Mark Southern
Mark Southern
Bestätigte E-Mail-Adresse bei amgen.com - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry
Y Hamuro, SJ Coales, MR Southern, JF Nemeth-Cawley, DD Stranz, ...
Journal of biomolecular techniques: JBT 14 (3), 171, 2003
1762003
Hydrogen/deuterium‐exchange (H/D‐Ex) of PPARγ LBD in the presence of various modulators
Y Hamuro, SJ Coales, JA Morrow, KS Molnar, SJ Tuske, MR Southern, ...
Protein Science 15 (8), 1883-1892, 2006
1352006
Inforna 2.0: A platform for the sequence-based design of small molecules targeting structured RNAs
MD Disney, AM Winkelsas, SP Velagapudi, M Southern, M Fallahi, ...
ACS chemical biology 11 (6), 1720-1728, 2016
842016
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
BD Pascal, MJ Chalmers, SA Busby, CC Mader, MR Southern, ...
BMC bioinformatics 8 (1), 1-12, 2007
752007
BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets
SC Schürer, U Vempati, R Smith, M Southern, V Lemmon
Journal of biomolecular screening 16 (4), 415-426, 2011
572011
A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions
MJ Chalmers, SA Busby, BD Pascal, MR Southern, PR Griffin
Journal of biomolecular techniques: JBT 18 (4), 194, 2007
552007
Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho …
T Schröter, D Minond, A Weiser, C Dao, J Habel, T Spicer, P Chase, ...
Journal of biomolecular screening 13 (1), 17-28, 2008
542008
Studying a drug-like, RNA-focused small molecule library identifies compounds that inhibit RNA toxicity in myotonic dystrophy
SG Rzuczek, MR Southern, MD Disney
ACS chemical biology 10 (12), 2706-2715, 2015
472015
Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival
JW Chang, AM Zuhl, AE Speers, S Niessen, SJ Brown, MM Mulvihill, ...
ACS chemical biology 10 (4), 925-932, 2015
362015
PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem
SA Canny, Y Cruz, MR Southern, PR Griffin
Bioinformatics 28 (1), 140-141, 2012
352012
Design of a bioactive small molecule that targets r (AUUCU) repeats in spinocerebellar ataxia 10
WY Yang, R Gao, M Southern, PS Sarkar, MD Disney
Nature communications 7 (1), 1-11, 2016
302016
CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB–MYC involvement
AL Amelio, M Fallahi, FX Schaub, M Zhang, MB Lawani, AS Alperstein, ...
Proceedings of the National Academy of Sciences 111 (32), E3260-E3268, 2014
242014
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
EA Howe, A de Souza, DL Lahr, S Chatwin, P Montgomery, BR Alexander, ...
Nucleic acids research 43 (D1), D1163-D1170, 2015
222015
An overview of the challenges in designing, integrating, and delivering BARD: a public chemical-biology resource and query portal for multiple organizations, locations, and …
A De Souza, JA Bittker, DL Lahr, S Brudz, S Chatwin, TI Oprea, A Waller, ...
Journal of biomolecular screening 19 (5), 614-627, 2014
222014
A massively parallel selection of small molecule-RNA motif binding partners informs design of an antiviral from sequence
JL Childs-Disney, T Tran, BR Vummidi, SP Velagapudi, HS Haniff, ...
Chem 4 (10), 2384-2404, 2018
212018
Improved crystallographic structures using extensive combinatorial refinement
JC Nwachukwu, MR Southern, JR Kiefer, PV Afonine, PD Adams, ...
Structure 21 (11), 1923-1930, 2013
192013
Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice
C Girardet, M Mavrikaki, MR Southern, RG Smith, AA Butler
Endocrinology 155 (12), 4843-4855, 2014
182014
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
AT Pettersson-Klein, M Izadi, DMS Ferreira, I Cervenka, JC Correia, ...
Molecular metabolism 9, 28-42, 2018
172018
A Java API for working with PubChem datasets
MR Southern, PR Griffin
Bioinformatics 27 (5), 741-742, 2011
62011
JavaShade: multiple sequence alignment box-and-shading on the World Wide Web.
MR Southern, AP Lewis
Bioinformatics (Oxford, England) 14 (9), 821-822, 1998
61998
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