Nrf2 regulates ROS production by mitochondria and NADPH oxidase S Kovac, PR Angelova, KM Holmström, Y Zhang, AT Dinkova-Kostova, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015 | 444 | 2015 |
Role of mitochondrial ROS in the brain: from physiology to neurodegeneration PR Angelova, AY Abramov FEBS letters 592 (5), 692-702, 2018 | 410 | 2018 |
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, ... Nature communications 9 (1), 1-16, 2018 | 283 | 2018 |
Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, ... Antioxidants & redox signaling 24 (7), 376-391, 2016 | 268 | 2016 |
Functional oxygen sensitivity of astrocytes PR Angelova, V Kasymov, I Christie, S Sheikhbahaei, E Turovsky, ... Journal of Neuroscience 35 (29), 10460-10473, 2015 | 223 | 2015 |
Nrf2 affects the efficiency of mitochondrial fatty acid oxidation MHR Ludtmann, PR Angelova, Y Zhang, AY Abramov, ... Biochemical Journal 457 (3), 415-424, 2014 | 195 | 2014 |
Functional role of mitochondrial reactive oxygen species in physiology PR Angelova, AY Abramov Free radical biology and medicine 100, 81-85, 2016 | 179 | 2016 |
Ca2+ is a key factor in α-synuclein-induced neurotoxicity PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, ... Journal of cell science 129 (9), 1792-1801, 2016 | 147 | 2016 |
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, ... Cell death & disease 6 (7), e1820-e1820, 2015 | 137 | 2015 |
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 136 | 2015 |
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease R Tufi, S Gandhi, IP De Castro, S Lehmann, PR Angelova, D Dinsdale, ... Nature cell biology 16 (2), 157-166, 2014 | 133 | 2014 |
Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury HK Siddall, DM Yellon, SB Ong, UA Mukherjee, N Burke, AR Hall, ... PloS one 8 (4), e62400, 2013 | 125 | 2013 |
Monomeric alpha-synuclein exerts a physiological role on brain ATP synthase MHR Ludtmann, PR Angelova, NN Ninkina, S Gandhi, VL Buchman, ... Journal of Neuroscience 36 (41), 10510-10521, 2016 | 122 | 2016 |
Lipid peroxidation is essential for α‐synuclein‐induced cell death PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, ... Journal of neurochemistry 133 (4), 582-589, 2015 | 113 | 2015 |
Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation PR Angelova, M Barilani, C Lovejoy, M Dossena, M Viganò, A Seresini, ... Redox biology 14, 474-484, 2018 | 96 | 2018 |
'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia' R Abeti, MH Parkinson, IP Hargreaves, PR Angelova, C Sandi, MA Pook, ... Cell death & disease 7 (5), e2237-e2237, 2016 | 93 | 2016 |
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, ... Cell Death & Differentiation 27 (10), 2781-2796, 2020 | 76 | 2020 |
Mutations in HPCA cause autosomal-recessive primary isolated dystonia G Charlesworth, PR Angelova, F Bartolomé-Robledo, M Ryten, ... The American Journal of Human Genetics 96 (4), 657-665, 2015 | 76 | 2015 |
Interaction of neurons and astrocytes underlies the mechanism of Aβ-induced neurotoxicity PR Angelova, AY Abramov Biochemical Society Transactions 42 (5), 1286-1290, 2014 | 75 | 2014 |
Alpha-synuclein and beta-amyloid–different targets, same players: calcium, free radicals and mitochondria in the mechanism of neurodegeneration PR Angelova, AY Abramov Biochemical and biophysical research communications 483 (4), 1110-1115, 2017 | 72 | 2017 |