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Lauren M. Slosky
Lauren M. Slosky
Bestätigte E-Mail-Adresse bei umn.edu - Startseite
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Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?
L Sanchez-Covarrubias, LM Slosky, BJ Thompson, TP Davis, ...
Current pharmaceutical design 20 (10), 1422-1449, 2014
2622014
Biased allosteric modulators: new frontiers in GPCR drug discovery
LM Slosky, MG Caron, LS Barak
Trends in pharmacological sciences 42 (4), 283-299, 2021
1082021
β-arrestin-biased allosteric modulator of NTSR1 selectively attenuates addictive behaviors
LM Slosky, Y Bai, K Toth, C Ray, LK Rochelle, A Badea, ...
Cell 181 (6), 1364-1379. e14, 2020
872020
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood–brain barrier: relevance to CNS drug delivery
BJ Thompson, L Sanchez-Covarrubias, LM Slosky, Y Zhang, ...
Journal of Cerebral Blood Flow & Metabolism 34 (4), 699-707, 2014
822014
Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor–dependent mechanism
LM Slosky, BJ Thompson, L Sanchez-Covarrubias, Y Zhang, ...
Molecular pharmacology 84 (5), 774-786, 2013
642013
Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation
SA Grenald, TM Doyle, H Zhang, LM Slosky, Z Chen, TM Largent-Milnes, ...
Pain 158 (9), 1733-1742, 2017
582017
Use of animal models in understanding cancer-induced bone pain
LM Slosky, TM Largent-Milnes, TW Vanderah
Cancer growth and metastasis 8, CGM. S21215, 2015
542015
Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain
BL Forte, LM Slosky, H Zhang, MR Arnold, WD Staatz, M Hay, ...
Pain 157 (12), 2709-2721, 2016
522016
P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac
L Sanchez-Covarrubias, LM Slosky, BJ Thompson, Y Zhang, ...
PloS one 9 (2), e88516, 2014
502014
The cystine/glutamate antiporter system xc− drives breast tumor cell glutamate release and cancer-induced bone pain
LM Slosky, NM BassiriRad, AM Symons, M Thompson, T Doyle, BL Forte, ...
Pain 157 (11), 2605-2616, 2016
402016
Discovery of β-arrestin biased, orally bioavailable, and CNS penetrant neurotensin receptor 1 (NTR1) allosteric modulators
AB Pinkerton, S Peddibhotla, F Yamamoto, LM Slosky, Y Bai, P Maloney, ...
Journal of medicinal chemistry 62 (17), 8357-8363, 2019
292019
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review
LM Slosky, TW Vanderah
Expert Opinion on Therapeutic Patents 25 (4), 443-466, 2015
252015
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
BE Krumm, JF DiBerto, RHJ Olsen, HJ Kang, ST Slocum, S Zhang, ...
Biochemistry 62 (7), 1233-1248, 2023
192023
A comparative study of the retention and lethality of the first and second generation arthropod protein markers
LM Slosky, EJ Hoffmann, JR Hagler
Entomologia Experimentalis et Applicata 144 (2), 165-171, 2012
162012
Ghrelin receptor antagonism of hyperlocomotion in cocaine‐sensitized mice requires βarrestin‐2
K Toth, LM Slosky, TF Pack, NM Urs, P Boone, L Mao, D Abraham, ...
Synapse 72 (1), e22012, 2018
122018
Encoding the β-arrestin trafficking fate of ghrelin receptor GHSR1a: C-tail-independent molecular determinants in GPCRs
K Toth, K Nagi, LM Slosky, L Rochelle, C Ray, S Kaur, SK Shenoy, ...
ACS Pharmacology & Translational Science 2 (4), 230-246, 2019
82019
Establishment of multi-stage intravenous self-administration paradigms in mice
LM Slosky, A Pires, Y Bai, NB Clark, ER Hauser, JD Gross, F Porkka, ...
Scientific reports 12 (1), 21422, 2022
72022
Discovery of a functionally selective ghrelin receptor (GHSR1a) ligand for modulating brain dopamine
JD Gross, DW Kim, Y Zhou, D Jansen, LM Slosky, NB Clark, CR Ray, ...
Proceedings of the National Academy of Sciences 119 (10), e2112397119, 2022
52022
Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens
SM Singhal, V Zell, L Faget, LM Slosky, LS Barak, MG Caron, ...
Neuropharmacology 234, 109544, 2023
22023
Prenatal heroin exposure alters brain morphology and connectivity in adolescent mice
KJ Hornburg, LM Slosky, G Cofer, J Cook, Y Qi, F Porkka, NB Clark, ...
NMR in Biomedicine 36 (2), e4842, 2023
22023
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