William Skarnes
William Skarnes
Senior Group Leader, Wellcome Trust Sanger Institute
Bestätigte E-Mail-Adresse bei sanger.ac.uk - Startseite
TitelZitiert vonJahr
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
T Serafini, SA Colamarino, ED Leonardo, H Wang, R Beddington, ...
Cell 87 (6), 1001-1014, 1996
12381996
An LDL-receptor-related protein mediates Wnt signalling in mice
KI Pinson, J Brennan, S Monkley, BJ Avery, WC Skarnes
Nature 407 (6803), 535, 2000
11922000
A conditional knockout resource for the genome-wide study of mouse gene function
WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ...
Nature 474 (7351), 337, 2011
10192011
The knockout mouse project
CP Austin, JF Battey, A Bradley, M Bucan, M Capecchi, FS Collins, ...
Nature genetics 36 (9), 921, 2004
6002004
Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes
A Gossler, AL Joyner, J Rossant, WC Skarnes
Science 244 (4903), 463-465, 1989
5751989
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ...
Nature methods 11 (4), 399, 2014
5352014
Functional analysis of secreted and transmembrane proteins critical to mouse development
KJ Mitchell, KI Pinson, OG Kelly, J Brennan, J Zupicich, P Scherz, ...
Nature genetics 28 (3), 241, 2001
4212001
Defining brain wiring patterns and mechanisms through gene trapping in mice
PA Leighton, KJ Mitchell, LV Goodrich, X Lu, K Pinson, P Scherz, ...
Nature 410 (6825), 174, 2001
4052001
Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections
H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, ...
Neuron 25 (1), 43-56, 2000
3712000
Capturing genes encoding membrane and secreted proteins important for mouse development
WC Skarnes, JE Moss, SM Hurtley, RS Beddington
Proceedings of the National Academy of Sciences 92 (14), 6592-6596, 1995
3661995
A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.
WC Skarnes, BA Auerbach, AL Joyner
Genes & Development 6 (6), 903-918, 1992
3431992
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
2902013
The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice
OG Kelly, KI Pinson, WC Skarnes
Development 131 (12), 2803-2815, 2004
2842004
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser, DR Beier, ...
Nature methods 6 (7), 493, 2009
2812009
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ...
Nature cell biology 12 (6), 618, 2010
2652010
High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508, 2016
2632016
Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells
AL Joyner, WC Skarnes, J Rossant
Nature 338 (6211), 153, 1989
2601989
ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
X Gao, P Tate, P Hu, R Tjian, WC Skarnes, Z Wang
Proceedings of the National Academy of Sciences 105 (18), 6656-6661, 2008
2522008
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
D Stryke, M Kawamoto, CC Huang, SJ Johns, LA King, CA Harper, ...
Nucleic acids research 31 (1), 278-281, 2003
2512003
The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
P Tate, W Skarnes, A Bird
Nature genetics 12 (2), 205, 1996
2491996
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