|Restoration of p53 function leads to tumour regression in vivo|
A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ...
Nature 445 (7128), 661-665, 2007
|Conversion of Bcl-2 to a Bax-like death effector by caspases|
EHY Cheng, DG Kirsch, RJ Clem, R Ravi, MB Kastan, A Bedi, K Ueno, ...
Science 278 (5345), 1966-1968, 1997
|Modulation of cell death by Bcl-xL through caspase interaction|
RJ Clem, EHY Cheng, CL Karp, DG Kirsch, K Ueno, A Takahashi, ...
Proceedings of the National Academy of Sciences 95 (2), 554-559, 1998
|Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c|
DG Kirsch, A Doseff, BN Chau, DS Lim, NC de Souza-Pinto, R Hansford, ...
Journal of Biological Chemistry 274 (30), 21155-21161, 1999
|Dicer1 functions as a haploinsufficient tumor suppressor|
MS Kumar, RE Pester, CY Chen, K Lane, C Chin, J Lu, DG Kirsch, ...
Genes & development 23 (23), 2700-2704, 2009
|Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2–positive breast cancer|
NU Lin, LA Carey, MC Liu, J Younger, SE Come, M Ewend, GJ Harris, ...
Journal of clinical oncology: official journal of the American Society of …, 2008
|Animal models for medical countermeasures to radiation exposure|
JP Williams, SL Brown, GE Georges, M Hauer-Jensen, RP Hill, AK Huser, ...
Radiation research 173 (4), 557-578, 2010
|Strategies for optimizing the response of cancer and normal tissues to radiation|
EJ Moding, MB Kastan, DG Kirsch
Nature reviews Drug discovery 12 (7), 526-542, 2013
|Tumor-suppressor p53: implications for tumor development and prognosis.|
DG Kirsch, MB Kastan
Journal of clinical oncology 16 (9), 3158-3168, 1998
|Dietary methionine influences therapy in mouse cancer models and alters human metabolism|
X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ...
Nature 572 (7769), 397-401, 2019
|A spatially and temporally restricted mouse model of soft tissue sarcoma|
DG Kirsch, DM Dinulescu, JB Miller, J Grimm, PM Santiago, NP Young, ...
Nature medicine 13 (8), 992-997, 2007
|Treatment and outcome of 82 patients with angiosarcoma|
JA Abraham, FJ Hornicek, AM Kaufman, DC Harmon, DS Springfield, ...
Annals of surgical oncology 14, 1953-1967, 2007
|A plasmonic gold nanostar theranostic probe for in vivo tumor imaging and photothermal therapy|
Y Liu, JR Ashton, EJ Moding, H Yuan, JK Register, AM Fales, J Choi, ...
Theranostics 5 (9), 946, 2015
|p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis|
DG Kirsch, PM Santiago, E di Tomaso, JM Sullivan, WS Hou, T Dayton, ...
Science 327 (5965), 593, 2010
|Acetate production from glucose and coupling to mitochondrial metabolism in mammals|
X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao, MA Reid, J Liu, ...
Cell 175 (2), 502-513. e13, 2018
|Preoperative or postoperative radiotherapy versus surgery alone for retroperitoneal sarcoma: a case-control, propensity score-matched analysis of a nationwide clinical oncology …|
DP Nussbaum, CN Rushing, WO Lane, DM Cardona, DG Kirsch, ...
The Lancet Oncology 17 (7), 966-975, 2016
|Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis|
TSK Eisinger-Mathason, M Zhang, Q Qiu, N Skuli, MS Nakazawa, ...
Cancer discovery 3 (10), 1190-1205, 2013
|Significant reduction of late toxicities in patients with extremity sarcoma treated with image-guided radiation therapy to a reduced target volume: results of radiation therapy …|
D Wang, Q Zhang, BL Eisenberg, JM Kane, XA Li, D Lucas, IA Petersen, ...
Journal of Clinical Oncology 33 (20), 2231, 2015
|A next-generation dual-recombinase system for time-and host-specific targeting of pancreatic cancer|
N Schönhuber, B Seidler, K Schuck, C Veltkamp, C Schachtler, ...
Nature medicine 20 (11), 1340-1347, 2014
|A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer|
MJ Whitley, DM Cardona, AL Lazarides, I Spasojevic, JM Ferrer, J Cahill, ...
Science translational medicine 8 (320), 320ra4-320ra4, 2016