When NRF2 talks, who's listening? N Wakabayashi, SL Slocum, JJ Skoko, S Shin, TW Kensler Antioxidants & redox signaling 13 (11), 1649-1663, 2010 | 641 | 2010 |
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid β secretion RP Koldamova, IM Lefterov, MD Ikonomovic, J Skoko, PI Lefterov, ... Journal of Biological Chemistry 278 (15), 13244-13256, 2003 | 297 | 2003 |
The benzo [c] phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1 A Vogt, A Tamewitz, J Skoko, RP Sikorski, KA Giuliano, JS Lazo Journal of Biological Chemistry 280 (19), 19078-19086, 2005 | 227 | 2005 |
Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling N Wakabayashi, JJ Skoko, DV Chartoumpekis, S Kimura, SL Slocum, ... Molecular and cellular biology 34 (4), 653-663, 2014 | 140 | 2014 |
Redox regulation of Cdc25B by cell-active quinolinediones M Brisson, T Nguyen, P Wipf, B Joo, BW Day, JS Skoko, EM Schreiber, ... Molecular pharmacology 68 (6), 1810-1820, 2005 | 104 | 2005 |
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet SL Slocum, JJ Skoko, N Wakabayashi, S Aja, M Yamamoto, TW Kensler, ... Archives of biochemistry and biophysics 591, 57-65, 2016 | 95 | 2016 |
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms DL Palliyaguru, DV Chartoumpekis, N Wakabayashi, JJ Skoko, ... Free Radical Biology and Medicine 101, 116-128, 2016 | 84 | 2016 |
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells A Vogt, PR McDonald, A Tamewitz, RP Sikorski, P Wipf, JJ Skoko III, ... Molecular cancer therapeutics 7 (2), 330-340, 2008 | 77 | 2008 |
Development and optimization of high-throughput in vitro protein phosphatase screening assays MB Tierno, PA Johnston, C Foster, JJ Skoko, SN Shinde, TY Shun, ... Nature protocols 2 (5), 1134-1144, 2007 | 74 | 2007 |
Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1 JS Lazo, R Nunes, JJ Skoko, PEQ de Oliveira, A Vogt, P Wipf Bioorganic & medicinal chemistry 14 (16), 5643-5650, 2006 | 71 | 2006 |
Peroxiredoxin involvement in the initiation and progression of human cancer MB Hampton, KA Vick, JJ Skoko, CA Neumann Antioxidants & redox signaling 28 (7), 591-608, 2018 | 69 | 2018 |
A peroxidase peroxiredoxin 1-specific redox regulation of the novel FOXO3 microRNA target let-7 BL Hopkins, M Nadler, JJ Skoko, T Bertomeu, A Pelosi, PM Shafaei, ... Antioxidants & redox signaling 28 (1), 62-77, 2018 | 64 | 2018 |
MKP-8, a novel MAPK phosphatase that inhibits p38 kinase SA Vasudevan, J Skoko, K Wang, SM Burlingame, PN Patel, JS Lazo, ... Biochemical and biophysical research communications 330 (2), 511-518, 2005 | 59 | 2005 |
Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B S Keinan, WD Paquette, JJ Skoko, DN Beratan, W Yang, S Shinde, ... Organic & Biomolecular Chemistry 6 (18), 3256-3263, 2008 | 56 | 2008 |
Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual … PA Johnston, CA Foster, TY Shun, JJ Skoko, S Shinde, P Wipf, JS Lazo Assay and drug development technologies 5 (3), 319-332, 2007 | 50 | 2007 |
Mimicking embedded vasculature structure for 3D cancer on a chip approaches through micromilling L Wan, J Skoko, J Yu, OB Ozdoganlar, PR LeDuc, CA Neumann Scientific reports 7 (1), 16724, 2017 | 40 | 2017 |
Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity JJ Skoko, N Wakabayashi, K Noda, S Kimura, K Tobita, N Shigemura, ... Toxicological Sciences 141 (1), 112-119, 2014 | 35 | 2014 |
Signals getting crossed in the entanglement of redox and phosphorylation pathways: phosphorylation of peroxiredoxin proteins sparks cell signaling JJ Skoko, S Attaran, CA Neumann Antioxidants 8 (2), 29, 2019 | 30 | 2019 |
Biological evaluation of newly synthesized quinoline-5, 8-quinones as Cdc25B inhibitors J Cossy, D Belotti, M Brisson, JJ Skoko, P Wipf, JS Lazo Bioorganic & medicinal chemistry 14 (18), 6283-6287, 2006 | 30 | 2006 |
Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library JS Lazo, JJ Skoko, S Werner, B Mitasev, A Bakan, F Koizumi, ... Journal of Pharmacology and Experimental Therapeutics 322 (3), 940-947, 2007 | 28 | 2007 |