Madeline Lancaster
Madeline Lancaster
MRC Laboratory of Molecular Biology
Verified email at - Homepage
Cited by
Cited by
Cerebral organoids model human brain development and microcephaly
MA Lancaster, M Renner, CA Martin, D Wenzel, LS Bicknell, ME Hurles, ...
Nature 501 (7467), 373-379, 2013
Organogenesis in a dish: modeling development and disease using organoid technologies
MA Lancaster, JA Knoblich
Science 345 (6194), 2014
Generation of cerebral organoids from human pluripotent stem cells
MA Lancaster, JA Knoblich
Nature protocols 9 (10), 2329-2340, 2014
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
JG Camp, F Badsha, M Florio, S Kanton, T Gerber, M Wilsch-Bräuninger, ...
Proceedings of the National Academy of Sciences 112 (51), 15672-15677, 2015
Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome
EM Valente, JL Silhavy, F Brancati, G Barrano, SR Krishnaswami, ...
Nature genetics 38 (6), 623-625, 2006
Guided self-organization and cortical plate formation in human brain organoids
MA Lancaster, NS Corsini, S Wolfinger, EH Gustafson, AW Phillips, ...
Nature biotechnology 35 (7), 659-666, 2017
Subcellular spatial regulation of canonical Wnt signalling at the primary cilium
MA Lancaster, J Schroth, JG Gleeson
Nature cell biology 13 (6), 700-707, 2011
Induction of expansion and folding in human cerebral organoids
Y Li, J Muffat, A Omer, I Bosch, MA Lancaster, M Sur, L Gehrke, ...
Cell stem cell 20 (3), 385-396. e3, 2017
Stem cell models of human brain development
I Kelava, MA Lancaster
Cell stem cell 18 (6), 736-748, 2016
Self‐organized developmental patterning and differentiation in cerebral organoids
M Renner, MA Lancaster, S Bian, H Choi, T Ku, A Peer, K Chung, ...
The EMBO journal 36 (10), 1316-1329, 2017
Cerebral organoids recapitulate epigenomic signatures of the human fetal brain
C Luo, MA Lancaster, R Castanon, JR Nery, JA Knoblich, JR Ecker
Cell reports 17 (12), 3369-3384, 2016
Dishing out mini-brains: current progress and future prospects in brain organoid research
I Kelava, MA Lancaster
Developmental biology 420 (2), 199-209, 2016
Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output
SL Giandomenico, SB Mierau, GM Gibbons, LMD Wenger, L Masullo, ...
Nature neuroscience 22 (4), 669-679, 2019
AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis
CM Louie, G Caridi, VS Lopes, F Brancati, A Kispert, MA Lancaster, ...
Nature genetics 42 (2), 175-180, 2010
Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy
MA Lancaster, CM Louie, JL Silhavy, L Sintasath, M DeCambre, ...
Nature medicine 15 (9), 1046-1054, 2009
The primary cilium as a cellular signaling center: lessons from disease
MA Lancaster, JG Gleeson
Current opinion in genetics & development 19 (3), 220-229, 2009
Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome
MA Lancaster, DJ Gopal, J Kim, SN Saleem, JL Silhavy, CM Louie, ...
Nature medicine 17 (6), 726-731, 2011
Spindle orientation in mammalian cerebral cortical development
MA Lancaster, JA Knoblich
Current opinion in neurobiology 22 (5), 737-746, 2012
Disease modelling in human organoids
MA Lancaster, M Huch
Disease models & mechanisms 12 (7), dmm039347, 2019
Non-model model organisms
JJ Russell, JA Theriot, P Sood, WF Marshall, LF Landweber, L Fritz-Laylin, ...
BMC biology 15 (1), 1-31, 2017
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