| Discovery and resupply of pharmacologically active plant-derived natural products: A review AG Atanasov, B Waltenberger, EM Pferschy-Wenzig, T Linder, ... Biotechnology advances 33 (8), 1582-1614, 2015 | 3211 | 2015 |
| Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase H Pein, A Ville, S Pace, V Temml, U Garscha, M Raasch, K Alsabil, ... Nature communications 9 (1), 3834, 2018 | 130 | 2018 |
| Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin AM Schaible, H Traber, V Temml, SM Noha, R Filosa, A Peduto, ... Biochemical pharmacology 86 (4), 476-486, 2013 | 99 | 2013 |
| Anti-inflammatory activity of natural geranylated flavonoids: cyclooxygenase and lipoxygenase inhibitory properties and proteomic analysis Z Hanáková, J Hosek, Z Kutil, V Temml, P Landa, T Vanek, D Schuster, ... Journal of natural products 80 (4), 999-1006, 2017 | 97 | 2017 |
| Impact of wines and wine constituents on cyclooxygenase‐1, cyclooxygenase‐2, and 5‐lipoxygenase catalytic activity Z Kutil, V Temml, D Maghradze, M Pribylova, M Dvorakova, D Schuster, ... Mediators of inflammation 2014 (1), 178931, 2014 | 92 | 2014 |
| Pesticide contamination and associated risk factors at public playgrounds near intensively managed apple and wine orchards C Linhart, GH Niedrist, M Nagler, R Nagrani, V Temml, T Bardelli, ... Environmental Sciences Europe 31, 1-16, 2019 | 64 | 2019 |
| Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole KR Beck, M Bächler, A Vuorinen, S Wagner, M Akram, U Griesser, ... Biochemical pharmacology 130, 93-103, 2017 | 60 | 2017 |
| Pharmacophore modeling for COX-1 and-2 inhibitors with LigandScout in comparison to Discovery Studio V Temml, T Kaserer, Z Kutil, P Landa, T Vanek, D Schuster Future medicinal chemistry 6 (17), 1869-1881, 2014 | 57 | 2014 |
| Structure-based molecular modeling in SAR analysis and lead optimization V Temml, Z Kutil Computational and structural biotechnology journal 19, 1431-1444, 2021 | 46 | 2021 |
| Discovery of potent soluble epoxide hydrolase (sEH) inhibitors by pharmacophore-based virtual screening B Waltenberger, U Garscha, V Temml, J Liers, O Werz, D Schuster, ... Journal of Chemical Information and Modeling 56 (4), 747-762, 2016 | 46 | 2016 |
| Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase U Garscha, E Romp, S Pace, A Rossi, V Temml, D Schuster, S König, ... Scientific reports 7 (1), 9398, 2017 | 45 | 2017 |
| Discovery of new liver X receptor agonists by pharmacophore modeling and shape-based virtual screening V Temml, CV Voss, VM Dirsch, D Schuster Journal of chemical information and modeling 54 (2), 367-371, 2014 | 45 | 2014 |
| Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids V Leláková, K Šmejkal, K Jakubczyk, O Veselý, P Landa, J Václavík, ... Food chemistry 285, 431-440, 2019 | 44 | 2019 |
| Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening V Temml, U Garscha, E Romp, G Schubert, J Gerstmeier, Z Kutil, ... Scientific reports 7 (1), 42751, 2017 | 43 | 2017 |
| Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones P Landa, Z Kutil, V Temml, A Vuorinen, J Malik, M Dvorakova, P Marsik, ... Planta medica 78 (04), 326-333, 2012 | 40 | 2012 |
| Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2, 3-dioxygenase S Kuehnl, S Schroecksnadel, V Temml, JM Gostner, H Schennach, ... Phytomedicine 20 (13), 1190-1195, 2013 | 39 | 2013 |
| Ginkgolic acid is a multi-target inhibitor of key enzymes in pro-inflammatory lipid mediator biosynthesis J Gerstmeier, J Seegers, F Witt, B Waltenberger, V Temml, JM Rollinger, ... Frontiers in pharmacology 10, 797, 2019 | 37 | 2019 |
| Effect of Dietary Stilbenes on 5-Lipoxygenase and Cyclooxygenases Activities In Vitro Z Kutil, M Kvasnicova, V Temml, D Schuster, P Marsik, EF Cusimamani, ... International Journal of Food Properties 18 (7), 1471-1477, 2015 | 35 | 2015 |
| Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4‐benzoquinone that inhibits 5‐lipoxygenase AM Schaible, R Filosa, V Temml, V Krauth, M Matteis, A Peduto, F Bruno, ... British journal of pharmacology 171 (9), 2399-2412, 2014 | 34 | 2014 |
| The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo AM Schaible, R Filosa, V Krauth, V Temml, S Pace, U Garscha, S Liening, ... Biochemical pharmacology 112, 60-71, 2016 | 33 | 2016 |
