William Skarnes
William Skarnes
Senior Group Leader, Wellcome Trust Sanger Institute
Bestätigte E-Mail-Adresse bei sanger.ac.uk - Startseite
TitelZitiert vonJahr
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
T Serafini, SA Colamarino, ED Leonardo, H Wang, R Beddington, ...
Cell 87 (6), 1001-1014, 1996
An LDL-receptor-related protein mediates Wnt signalling in mice
KI Pinson, J Brennan, S Monkley, BJ Avery, WC Skarnes
Nature 407 (6803), 535, 2000
A conditional knockout resource for the genome-wide study of mouse gene function
WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ...
Nature 474 (7351), 337, 2011
The knockout mouse project
CP Austin, JF Battey, A Bradley, M Bucan, M Capecchi, FS Collins, ...
Nature genetics 36 (9), 921, 2004
Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes
A Gossler, AL Joyner, J Rossant, WC Skarnes
Science 244 (4903), 463-465, 1989
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ...
Nature methods 11 (4), 399, 2014
Functional analysis of secreted and transmembrane proteins critical to mouse development
KJ Mitchell, KI Pinson, OG Kelly, J Brennan, J Zupicich, P Scherz, ...
Nature genetics 28 (3), 241, 2001
Defining brain wiring patterns and mechanisms through gene trapping in mice
PA Leighton, KJ Mitchell, LV Goodrich, X Lu, K Pinson, P Scherz, ...
Nature 410 (6825), 174, 2001
Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections
H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, ...
Neuron 25 (1), 43-56, 2000
Capturing genes encoding membrane and secreted proteins important for mouse development
WC Skarnes, JE Moss, SM Hurtley, RS Beddington
Proceedings of the National Academy of Sciences 92 (14), 6592-6596, 1995
A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.
WC Skarnes, BA Auerbach, AL Joyner
Genes & Development 6 (6), 903-918, 1992
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice
OG Kelly, KI Pinson, WC Skarnes
Development 131 (12), 2803-2815, 2004
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser, DR Beier, ...
Nature methods 6 (7), 493, 2009
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618, 2010
High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508, 2016
Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells
AL Joyner, WC Skarnes, J Rossant
Nature 338 (6211), 153, 1989
ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
X Gao, P Tate, P Hu, R Tjian, WC Skarnes, Z Wang
Proceedings of the National Academy of Sciences 105 (18), 6656-6661, 2008
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
D Stryke, M Kawamoto, CC Huang, SJ Johns, LA King, CA Harper, ...
Nucleic acids research 31 (1), 278-281, 2003
The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
P Tate, W Skarnes, A Bird
Nature genetics 12 (2), 205, 1996
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