Five computational developability guidelines for therapeutic antibody profiling MIJ Raybould, C Marks, K Krawczyk, B Taddese, J Nowak, AP Lewis, ... Proceedings of the National Academy of Sciences 116 (10), 4025-4030, 2019 | 309 | 2019 |
ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins B Abanades, WK Wong, F Boyles, G Georges, A Bujotzek, CM Deane Communications Biology 6 (1), 575, 2023 | 153 | 2023 |
Thera-SAbDab: the therapeutic structural antibody database MIJ Raybould, C Marks, AP Lewis, J Shi, A Bujotzek, B Taddese, ... Nucleic acids research 48 (D1), D383-D388, 2020 | 144 | 2020 |
ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation B Abanades, G Georges, A Bujotzek, CM Deane Bioinformatics 38 (7), 1877-1880, 2022 | 131 | 2022 |
DNA-programmed spatial screening of carbohydrate–lectin interactions C Scheibe, A Bujotzek, J Dernedde, M Weber, O Seitz Chemical science 2 (4), 770-775, 2011 | 102 | 2011 |
Brain shuttle antibody for Alzheimer’s disease with attenuated peripheral effector function due to an inverted binding mode F Weber, B Bohrmann, J Niewoehner, JAA Fischer, P Rueger, ... Cell reports 22 (1), 149-162, 2018 | 94 | 2018 |
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities SX Cho, I Rudloff, JC Lao, MA Pang, R Goldberg, CB Bui, CA McLean, ... Nature communications 11 (1), 5794, 2020 | 85 | 2020 |
DNA‐controlled bivalent presentation of ligands for the estrogen receptor F Abendroth, A Bujotzek, M Shan, R Haag, M Weber, O Seitz Angewandte Chemie International Edition 37 (50), 8592-8596, 2011 | 73 | 2011 |
Quantifying the rebinding effect in multivalent chemical ligand-receptor systems M Weber, A Bujotzek, R Haag The Journal of chemical physics 137 (5), 2012 | 72 | 2012 |
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody C Augsberger, G Hänel, W Xu, V Pulko, LJ Hanisch, A Augustin, J Challier, ... Blood, The Journal of the American Society of Hematology 138 (25), 2655-2669, 2021 | 61 | 2021 |
Prediction of VH–VL domain orientation for antibody variable domain modeling A Bujotzek, J Dunbar, F Lipsmeier, W Schäfer, I Antes, CM Deane, ... Proteins: Structure, Function, and Bioinformatics 83 (4), 681-695, 2015 | 60 | 2015 |
Antibodies exhibit multiple paratope states influencing VH–VL domain orientations ML Fernández-Quintero, ND Pomarici, BA Math, KB Kroell, F Waibl, ... Communications biology 3 (1), 589, 2020 | 51 | 2020 |
Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope WK Wong, SA Robinson, A Bujotzek, G Georges, AP Lewis, J Shi, ... MAbs 13 (1), 1873478, 2021 | 40 | 2021 |
VH-VL orientation prediction for antibody humanization candidate selection: A case study A Bujotzek, F Lipsmeier, SF Harris, J Benz, A Kuglstatter, G Georges MAbs 8 (2), 288-305, 2016 | 37 | 2016 |
Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding M Shan, A Bujotzek, F Abendroth, A Wellner, R Gust, O Seitz, M Weber, ... ChemBioChem 12 (17), 2587-2598, 2011 | 31 | 2011 |
VH‐VL interdomain dynamics observed by computer simulations and NMR ML Fernández‐Quintero, VJ Hoerschinger, LM Lamp, A Bujotzek, ... Proteins: Structure, Function, and Bioinformatics 88 (7), 830-839, 2020 | 30 | 2020 |
Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor M Shan, KE Carlson, A Bujotzek, A Wellner, R Gust, M Weber, ... ACS chemical biology 8 (4), 707-715, 2013 | 27 | 2013 |
Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly JT Regula, S Imhof-Jung, M Mølhøj, J Benz, A Ehler, A Bujotzek, ... Protein Engineering, Design and Selection 31 (7-8), 289-299, 2018 | 24 | 2018 |
MoFvAb: Modeling the Fv region of antibodies A Bujotzek, A Fuchs, C Qu, J Benz, S Klostermann, I Antes, G Georges MAbs 7 (5), 838-852, 2015 | 24 | 2015 |
Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies S Dengl, E Hoffmann, M Grote, C Wagner, O Mundigl, G Georges, ... The FASEB Journal 29 (5), 1763, 2015 | 24 | 2015 |