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Hepatitis B virus polymerase inhibits RIG-I-and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory … S Yu, J Chen, M Wu, H Chen, N Kato, Z Yuan Journal of General Virology 91 (8), 2080-2090, 2010 | 239 | 2010 |
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways Y Liu, J Li, J Chen, Y Li, W Wang, X Du, W Song, W Zhang, L Lin, Z Yuan Journal of virology 89 (4), 2287-2300, 2015 | 210 | 2015 |
An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases J Chen, W Zhang, J Lin, F Wang, M Wu, C Chen, Y Zheng, X Peng, J Li, ... Molecular Therapy 22 (2), 303-311, 2014 | 208 | 2014 |
Hepatitis B virus surface antigen selectively inhibits TLR2 ligand–induced IL-12 production in monocytes/macrophages by interfering with JNK activation S Wang, Z Chen, C Hu, F Qian, Y Cheng, M Wu, B Shi, J Chen, Y Hu, ... The Journal of Immunology 190 (10), 5142-5151, 2013 | 170 | 2013 |
PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation W Zhang, J Chen, M Wu, X Zhang, M Zhang, L Yue, Y Li, J Liu, B Li, ... Hepatology 66 (2), 398-415, 2017 | 137 | 2017 |
Hepatitis B virus polymerase impairs interferon‐α–induced STA T activation through inhibition of importin‐α5 and protein kinase C‐δ J Chen, M Wu, X Zhang, W Zhang, Z Zhang, L Chen, J He, Y Zheng, ... Hepatology 57 (2), 470-482, 2013 | 121 | 2013 |
Exosomes exploit the virus entry machinery and pathway to transmit alpha interferon-induced antiviral activity Z Yao, Y Qiao, X Li, J Chen, J Ding, L Bai, F Shen, B Shi, J Liu, L Peng, ... Journal of virology 92 (24), 10.1128/jvi. 01578-18, 2018 | 114 | 2018 |
Interferon and hepatitis B: current and future perspectives J Ye, J Chen Frontiers in Immunology 12, 733364, 2021 | 91 | 2021 |
Hepatitis B virus sensitivity to interferon‐α in hepatocytes is more associated with cellular interferon response than with viral genotype F Shen, Y Li, Y Wang, V Sozzi, PA Revill, J Liu, L Gao, G Yang, M Lu, ... Hepatology 67 (4), 1237-1252, 2018 | 66 | 2018 |
Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent population Z Yi, Y Ling, X Zhang, J Chen, K Hu, Y Wang, W Song, T Ying, R Zhang, ... Emerging microbes & infections 9 (1), 1988-1996, 2020 | 64 | 2020 |
Hepatitis B virus spliced variants are associated with an impaired response to interferon therapy J Chen, M Wu, F Wang, W Zhang, W Wang, X Zhang, J Zhang, Y Liu, ... Scientific reports 5 (1), 16459, 2015 | 62 | 2015 |
Label-free proteomic analysis of exosomes derived from inducible hepatitis B virus-replicating HepAD38 cell line X Jia, J Chen, DA Megger, X Zhang, M Kozlowski, L Zhang, Z Fang, J Li, ... Molecular & Cellular Proteomics 16 (4), S144-S160, 2017 | 55 | 2017 |
Low hepatitis B virus–specific T‐cell response in males correlates with high regulatory T‐cell numbers in murine models AD Kosinska, L Pishraft‐Sabet, W Wu, Z Fang, M Lenart, J Chen, ... Hepatology 66 (1), 69-83, 2017 | 52 | 2017 |
Functional comparison of interferon‐α subtypes reveals potent hepatitis B virus suppression by a concerted action of interferon‐α and interferon‐γ signaling J Chen, Y Li, F Lai, Y Wang, K Sutter, U Dittmer, J Ye, W Zai, M Liu, ... Hepatology 73 (2), 486-502, 2021 | 50 | 2021 |
AMPK and Akt/mTOR signalling pathways participate in glucose‐mediated regulation of hepatitis B virus replication and cellular autophagy X Wang, Y Lin, T Kemper, J Chen, Z Yuan, S Liu, Y Zhu, R Broering, M Lu Cellular Microbiology 22 (2), e13131, 2020 | 48 | 2020 |
Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection J Schuhenn, TL Meister, D Todt, T Bracht, K Schork, JN Billaud, C Elsner, ... Proceedings of the National Academy of Sciences 119 (8), e2111600119, 2022 | 40 | 2022 |
Label-free proteomic analysis of exosomes secreted from THP-1-derived macrophages treated with IFN-α identifies antiviral proteins enriched in exosomes Z Yao, X Jia, DA Megger, J Chen, Y Liu, J Li, B Sitek, Z Yuan Journal of proteome research 18 (3), 855-864, 2018 | 33 | 2018 |
New insights into hepatitis B virus biology and implications for novel antiviral strategies J Chen, M Wu, K Liu, W Zhang, Y Li, X Zhou, L Bai, Z Yuan National Science Review 2 (3), 296-313, 2015 | 31 | 2015 |