David C. Linehan
David C. Linehan
Professor of Surgery, University of Rochester
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Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
UK Liyanage, TT Moore, HG Joo, Y Tanaka, V Herrmann, G Doherty, ...
The Journal of Immunology 169 (5), 2756-2761, 2002
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models
Y Zhu, BL Knolhoff, MA Meyer, TM Nywening, BL West, J Luo, ...
Cancer research 74 (18), 5057-5069, 2014
Pretreatment assessment of resectable and borderline resectable pancreatic cancer: expert consensus statement
MP Callery, KJ Chang, EK Fishman, MS Talamonti, L William Traverso, ...
Annals of surgical oncology 16, 1727-1733, 2009
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
JB Mitchem, DJ Brennan, BL Knolhoff, BA Belt, Y Zhu, DE Sanford, ...
Cancer research 73 (3), 1128-1141, 2013
Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET)
FG Fernandez, JA Drebin, DC Linehan, F Dehdashti, BA Siegel, ...
Annals of surgery 240 (3), 438-450, 2004
The accordion severity grading system of surgical complications
SM Strasberg, DC Linehan, WG Hawkins
Annals of surgery 250 (2), 177-186, 2009
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a …
TM Nywening, A Wang-Gillam, DE Sanford, BA Belt, RZ Panni, ...
The lancet oncology 17 (5), 651-662, 2016
Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide.
GE Peoples, PS Goedegebuure, R Smith, DC Linehan, I Yoshino, ...
Proceedings of the National Academy of Sciences 92 (2), 432-436, 1995
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis
DE Sanford, BA Belt, RZ Panni, A Mayer, AD Deshpande, D Carpenter, ...
Clinical cancer research 19 (13), 3404-3415, 2013
Surgical margin in hepatic resection for colorectal metastasis: a critical and improvable determinant of outcome
B Cady, RL Jenkins, GD Steele Jr, WD Lewis, MD Stone, WV McDermott, ...
Annals of surgery 227 (4), 566-571, 1998
Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability of hepatic colorectal metastases
FG Fernandez, J Ritter, JW Goodwin, DC Linehan, WG Hawkins, ...
Journal of the American College of Surgeons 200 (6), 845-853, 2005
Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer
MCB Tan, PS Goedegebuure, BA Belt, B Flaherty, N Sankpal, ...
The Journal of Immunology 182 (3), 1746-1755, 2009
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients
M Sausen, J Phallen, V Adleff, S Jones, RJ Leary, MT Barrett, ...
Nature communications 6 (1), 7686, 2015
Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
TM Nywening, BA Belt, DR Cullinan, RZ Panni, BJ Han, DE Sanford, ...
Gut 67 (6), 1112-1123, 2018
Radical antegrade modular pancreatosplenectomy
SM Strasberg, JA Drebin, D Linehan
Surgery 133 (5), 521-527, 2003
Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth
MR Porembka, JB Mitchem, BA Belt, CS Hsieh, HM Lee, J Herndon, ...
Cancer Immunology, Immunotherapy 61, 1373-1385, 2012
Intradermal radiocolloid and intraparenchymal blue dye injection optimize sentinel node identification in breast cancer patients
DC Linehan, ADK Hill, T Akhurst, H Yeung, SDJ Yeh, KN Tran, PI Borgen, ...
Annals of Surgical Oncology 6, 450-454, 1999
Magnetic resonance imaging facilitates breast conservation for occult breast cancer
JA Olson, EA Morris, KJV Zee, DC Linehan, PI Borgen
Annals of surgical oncology 7, 411-415, 2000
Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs)
YM Hashim, KM Trinkaus, DC Linehan, SS Strasberg, RC Fields, D Cao, ...
Annals of surgery 259 (2), 197-203, 2014
Prospective trial of a blood supply-based technique of pancreaticojejunostomy: effect on anastomotic failure in the Whipple procedure
SM Strasberg, JA Drebin, NA Mokadam, DW Green, KL Jones, JP Ehlers, ...
Journal of the American College of Surgeons 194 (6), 746-758, 2002
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