CIS is a potent checkpoint in NK cell–mediated tumor immunity RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ... Nature immunology 17 (7), 816-824, 2016 | 337 | 2016 |
Dysregulated IL-18 is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment K Nakamura, S Kassem, A Cleynen, ML Chretien, C Guillerey, EM Putz, ... Cancer cell 33 (4), 634-648. e5, 2018 | 182 | 2018 |
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy E Porpaczy, S Tripolt, A Hoelbl-Kovacic, B Gisslinger, Z Bago-Horvath, ... Blood, The Journal of the American Society of Hematology 132 (7), 694-706, 2018 | 152 | 2018 |
STAT5 is a key regulator in NK cells and acts as a molecular switch from tumor surveillance to tumor promotion D Gotthardt, EM Putz, E Grundschober, M Prchal-Murphy, E Straka, ... Cancer Discovery 6 (4), 414-429, 2016 | 141 | 2016 |
CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance EM Putz, D Gotthardt, G Hoermann, A Csiszar, S Wirth, A Berger, E Straka, ... Cell reports 4 (3), 437-444, 2013 | 133 | 2013 |
JAK/STAT cytokine signaling at the crossroad of NK cell development and maturation D Gotthardt, J Trifinopoulos, V Sexl, EM Putz Frontiers in immunology 10, 491611, 2019 | 132 | 2019 |
Interleukin-12 from CD103+ Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis D Mittal, D Vijayan, EM Putz, AR Aguilera, KA Markey, J Straube, ... Cancer immunology research 5 (12), 1098-1108, 2017 | 120 | 2017 |
Loss of STAT3 in murine NK cells enhances NK cell–dependent tumor surveillance D Gotthardt, EM Putz, E Straka, P Kudweis, M Biaggio, V Poli, B Strobl, ... Blood, The Journal of the American Society of Hematology 124 (15), 2370-2379, 2014 | 120 | 2014 |
NK cell heparanase controls tumor invasion and immune surveillance EM Putz, AJ Mayfosh, K Kos, DS Barkauskas, K Nakamura, L Town, ... The Journal of clinical investigation 127 (7), 2777-2788, 2017 | 106 | 2017 |
Bench to bedside: NK cells and control of metastasis Y Krasnova, EM Putz, MJ Smyth, F Souza-Fonseca-Guimaraes Clinical Immunology 177, 50-59, 2017 | 91 | 2017 |
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function B Salzer, CM Schueller, CU Zajc, T Peters, MA Schoeber, B Kovacic, ... Nature Communications 11 (1), 4166, 2020 | 68 | 2020 |
PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis A Berger, A Hoelbl-Kovacic, J Bourgeais, L Hoefling, W Warsch, ... Leukemia 28 (3), 629-641, 2014 | 66 | 2014 |
Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis EM Putz, C Guillerey, K Kos, K Stannard, K Miles, RB Delconte, K Takeda, ... Oncoimmunology 6 (2), e1267892, 2017 | 63 | 2017 |
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance T Mizutani, N Neugebauer, EM Putz, N Moritz, O Simma, ... Oncoimmunology 1 (7), 1027-1037, 2012 | 58 | 2012 |
In vivo long-term kinetics of radiolabeled N, N-dimethyltryptamine and tryptamine AA Vitale, AB Pomilio, CO Cañellas, MG Vitale, EM Putz, J Ciprian-Ollivier Journal of Nuclear Medicine 52 (6), 970-977, 2011 | 48 | 2011 |
The cooperating mutation or “second hit” determines the immunologic visibility toward MYC-induced murine lymphomas C Schuster, A Berger, MA Hoelzl, EM Putz, A Frenzel, O Simma, N Moritz, ... Blood, The Journal of the American Society of Hematology 118 (17), 4635-4645, 2011 | 46 | 2011 |
Leukemic challenge unmasks a requirement for PI3Kδ in NK cell–mediated tumor surveillance E Zebedin, O Simma, C Schuster, EM Putz, S Fajmann, W Warsch, ... Blood, The Journal of the American Society of Hematology 112 (12), 4655-4664, 2008 | 45 | 2008 |
NK Cell–Specific CDK8 deletion enhances antitumor responses A Witalisz-Siepracka, D Gotthardt, M Prchal-Murphy, Z Didara, I Menzl, ... Cancer immunology research 6 (4), 458-466, 2018 | 43 | 2018 |
PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes EM Putz, M Prchal-Murphy, OA Simma, F Forster, X Koenig, H Stockinger, ... PloS one 7 (7), e40852, 2012 | 35 | 2012 |
Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice P Pathria, D Gotthardt, M Prchal-Murphy, EM Putz, M Holcmann, ... Oncoimmunology 4 (4), e998529, 2015 | 34 | 2015 |