neurones E Ciani, M Virgili, A Contestabile Journal of neurochemistry 81 (2), 218-228, 2002 | 124 | 2002 |
| Brain nitric oxide and its dual role in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches A Contestabile, B Monti, A Contestabile, E Ciani Current medicinal chemistry 10 (20), 2147-2174, 2003 | 122 | 2003 |
| Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome P Bianchi, E Ciani, A Contestabile, S Guidi, R Bartesaghi Brain Pathology 20 (1), 106-118, 2010 | 108 | 2010 |
| Is it possible to improve neurodevelopmental abnormalities in Down syndrome? R Bartesaghi, S Guidi, E Ciani Walter de Gruyter 22 (4), 419-455, 2011 | 104 | 2011 |
| Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia L Puccetti, F Santilli, AL Pasqui, S Lattanzio, R Liani, F Ciani, E Ferrante, ... Atherosclerosis 214 (1), 122-128, 2011 | 104 | 2011 |
| Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation E Ciani, S Guidi, G Della Valle, G Perini, R Bartesaghi, A Contestabile Journal of Biological Chemistry 277 (51), 49896-49902, 2002 | 101 | 2002 |
| Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model S Guidi, F Stagni, P Bianchi, E Ciani, A Giacomini, M De Franceschi, ... Brain 137 (2), 380-401, 2014 | 99 | 2014 |
| Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801 F Facchinetti, E Ciani, R Dall'Olio, M Virgili, A Contestabile, F Fonnum Developmental brain research 74 (2), 219-224, 1993 | 97 | 1993 |
