| Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetzki, L Böhnke, ... Cell stem cell 28 (9), 1533-1548. e6, 2021 | 147 | 2021 |
| Sense-antisense lncRNA pair encoded by locus 6p22. 3 determines neuroblastoma susceptibility via the USP36-CHD7-SOX9 regulatory axis T Mondal, PK Juvvuna, A Kirkeby, S Mitra, ST Kosalai, L Traxler, ... Cancer cell 33 (3), 417-434. e7, 2018 | 133 | 2018 |
| Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ... Cell reports 23 (9), 2550-2558, 2018 | 114 | 2018 |
| Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease L Traxler, JR Herdy, D Stefanoni, S Eichhorner, S Pelucchi, A Szücs, ... Cell Metabolism 34 (9), 1248-1263. e6, 2022 | 59 | 2022 |
| Next‐generation disease modeling with direct conversion: a new path to old neurons L Traxler, F Edenhofer, J Mertens FEBS letters 593 (23), 3316-3337, 2019 | 58 | 2019 |
| Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease JR Herdy, L Traxler, RK Agarwal, L Karbacher, JCM Schlachetzki, ... Cell Stem Cell 29 (12), 1637-1652. e6, 2022 | 45 | 2022 |
| Presynaptic α2δ-2 calcium channel subunits regulate postsynaptic GABAA receptor abundance and axonal wiring S Geisler, CL Schöpf, R Stanika, M Kalb, M Campiglio, D Repetto, ... Journal of Neuroscience 39 (14), 2581-2605, 2019 | 42 | 2019 |
| Human neurons to model aging: a dish best served old L Böhnke, L Traxler, JR Herdy, J Mertens Drug Discovery Today: Disease Models 27, 43-49, 2018 | 20 | 2018 |
| Metabolism navigates neural cell fate in development, aging and neurodegeneration L Traxler, J Lagerwall, S Eichhorner, D Stefanoni, A D'Alessandro, ... Disease Models & Mechanisms 14 (8), dmm048993, 2021 | 19 | 2021 |
| Direct Conversion of Human Fibroblasts to Induced Neurons L Zhou-Yang, S Eichhorner, L Karbacher, L Böhnke, L Traxler, J Mertens Neural Reprogramming: Methods and Protocols, 73-96, 2021 | 6 | 2021 |
| Neural cell state shifts and fate loss in ageing and age-related diseases L Traxler, R Lucciola, JR Herdy, JR Jones, J Mertens, FH Gage Nature Reviews Neurology 19 (7), 434-443, 2023 | 5 | 2023 |
| Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile. Cell Rep 23: 2550–2558 Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ... | 5 | 2018 |
| Ignorance is bliss: Inhibition of proteomic stress sensing improves direct neuronal conversion L Traxler, O Borgogno, J Mertens Neuron 112 (7), 1035-1037, 2024 | | 2024 |
