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Nikki Parker
Nikki Parker
Endocyte
Verified email at endocyte.com
Title
Cited by
Cited by
Year
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
N Parker, MJ Turk, E Westrick, JD Lewis, PS Low, CP Leamon
Analytical biochemistry 338 (2), 284-293, 2005
14062005
Synthesis and biological evaluation of EC20: a new folate-derived, 99mTc-based radiopharmaceutical
CP Leamon, MA Parker, IR Vlahov, LC Xu, JA Reddy, M Vetzel, ...
Bioconjugate chemistry 13 (6), 1200-1210, 2002
3342002
Preclinical evaluation of 99mTc-EC20 for imaging folate receptor–positive tumors
JA Reddy, LC Xu, N Parker, M Vetzel, CP Leamon
Journal of Nuclear Medicine 45 (5), 857-866, 2004
1562004
Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic
CP Leamon, JA Reddy, IR Vlahov, M Vetzel, N Parker, JS Nicoson, LC Xu, ...
Bioconjugate chemistry 16 (4), 803-811, 2005
1392005
Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145
CP Leamon, JA Reddy, IR Vlahov, E Westrick, N Parker, JS Nicoson, ...
International journal of cancer 121 (7), 1585-1592, 2007
1262007
Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue
CP Leamon, JA Reddy, M Vetzel, R Dorton, E Westrick, N Parker, Y Wang, ...
Cancer research 68 (23), 9839-9844, 2008
1232008
In vivo structural activity and optimization studies of folate− tubulysin conjugates
JA Reddy, R Dorton, A Dawson, M Vetzel, N Parker, JS Nicoson, ...
Molecular pharmaceutics 6 (5), 1518-1525, 2009
902009
Impact of high and low folate diets on tissue folate receptor levels and antitumor responses toward folate-drug conjugates
CP Leamon, JA Reddy, R Dorton, A Bloomfield, K Emsweller, N Parker, ...
Journal of Pharmacology and Experimental Therapeutics 327 (3), 918-925, 2008
822008
Targeting Folate Receptors to Treat Invasive Urinary Bladder Cancer
D Dhawan, JA Ramos-Vara, JF Naughton, L Cheng, PS Low, ...
Cancer Research, 2012
702012
Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications
CP Leamon, JA Reddy, PJ Klein, IR Vlahov, R Dorton, A Bloomfield, ...
Journal of Pharmacology and Experimental Therapeutics 336 (2), 336-343, 2011
622011
Preclinical evaluation of bispecific adaptor molecule controlled folate receptor CAR-T cell therapy with special focus on pediatric malignancies
YJ Lu, H Chu, LW Wheeler, M Nelson, E Westrick, JF Matthaei, II Cardle, ...
Frontiers in oncology 9, 151, 2019
512019
Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate–targeted immunotherapy in hapten-immunized mice
Y Lu, LC Xu, N Parker, E Westrick, JA Reddy, M Vetzel, PS Low, ...
Molecular cancer therapeutics 5 (12), 3258-3267, 2006
462006
Methods For Treating Cancer Using Combination Therapies
NL Parker, CP Leamon, IR Vlahov
US Patent App. 13/803,392, 2014
332014
Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease
KR Kipp, SL Kruger, MF Schimmel, N Parker, JM Shillingford, CP Leamon, ...
American Journal of Physiology-Renal Physiology 315 (2), F395-F405, 2018
322018
Antiinflammatory activity of a novel folic acid targeted conjugate of the mTOR inhibitor everolimus
Y Lu, N Parker, PJ Kleindl, VA Cross, K Wollak, E Westrick, TW Stinnette, ...
Molecular Medicine 21, 584-596, 2015
222015
Detecting functional and accessible folate receptor expression in cancer and polycystic kidneys
H Chu, JM Shillingford, JA Reddy, E Westrick, M Nelson, EZ Wang, ...
Molecular Pharmaceutics 16 (9), 3985-3995, 2019
72019
Combinatorial strategies of folate receptor-targeted chemotherapy guided by improved understanding of tumor microenvironment and immunomodulation
Y Lu, LW Wheeler, VA Cross, EM Westrick, AM Lloyd, TP Johnson, ...
Cancer Research 77 (13_Supplement), 4574-4574, 2017
22017
Tc-99m-EC20-A novel folate-derived radiopharmaceutical for cancer diagnostic imaging.
LC Xu, CP Leamon, MA Parker, IR Vlahov, JA Reddy, M Vetzel, ...
Journal of Nuclear Medicine 43 (5), 367P-367P, 2002
12002
Methods for treating cancer using combination therapies
NL Parker, CP Leamon, IR Vlahov
US Patent 10,010,618, 2018
2018
Treatment of epithelial ovarian cancer with folate receptor (α/β) targeted chemotherapy is enhanced by CTLA-4 blockade: Learning from animal models
Y Lu, TP Johnson, LW Wheeler, AM Lloyd, VA Cross, EM Westrick, ...
Cancer Research 77 (13_Supplement), 3670-3670, 2017
2017
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