| Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry Y Hamuro, SJ Coales, MR Southern, JF Nemeth-Cawley, DD Stranz, ... Journal of biomolecular techniques: JBT 14 (3), 171, 2003 | 176 | 2003 |
| Hydrogen/deuterium‐exchange (H/D‐Ex) of PPARγ LBD in the presence of various modulators Y Hamuro, SJ Coales, JA Morrow, KS Molnar, SJ Tuske, MR Southern, ... Protein Science 15 (8), 1883-1892, 2006 | 135 | 2006 |
| Inforna 2.0: A platform for the sequence-based design of small molecules targeting structured RNAs MD Disney, AM Winkelsas, SP Velagapudi, M Southern, M Fallahi, ... ACS chemical biology 11 (6), 1720-1728, 2016 | 84 | 2016 |
| The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data BD Pascal, MJ Chalmers, SA Busby, CC Mader, MR Southern, ... BMC bioinformatics 8 (1), 1-12, 2007 | 75 | 2007 |
| BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets SC Schürer, U Vempati, R Smith, M Southern, V Lemmon Journal of biomolecular screening 16 (4), 415-426, 2011 | 57 | 2011 |
| A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions MJ Chalmers, SA Busby, BD Pascal, MR Southern, PR Griffin Journal of biomolecular techniques: JBT 18 (4), 194, 2007 | 55 | 2007 |
| Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho … T Schröter, D Minond, A Weiser, C Dao, J Habel, T Spicer, P Chase, ... Journal of biomolecular screening 13 (1), 17-28, 2008 | 54 | 2008 |
| Studying a drug-like, RNA-focused small molecule library identifies compounds that inhibit RNA toxicity in myotonic dystrophy SG Rzuczek, MR Southern, MD Disney ACS chemical biology 10 (12), 2706-2715, 2015 | 47 | 2015 |
| Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival JW Chang, AM Zuhl, AE Speers, S Niessen, SJ Brown, MM Mulvihill, ... ACS chemical biology 10 (4), 925-932, 2015 | 36 | 2015 |
| PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem SA Canny, Y Cruz, MR Southern, PR Griffin Bioinformatics 28 (1), 140-141, 2012 | 35 | 2012 |
| Design of a bioactive small molecule that targets r (AUUCU) repeats in spinocerebellar ataxia 10 WY Yang, R Gao, M Southern, PS Sarkar, MD Disney Nature communications 7 (1), 1-11, 2016 | 30 | 2016 |
| CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB–MYC involvement AL Amelio, M Fallahi, FX Schaub, M Zhang, MB Lawani, AS Alperstein, ... Proceedings of the National Academy of Sciences 111 (32), E3260-E3268, 2014 | 24 | 2014 |
| BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types EA Howe, A de Souza, DL Lahr, S Chatwin, P Montgomery, BR Alexander, ... Nucleic acids research 43 (D1), D1163-D1170, 2015 | 22 | 2015 |
| An overview of the challenges in designing, integrating, and delivering BARD: a public chemical-biology resource and query portal for multiple organizations, locations, and … A De Souza, JA Bittker, DL Lahr, S Brudz, S Chatwin, TI Oprea, A Waller, ... Journal of biomolecular screening 19 (5), 614-627, 2014 | 22 | 2014 |
| A massively parallel selection of small molecule-RNA motif binding partners informs design of an antiviral from sequence JL Childs-Disney, T Tran, BR Vummidi, SP Velagapudi, HS Haniff, ... Chem 4 (10), 2384-2404, 2018 | 21 | 2018 |
| Improved crystallographic structures using extensive combinatorial refinement JC Nwachukwu, MR Southern, JR Kiefer, PV Afonine, PD Adams, ... Structure 21 (11), 1923-1930, 2013 | 19 | 2013 |
| Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice C Girardet, M Mavrikaki, MR Southern, RG Smith, AA Butler Endocrinology 155 (12), 4843-4855, 2014 | 18 | 2014 |
| Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration AT Pettersson-Klein, M Izadi, DMS Ferreira, I Cervenka, JC Correia, ... Molecular metabolism 9, 28-42, 2018 | 17 | 2018 |
| A Java API for working with PubChem datasets MR Southern, PR Griffin Bioinformatics 27 (5), 741-742, 2011 | 6 | 2011 |
| JavaShade: multiple sequence alignment box-and-shading on the World Wide Web. MR Southern, AP Lewis Bioinformatics (Oxford, England) 14 (9), 821-822, 1998 | 6 | 1998 |
Bruce D. PascalOmics Informatics LLCBestätigte E-Mail-Adresse bei omicsinformatics.com
