Gene essentiality and synthetic lethality in haploid human cells VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ... Science 350 (6264), 1092-1096, 2015 | 916 | 2015 |
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 M Rebsamen, L Pochini, T Stasyk, MEG de Araújo, M Galluccio, ... Nature 519 (7544), 477-481, 2015 | 707 | 2015 |
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis A Fauster, M Rebsamen, KVM Huber, JW Bigenzahn, A Stukalov, ... Cell death & disease 6 (5), e1767-e1767, 2015 | 196 | 2015 |
LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 191 | 2018 |
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study B Snijder, GI Vladimer, N Krall, K Miura, AS Schmolke, C Kornauth, ... The Lancet Haematology 4 (12), e595-e606, 2017 | 187 | 2017 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature, 1-7, 2020 | 171 | 2020 |
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia K Boztug, PM Järvinen, E Salzer, T Racek, S Mönch, W Garncarz, ... Nature genetics 46 (9), 1021-1027, 2014 | 144 | 2014 |
Recent advances in combinatorial drug screening and synergy scoring T Pemovska, JW Bigenzahn, G Superti-Furga Current opinion in pharmacology 42, 102-110, 2018 | 117 | 2018 |
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 80 | 2018 |
Global survey of the immunomodulatory potential of common drugs GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ... Nature chemical biology 13 (6), 681, 2017 | 74 | 2017 |
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response B Herdy, T Karonitsch, GI Vladimer, CSH Tan, A Stukalov, C Trefzer, ... European journal of immunology 45 (5), 1500-1511, 2015 | 60 | 2015 |
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking A Fauster, M Rebsamen, KL Willmann, A César-Razquin, E Girardi, ... Cell Death & Differentiation 26 (6), 1138-1155, 2019 | 36 | 2019 |
A time-resolved molecular map of the macrophage response to VSV infection RK Kandasamy, GI Vladimer, B Snijder, AC Müller, M Rebsamen, ... NPJ systems biology and applications 2 (1), 1-12, 2016 | 36 | 2016 |
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an … JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ... Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016 | 34 | 2016 |
Identifying kinase substrates via a heavy ATP kinase assay and quantitative mass spectrometry AC Müller, R Giambruno, J Weißer, P Májek, A Hofer, JW Bigenzahn, ... Scientific reports 6, 28107, 2016 | 30 | 2016 |
The effect of resveratrol in combination with irradiation and chemotherapy G Heiduschka, C Lill, R Seemann, M Brunner, R Schmid, R Houben, ... Strahlentherapie und Onkologie 190 (1), 75-80, 2014 | 24 | 2014 |
The comparability of anti-spike SARS-CoV-2 antibody tests is time-dependent: a prospective observational study T Perkmann, P Mucher, N Perkmann-Nagele, A Radakovics, M Repl, ... Microbiology Spectrum 10 (1), e01402-21, 2022 | 22 | 2022 |
Resveratrol synergistically enhances the effect of etoposide in HNSCC cell lines G Heiduschka, J Bigenzahn, M Brunner, D Thurnher Acta oto-laryngologica 134 (10), 1071-1078, 2014 | 16 | 2014 |
Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states KC Li, E Girardi, F Kartnig, S Grosche, T Pemovska, JW Bigenzahn, ... Nature metabolism 3 (5), 651-664, 2021 | 14 | 2021 |
Evaluation of Polo‐like kinase 1 as a potential therapeutic target in Merkel cell carcinoma L Kadletz, J Bigenzahn, D Thurnher, I Stanisz, BM Erovic, S Schneider, ... Head & neck 38 (S1), E1918-E1925, 2016 | 14 | 2016 |