| Mitochondrial function and morphology are impaired in parkin‐mutant fibroblasts H Mortiboys, KJ Thomas, WJH Koopman, S Klaffke, P Abou‐Sleiman, ... Annals of Neurology: Official Journal of the American Neurological …, 2008 | 424 | 2008 |
| Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss LS Tain, H Mortiboys, RN Tao, E Ziviani, O Bandmann, AJ Whitworth Nature neuroscience 12 (9), 1129-1135, 2009 | 352 | 2009 |
| Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2 H Mortiboys, KK Johansen, JO Aasly, O Bandmann Neurology 75 (22), 2017-2020, 2010 | 349 | 2010 |
| Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS) LE Cox, L Ferraiuolo, EF Goodall, PR Heath, A Higginbottom, H Mortiboys, ... PloS one 5 (3), e9872, 2010 | 297 | 2010 |
| Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio) L Flinn, H Mortiboys, K Volkmann, RW Köster, PW Ingham, O Bandmann Brain 132 (6), 1613-1623, 2009 | 213 | 2009 |
| Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically? R Macdonald, K Barnes, C Hastings, H Mortiboys Biochemical Society Transactions 46 (4), 891-909, 2018 | 177 | 2018 |
| Light affects mitochondria to cause apoptosis to cultured cells: possible relevance to ganglion cell death in certain optic neuropathies NN Osborne, GY Li, D Ji, HJ Mortiboys, S Jackson Journal of neurochemistry 105 (5), 2013-2028, 2008 | 137 | 2008 |
| Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation … M Keatinge, H Bui, A Menke, YC Chen, AM Sokol, Q Bai, F Ellett, ... Human molecular genetics 24 (23), 6640-6652, 2015 | 132 | 2015 |
| UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2G2019S carriers and in vivo H Mortiboys, R Furmston, G Bronstad, J Aasly, C Elliott, O Bandmann Neurology 85 (10), 846-852, 2015 | 127 | 2015 |
| Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson’s disease H Mortiboys, J Aasly, O Bandmann Brain 136 (10), 3038-3050, 2013 | 126 | 2013 |
| Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis SP Allen, S Rajan, L Duffy, H Mortiboys, A Higginbottom, AJ Grierson, ... Neurobiology of Aging 35 (6), 1499-1509, 2014 | 98 | 2014 |
| Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations C Liao, N Ashley, A Diot, K Morten, K Phadwal, A Williams, I Fearnley, ... Neurology 88 (2), 131-142, 2017 | 95 | 2017 |
| TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency LJ Flinn, M Keatinge, S Bretaud, H Mortiboys, H Matsui, E De Felice, ... Annals of neurology 74 (6), 837-847, 2013 | 95 | 2013 |
| Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1−/− zebrafish S Soman, M Keatinge, M Moein, M Da Costa, H Mortiboys, A Skupin, ... European Journal of Neuroscience 45 (4), 528-535, 2017 | 88 | 2017 |
| Modulating mitophagy in mitochondrial disease E Dombi, H Mortiboys, J Poulton Current medicinal chemistry 25 (40), 5597-5612, 2018 | 80 | 2018 |
| The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy JH Pogson, RM Ivatt, A Sanchez-Martinez, R Tufi, E Wilson, H Mortiboys, ... PLoS genetics 10 (11), e1004815, 2014 | 78 | 2014 |
| Ursodeoxycholic acid improves mitochondrial function and redistributes Drp1 in fibroblasts from patients with either sporadic or familial Alzheimer's disease SM Bell, K Barnes, H Clemmens, AR Al-Rafiah, EA Al-Ofi, V Leech, ... Journal of molecular biology 430 (21), 3942-3953, 2018 | 77 | 2018 |
| Mitochondrial dysfunction in Alzheimer’s disease: a biomarker of the future? SM Bell, K Barnes, M De Marco, PJ Shaw, L Ferraiuolo, DJ Blackburn, ... Biomedicines 9 (1), 63, 2021 | 76 | 2021 |
| USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation EV Rusilowicz-Jones, J Jardine, A Kallinos, A Pinto-Fernandez, ... Life science alliance 3 (8), 2020 | 71 | 2020 |
| C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis SP Allen, B Hall, R Woof, L Francis, N Gatto, AC Shaw, M Myszczynska, ... Brain 142 (12), 3771-3790, 2019 | 70 | 2019 |
