|A conditional knockout resource for the genome-wide study of mouse gene function|
WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ...
Nature 474 (7351), 337-342, 2011
|Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system|
T Serafini, SA Colamarino, ED Leonardo, H Wang, R Beddington, ...
Cell 87 (6), 1001-1014, 1996
|An LDL-receptor-related protein mediates Wnt signalling in mice|
KI Pinson, J Brennan, S Monkley, BJ Avery, WC Skarnes
Nature 407 (6803), 535-538, 2000
|High-throughput discovery of novel developmental phenotypes|
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508-514, 2016
|Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects|
B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ...
Nature methods 11 (4), 399-402, 2014
|The knockout mouse project|
Nature genetics 36 (9), 921-924, 2004
|Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes|
A Gossler, AL Joyner, J Rossant, WC Skarnes
Science 244 (4903), 463-465, 1989
|Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes|
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
|Functional analysis of secreted and transmembrane proteins critical to mouse development|
KJ Mitchell, KI Pinson, OG Kelly, J Brennan, J Zupicich, P Scherz, ...
Nature genetics 28 (3), 241-249, 2001
|Defining brain wiring patterns and mechanisms through gene trapping in mice|
PA Leighton, KJ Mitchell, LV Goodrich, X Lu, K Pinson, P Scherz, ...
Nature 410 (6825), 174-179, 2001
|Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections|
H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, ...
Neuron 25 (1), 43-56, 2000
|Capturing genes encoding membrane and secreted proteins important for mouse development.|
WC Skarnes, JE Moss, SM Hurtley, RS Beddington
Proceedings of the National Academy of Sciences 92 (14), 6592-6596, 1995
|Agouti C57BL/6N embryonic stem cells for mouse genetic resources|
SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser, DR Beier, ...
Nature methods 6 (7), 493-495, 2009
|A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.|
WC Skarnes, BA Auerbach, AL Joyner
Genes & development 6 (6), 903-918, 1992
|ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a|
X Gao, P Tate, P Hu, R Tjian, WC Skarnes, Z Wang
Proceedings of the National Academy of Sciences 105 (18), 6656-6661, 2008
|The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice|
OG Kelly, KI Pinson, WC Skarnes
Oxford University Press for The Company of Biologists Limited 131 (12), 2803 …, 2004
|Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators|
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618-624, 2010
|The mammalian gene function resource: the International Knockout Mouse Consortium|
A Bradley, K Anastassiadis, A Ayadi, JF Battey, C Bell, MC Birling, ...
Mammalian genome 23, 580-586, 2012
|Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform|
C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016
|The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse|
P Tate, W Skarnes, A Bird
Nature genetics 12 (2), 205-208, 1996