Roland Kolbeck
Roland Kolbeck
VP R&D, MedImmune/AZ; Assoc. Prof. McMaster University, Hamilton, Canada
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Cited by
Cited by
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?
M Kerschensteiner, E Gallmeier, L Behrens, VV Leal, T Misgeld, ...
The Journal of experimental medicine 189 (5), 865-870, 1999
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
L Schnell, R Schneider, R Kolbeck, YA Barde, ME Schwab
Nature 367 (6459), 170-173, 1994
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
M Sendtner, B Holtmann, R Kolbeck, H Thoenen, YA Barde
Nature 360 (6406), 757-759, 1992
MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
R Kolbeck, A Kozhich, M Koike, L Peng, CK Andersson, MM Damschroder, ...
Journal of allergy and clinical immunology 125 (6), 1344-1353. e2, 2010
Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study
M Castro, SE Wenzel, ER Bleecker, E Pizzichini, P Kuna, WW Busse, ...
The Lancet Respiratory Medicine 2 (11), 879-890, 2014
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia
M Laviolette, DL Gossage, G Gauvreau, R Leigh, R Olivenstein, R Katial, ...
Journal of allergy and clinical immunology 132 (5), 1086-1096. e5, 2013
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
T Matsumoto, S Rauskolb, M Polack, J Klose, R Kolbeck, M Korte, ...
Nature neuroscience 11 (2), 131-133, 2008
Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs
JS Silver, J Kearley, AM Copenhaver, C Sanden, M Mori, L Yu, ...
Nature immunology 17 (6), 626-635, 2016
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
WW Busse, R Katial, D Gossage, S Sari, B Wang, R Kolbeck, AJ Coyle, ...
Journal of Allergy and Clinical Immunology 125 (6), 1237-1244. e2, 2010
IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE
S Wang, J Wang, V Kumar, JL Karnell, B Naiman, PS Gross, S Rahman, ...
Nature communications 9 (1), 1758, 2018
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes
J Henault, J Martinez, JM Riggs, J Tian, P Mehta, L Clarke, M Sasai, ...
Immunity 37 (6), 986-997, 2012
IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization
DK Chu, A Llop-Guevara, TD Walker, K Flader, S Goncharova, ...
Journal of Allergy and Clinical Immunology 131 (1), 187-200. e8, 2013
Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity
M Canossa, O Griesbeck, B Berninger, G Campana, R Kolbeck, ...
Proceedings of the National Academy of Sciences 94 (24), 13279-13286, 1997
Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection
J Kearley, JS Silver, C Sanden, Z Liu, AA Berlin, N White, M Mori, ...
Immunity 42 (3), 566-579, 2015
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation
G Chen, R Kolbeck, YA Barde, T Bonhoeffer, A Kossel
Journal of Neuroscience 19 (18), 7983-7990, 1999
Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
N Ferhani, S Letuve, A Kozhich, O Thibaudeau, M Grandsaigne, M Maret, ...
American journal of respiratory and critical care medicine 181 (9), 917-927, 2010
Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kappa B …
HP Hohmann, M Brockhaus, PA Baeuerle, R Remy, R Kolbeck, ...
Journal of Biological Chemistry 265 (36), 22409-22417, 1990
Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model
SL Rowland, JM Riggs, S Gilfillan, M Bugatti, W Vermi, R Kolbeck, ...
Journal of Experimental Medicine 211 (10), 1977-1991, 2014
IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways
J Kearley, JS Erjefalt, C Andersson, E Benjamin, CP Jones, A Robichaud, ...
American journal of respiratory and critical care medicine 183 (7), 865-875, 2011
Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root
D Teupser, S Pavlides, M Tan, JC Gutierrez-Ramos, R Kolbeck, ...
Proceedings of the National Academy of Sciences 101 (51), 17795-17800, 2004
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