Weng Khong Lim
Weng Khong Lim
Chief Information Officer, SingHealth Duke-NUS Institute of Precision Medicine
Bestätigte E-Mail-Adresse bei duke-nus.edu.sg - Startseite
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Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
W Chan-On, ML Nairismägi, CK Ong, WK Lim, S Dima, C Pairojkul, ...
Nature genetics 45 (12), 1474, 2013
3482013
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer discovery 7 (10), 1116-1135, 2017
2802017
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool
SL Poon, ST Pang, JR McPherson, W Yu, KK Huang, P Guan, WH Weng, ...
Science translational medicine 5 (197), 197ra101-197ra101, 2013
2382013
Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma
WK Lim, CK Ong, J Tan, AA Thike, CCY Ng, V Rajasegaran, SS Myint, ...
Nature genetics 46 (8), 877-880, 2014
1652014
Genomic landscapes of breast fibroepithelial tumors
J Tan, CK Ong, WK Lim, CCY Ng, AA Thike, LM Ng, V Rajasegaran, ...
Nature genetics 47 (11), 1341-1345, 2015
1322015
Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
LD Ler, S Ghosh, X Chai, AA Thike, HL Heng, EY Siew, S Dey, LK Koh, ...
Science translational medicine 9 (378), 2017
1052017
The DNA structure-specific endonuclease MUS81 mediates DNA sensor STING-dependent host rejection of prostate cancer cells
SSW Ho, WYL Zhang, NYJ Tan, M Khatoo, MA Suter, S Tripathi, ...
Immunity 44 (5), 1177-1189, 2016
1042016
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 1-17, 2019
942019
Prediction of human population responses to toxic compounds by a collaborative competition
F Eduati, LM Mangravite, T Wang, H Tang, JC Bare, R Huang, T Norman, ...
Nature biotechnology 33 (9), 933-940, 2015
912015
JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma
ML Nairismägi, J Tan, JQ Lim, S Nagarajan, CCY Ng, V Rajasegaran, ...
Leukemia 30 (6), 1311-1319, 2016
872016
The draft genome of tropical fruit durian (Durio zibethinus)
BT Teh, K Lim, CH Yong, CCY Ng, SR Rao, V Rajasegaran, WK Lim, ...
Nature genetics 49 (11), 1633-1641, 2017
852017
Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.
E Diffner, D Beck, E Gudgin, JA Thoms, K Knezevic, C Pridans, S Foster, ...
Blood, 2013
662013
Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance
AL Vettore, K Ramnarayanan, G Poore, K Lim, CK Ong, KK Huang, ...
Genome medicine 7 (1), 1-15, 2015
602015
MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases
CCY Ng, J Tan, CK Ong, WK Lim, V Rajasegaran, NDM Nasir, JCT Lim, ...
Journal of clinical pathology 68 (9), 685-691, 2015
522015
An eleven gene molecular signature for extra-capsular spread in oral squamous cell carcinoma serves as a prognosticator of outcome in patients without nodal metastases
W Wang, WK Lim, HS Leong, FT Chong, TKH Lim, DSW Tan, BT Teh, ...
Oral oncology 51 (4), 355-362, 2015
432015
Germline mutations in cancer predisposition genes are frequent in sporadic sarcomas
SH Chan, WK Lim, NDB Ishak, ST Li, WL Goh, G San Tan, KH Lim, M Teo, ...
Scientific reports 7 (1), 1-8, 2017
412017
Beyond fitness tracking: the use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research
WK Lim, S Davila, JX Teo, C Yang, CJ Pua, C Blöcker, JQ Lim, J Ching, ...
PLoS biology 16 (2), e2004285, 2018
382018
Large-scale whole-genome sequencing of three diverse Asian populations in Singapore
D Wu, J Dou, X Chai, C Bellis, A Wilm, CC Shih, WWJ Soon, N Bertin, ...
Cell 179 (3), 736-749. e15, 2019
302019
Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways
S Kongpetch, A Jusakul, CK Ong, WK Lim, SG Rozen, P Tan, BT Teh
Best Practice & Research Clinical Gastroenterology 29 (2), 233-244, 2015
272015
CD1d expression in renal cell carcinoma is associated with higher relapse rates, poorer cancer-specific and overall survival
TW Chong, FY Goh, MY Sim, HH Huang, DAA Thike, WK Lim, BT Teh, ...
Journal of clinical pathology 68 (3), 200-205, 2015
242015
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