Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase: steps toward novel drugs for treating Alzheimer's disease YP Pang, P Quiram, T Jelacic, F Hong, S Brimijoin Journal of Biological Chemistry 271 (39), 23646-23649, 1996 | 529 | 1996 |
Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse B Li, JA Stribley, A Ticu, W Xie, LM Schopfer, P Hammond, S Brimijoin, ... Journal of neurochemistry 75 (3), 1320-1331, 2000 | 452 | 2000 |
Axonal transport of substance P in the vagus and sciatic nerves of the guinea pig S Brimijoin, JM Lundberg, E Brodin, T Ho Brain Research 191 (2), 443-457, 1980 | 336 | 1980 |
Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex T Rees, PI Hammond, H Soreq, S Younkin, S Brimijoin Neurobiology of aging 24 (6), 777-787, 2003 | 287 | 2003 |
Molecular forms of acetylcholinesterase in brain, nerve and muscle: nature, localization and dynamics S Brimijoin Progress in neurobiology 21 (4), 291-322, 1983 | 254 | 1983 |
Neurally mediated increase in dopamine-β-hydroxylase activity PB Molinoff, S Brimijoin, R Weinshilboum, J Axelrod Proceedings of the National Academy of Sciences 66 (2), 453-458, 1970 | 209 | 1970 |
1, 25-Dihydroxyvitamin D3 receptors in the central nervous system of the rat embryo TD Veenstra, K Prüfer, C Koenigsberger, SW Brimijoin, JP Grande, ... Brain research 804 (2), 193-205, 1998 | 206 | 1998 |
Retrograde axonal transport of transmitter enzymes, fucose-labeled protein, and nerve growth factor in streptozotocin-diabetic rats J Jakobsen, S Brimijoin, K Skau, P Sidenius, D Wells Diabetes 30 (10), 797-803, 1981 | 193 | 1981 |
Re-engineering butyrylcholinesterase as a cocaine hydrolase H Sun, YP Pang, O Lockridge, S Brimijoin Molecular pharmacology 62 (2), 220-224, 2002 | 174 | 2002 |
The role of acetylcholinesterase in the pathogenesis of Alzheimer's disease. TM Rees, S Brimijoin Drugs of today (Barcelona, Spain: 1998) 39 (1), 75-83, 2003 | 167 | 2003 |
Peripheral peptide neurons: distribution, axonal transport, and some aspects on possible function JM Lundberg, T Hökfelt, A Anggård, K Uvnäs-Wallensten, S Brimijoin, ... Advances in biochemical psychopharmacology 22, 25-36, 1980 | 157 | 1980 |
A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats S Brimijoin, Y Gao, JJ Anker, LA Gliddon, D LaFleur, R Shah, Q Zhao, ... Neuropsychopharmacology 33 (11), 2715-2725, 2008 | 155 | 2008 |
Neurite differentiation is modulated in neuroblastoma cells engineered for altered acetylcholinesterase expression C Koenigsberger, S Chiappa, S Brimijoin Journal of neurochemistry 69 (4), 1389-1397, 1997 | 151 | 1997 |
Cholinesterases in neural development: new findings and toxicologic implications. S Brimijoin, C Koenigsberger Environmental health perspectives 107 (suppl 1), 59-64, 1999 | 149 | 1999 |
Ischemic conduction failure and energy metabolism in experimental diabetic neuropathy PA Low, K Ward, JD Schmelzer, S Brimijoin American Journal of Physiology-Endocrinology and Metabolism 248 (4), E457-E462, 1985 | 142 | 1985 |
Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators YP Pang, TM Kollmeyer, F Hong, JC Lee, PI Hammond, SP Haugabouk, ... Chemistry & biology 10 (6), 491-502, 2003 | 139 | 2003 |
Cholinesterases and the fine line between poison and remedy CN Pope, S Brimijoin Biochemical pharmacology 153, 205-216, 2018 | 134 | 2018 |
Plasma butyrylcholinesterase regulates ghrelin to control aggression VP Chen, Y Gao, L Geng, RJ Parks, YP Pang, S Brimijoin Proceedings of the National Academy of Sciences 112 (7), 2251-2256, 2015 | 127 | 2015 |
Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos TL Lassiter, S Brimijoin Neurotoxicology and teratology 30 (2), 125-130, 2008 | 121 | 2008 |
Comparison of thein VitroSensitivity of rat acetylcholinesterase to chlorpyrifos-oxon: What do tissue IC50 values represent? SR Mortensen, S Brimijoin, MJ Hooper, S Padilla Toxicology and applied pharmacology 148 (1), 46-49, 1998 | 120 | 1998 |