The Intronic Long Noncoding RNA ANRASSF1 Recruits PRC2 to the RASSF1A Promoter, Reducing the Expression of RASSF1A and Increasing Cell Proliferation FC Beckedorff, AC Ayupe, R Crocci-Souza, MS Amaral, HI Nakaya, ... PLoS genetics 9 (8), e1003705, 2013 | 216 | 2013 |
Dietary palmitic acid promotes a prometastatic memory via Schwann cells G Pascual, D Domínguez, M Elosúa-Bayes, F Beckedorff, C Laudanna, ... Nature 599 (7885), 485-490, 2021 | 151 | 2021 |
Long non-coding RNAs and their implications in cancer epigenetics FC Beckedorff, MS Amaral, C Deocesano-Pereira, S Verjovski-Almeida Bioscience reports 33 (4), e00061, 2013 | 127 | 2013 |
Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms HL Chan, F Beckedorff, Y Zhang, J Garcia-Huidobro, H Jiang, A Colaprico, ... Nature communications 9 (1), 1-16, 2018 | 119 | 2018 |
Schistosoma mansoni egg, adult male and female comparative gene expression analysis and identification of novel genes by RNA-Seq L Anderson, MS Amaral, F Beckedorff, LF Silva, B Dazzani, KC Oliveira, ... PLoS neglected tropical diseases 9 (12), e0004334, 2015 | 90 | 2015 |
Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome AC Ayupe, AC Tahira, L Camargo, FC Beckedorff, S Verjovski-Almeida, ... RNA biology 12 (8), 877-892, 2015 | 83 | 2015 |
The human integrator complex facilitates transcriptional elongation by endonucleolytic cleavage of nascent transcripts F Beckedorff, E Blumenthal, L Ferreira daSilva, Y Aoi, PR Cingaram, ... Cell reports 32 (3), 2020 | 78 | 2020 |
Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq GT Almeida, MS Amaral, FCF Beckedorff, JP Kitajima, R DeMarco, ... Experimental parasitology 132 (1), 22-31, 2012 | 53 | 2012 |
Splice variants of TLE family genes and up-regulation of a TLE3 isoform in prostate tumors HI Nakaya, FC Beckedorff, ML Baldini, AA Fachel, EM Reis, ... Biochemical and biophysical research communications 364 (4), 918-923, 2007 | 53 | 2007 |
TAF1 plays a critical role in AML1-ETO driven leukemogenesis Y Xu, N Man, D Karl, C Martinez, F Liu, J Sun, CJ Martinez, GM Martin, ... Nature communications 10 (1), 4925, 2019 | 47 | 2019 |
Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs J Yue, F Lai, F Beckedorff, A Zhang, C Pastori, R Shiekhattar Genes & development 31 (17), 1809-1820, 2017 | 42 | 2017 |
Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1 J Barra, GS Gaidosh, E Blumenthal, F Beckedorff, MM Tayari, N Kirstein, ... Science advances 6 (27), eaaz9072, 2020 | 38 | 2020 |
Targeted chemotherapy overcomes drug resistance in melanoma J Yue, R Vendramin, F Liu, O Lopez, MG Valencia, HG Dos Santos, ... Genes & development 34 (9-10), 637-649, 2020 | 29 | 2020 |
Integrator enforces the fidelity of transcriptional termination at protein-coding genes LF Dasilva, E Blumenthal, F Beckedorff, PR Cingaram, ... Science advances 7 (45), eabe3393, 2021 | 28 | 2021 |
The Integrator complex regulates microRNA abundance through RISC loading N Kirstein, S Dokaneheifard, PR Cingaram, MG Valencia, F Beckedorff, ... Science Advances 9 (6), eadf0597, 2023 | 16 | 2023 |
PVT1 signals an androgen-dependent transcriptional repression program in prostate cancer cells and a set of the repressed genes predicts high-risk tumors A Videira, FC Beckedorff, LF daSilva, S Verjovski-Almeida Cell Communication and Signaling 19, 1-16, 2021 | 14 | 2021 |
Chromatin landscape distinguishes the genomic loci of hundreds of androgen-receptor-associated LincRNAs from the loci of non-associated LincRNAs LF DaSilva, FC Beckedorff, AC Ayupe, MS Amaral, V Mesel, A Videira, ... Frontiers in genetics 9, 354705, 2018 | 14 | 2018 |
High-Quality Draft Genome Sequence Resources of Eight Xylella fastidiosa Strains Isolated from Citrus, Coffee, Plum, and Hibiscus in South America PM Pierry, WO de Santana, JP Kitajima, J Martins-Junior, PA Zaini, ... Phytopathology® 110 (11), 1751-1755, 2020 | 4 | 2020 |
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression G Mas, N Man, Y Nakata, C Martinez-Caja, D Karl, F Beckedorff, F Tamiro, ... The Journal of clinical investigation 133 (13), 2023 | 3 | 2023 |
Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide) JD Zeidler, CCS Chini, KS Kanamori, S Kashyap, JM Espindola-Netto, ... Iscience 25 (11), 2022 | 3 | 2022 |