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Leah B. Bushin
Leah B. Bushin
Bestätigte E-Mail-Adresse bei ucsd.edu
Titel
Zitiert von
Zitiert von
Jahr
Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink
KR Schramma, LB Bushin, MR Seyedsayamdost
Nature chemistry 7 (5), 431-437, 2015
2152015
Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens
F Xu, B Nazari, K Moon, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 139 (27), 9203-9212, 2017
1522017
A genetics-free method for high-throughput discovery of cryptic microbial metabolites
F Xu, Y Wu, C Zhang, KM Davis, K Moon, LB Bushin, ...
Nature chemical biology 15 (2), 161-168, 2019
1262019
Charting an unexplored streptococcal biosynthetic landscape reveals a unique peptide cyclization motif
LB Bushin, KA Clark, I Pelczer, MR Seyedsayamdost
Journal of the American Chemical Society 140 (50), 17674-17684, 2018
862018
Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264
D Mao, LB Bushin, K Moon, Y Wu, MR Seyedsayamdost
Proceedings of the National Academy of Sciences 114 (14), E2920-E2928, 2017
812017
Radical approach to enzymatic β-thioether bond formation
A Caruso, LB Bushin, KA Clark, RJ Martinie, MR Seyedsayamdost
Journal of the American Chemical Society 141 (2), 990-997, 2018
772018
Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis
BK Okada, Y Wu, D Mao, LB Bushin, MR Seyedsayamdost
ACS chemical biology 11 (8), 2124-2130, 2016
742016
Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical S-Adenosylmethionine Enzymes
A Caruso, RJ Martinie, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 141 (42), 16610-16614, 2019
662019
Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae
M Metelev, A Arseniev, LB Bushin, K Kuznedelov, TO Artamonova, ...
ACS chemical biology 12 (3), 814-824, 2017
572017
Aliphatic ether bond formation expands the scope of radical SAM enzymes in natural product biosynthesis
KA Clark, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 141 (27), 10610-10615, 2019
542019
Discovery and biosynthesis of streptosactin, a sactipeptide with an alternative topology encoded by commensal bacteria in the human microbiome
LB Bushin, BC Covington, BE Rued, MJ Federle, MR Seyedsayamdost
Journal of the American Chemical Society 142 (38), 16265-16275, 2020
502020
Total synthesis and stereochemical assignment of streptide
NA Isley, Y Endo, ZC Wu, BC Covington, LB Bushin, MR Seyedsayamdost, ...
Journal of the American Chemical Society 141 (43), 17361-17369, 2019
502019
Quorum sensing in streptococcus mutans regulates production of tryglysin, a novel ras-ripp antimicrobial compound
BE Rued, BC Covington, LB Bushin, G Szewczyk, I Laczkovich, ...
MBio 12 (2), 10.1128/mbio. 02688-20, 2021
332021
RaS-riPPs in streptococci and the human microbiome
KA Clark, LB Bushin, MR Seyedsayamdost
ACS bio & med Chem Au 2 (4), 328-339, 2022
212022
Backbone-enabled peptide macrocyclization through late-stage palladium-catalyzed C–H activation
Z Bai, H Wang
Synlett 31 (03), 199-204, 2020
182020
Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs
LB Bushin, BC Covington, KA Clark, A Caruso, MR Seyedsayamdost
Nature Chemical Biology 18 (10), 1135-1143, 2022
142022
Guidelines for determining the structures of radical SAM enzyme-catalyzed modifications in the biosynthesis of RiPP natural products
LB Bushin, MR Seyedsayamdost
Methods in Enzymology 606, 439-460, 2018
122018
Mapping the trimethoprim-induced secondary metabolome of Burkholderia thailandensis. ACS Chem Biol 11: 2124–2130
BK Okada, Y Wu, D Mao, LB Bushin, MR Seyedsayamdost
92016
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis
BA Johnson, KA Clark, LB Bushin, CN Spolar, MR Seyedsayamdost
Journal of the American Chemical Society, 2024
12024
Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms
MR Seyedsayamdost, F Xu, WU Yihan, L Bushin, K Davis
US Patent 11,549,950, 2023
12023
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