MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation SR Bacman, JHK Kauppila, CV Pereira, N Nissanka, M Miranda, M Pinto, ... Nature medicine 24 (11), 1696-1700, 2018 | 242 | 2018 |
Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety? CV Pereira, AC Moreira, SP Pereira, NG Machado, FS Carvalho, ... Current drug safety 4 (1), 34-54, 2009 | 118 | 2009 |
The contribution of oxidative stress to drug-induced organ toxicity and its detection in vitro and in vivo CV Pereira, S Nadanaciva, PJ Oliveira, Y Will Expert opinion on drug metabolism & toxicology 8 (2), 219-237, 2012 | 102 | 2012 |
Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia J Lumini-Oliveira, J Magalhães, CV Pereira, AC Moreira, PJ Oliveira, ... Mitochondrion 11 (1), 54-63, 2011 | 81 | 2011 |
mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels CV Pereira, SR Bacman, T Arguello, U Zekonyte, SL Williams, DR Edgell, ... EMBO molecular medicine 10 (9), e8084, 2018 | 72 | 2018 |
Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts AR Coelho, TR Martins, R Couto, C Deus, CV Pereira, RF Simões, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (11 …, 2017 | 71 | 2017 |
Mechanisms of berberine (natural yellow 18)–induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator CV Pereira, NG Machado, PJ Oliveira Toxicological sciences 105 (2), 408-417, 2008 | 66 | 2008 |
Regulation and protection of mitochondrial physiology by sirtuins CV Pereira, M Lebiedzinska, MR Wieckowski, PJ Oliveira Mitochondrion 12 (1), 66-76, 2012 | 63 | 2012 |
Photobiomodulation enhancement of cell proliferation at 660 nm does not require cytochrome c oxidase PLV Lima, CV Pereira, N Nissanka, T Arguello, G Gavini, ... Journal of Photochemistry and Photobiology B: Biology 194, 71-75, 2019 | 59 | 2019 |
Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo U Zekonyte, SR Bacman, J Smith, W Shoop, CV Pereira, G Tomberlin, ... Nature communications 12 (1), 3210, 2021 | 56 | 2021 |
SCO2 mutations cause early-onset axonal Charcot-Marie-Tooth disease associated with cellular copper deficiency AP Rebelo, D Saade, CV Pereira, A Farooq, TC Huff, L Abreu, CT Moraes, ... Brain 141 (3), 662-672, 2018 | 56 | 2018 |
Mitochondrial DNA double-strand breaks in oligodendrocytes cause demyelination, axonal injury, and CNS inflammation PM Madsen, M Pinto, S Patel, S McCarthy, H Gao, M Taherian, S Karmally, ... Journal of Neuroscience 37 (42), 10185-10199, 2017 | 46 | 2017 |
Mitochondrionopathy phenotype in doxorubicin-treated Wistar rats depends on treatment protocol and is cardiac-specific GC Pereira, SP Pereira, CV Pereira, JA Lumini, J Magalhães, A Ascensão, ... PLoS One 7 (6), e38867, 2012 | 45 | 2012 |
Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics JP Monteiro, CV Pereira, AM Silva, E Maciel, I Baldeiras, F Peixoto, ... Archives of Toxicology 87, 2151-2163, 2013 | 33 | 2013 |
Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms CV Pereira, PJ Oliveira, Y Will, S Nadanaciva Toxicology and applied pharmacology 264 (2), 167-181, 2012 | 31 | 2012 |
Cellular mechanisms of mtDNA heteroplasmy dynamics CV Pereira, BL Gitschlag, MR Patel Critical reviews in biochemistry and molecular biology 56 (5), 510-525, 2021 | 30 | 2021 |
Myopathy reversion in mice after restauration of mitochondrial complex I CV Pereira, S Peralta, T Arguello, SR Bacman, F Diaz, CT Moraes EMBO molecular medicine 12 (2), e10674, 2020 | 30 | 2020 |
Current strategies towards therapeutic manipulation of mtDNA heteroplasmy CV Pereira, CT Moraes Frontiers in bioscience (Landmark edition) 22, 991, 2017 | 29 | 2017 |
Biallelic loss-of-function variations in PRDX3 cause cerebellar ataxia AP Rebelo, I Eidhof, VP Cintra, L Guillot-Noel, CV Pereira, D Timmann, ... Brain 144 (5), 1467-1481, 2021 | 25 | 2021 |
Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats SP Pereira, GC Pereira, CV Pereira, FS Carvalho, MH Cordeiro, PC Mota, ... Environmental pollution 180, 281-290, 2013 | 23 | 2013 |