Bruce Kennedy Cassels
Bruce Kennedy Cassels
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Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host
JD Maya, BK Cassels, P Iturriaga-Vásquez, J Ferreira, M Faúndez, ...
Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2007
α4β2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine
M Moroni, R Zwart, E Sher, BK Cassels, I Bermudez
Molecular pharmacology 70 (2), 755-768, 2006
Plant metabolites active against Trypanosoma cruzi
S Sepúlveda-Boza, BK Cassels
Planta Medica 62 (02), 98-105, 1996
Topical anti-inflammatory activity of 2α-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae
MC Aguirre, C Delporte, N Backhouse, S Erazo, ME Letelier, BK Cassels, ...
Bioorganic & medicinal chemistry 14 (16), 5673-5677, 2006
Boldo and boldine: an emerging case of natural drug development
H Speisky, BK Cassels
Pharmacological Research 29 (1), 1-12, 1994
Anti-inflammatory and antipyretic effects of boldine
N Backhouse, C Delporte, M Givernau, BK Cassels, A Valenzuela, ...
Agents and Actions 42 (3), 114-117, 1994
Chilenine: an isoindolobenzazepine alkaloid
V Fajardo, V Elango, BK Cassels, M Shamma
Tetrahedron Letters 23 (1), 39-42, 1982
Glutathione transferase M2-2 catalyzes conjugation of dopamine and dopa o-quinones
A Dagnino-Subiabre, BK Cassels, S Baez, AS Johansson, B Mannervik, ...
Biochemical and biophysical research communications 274 (1), 32-36, 2000
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT) 2A and 5-HT2C receptors
PR Moya, KA Berg, MA Gutierrez-Hernandez, P Saez-Briones, ...
Journal of Pharmacology and Experimental Therapeutics 321 (3), 1054-1061, 2007
Revision of the early steps of reticuline biosynthesis
R Stadler, TM Kutchan, S Loeffler, N Nagakura, B Cassels, MH Zenk
Tetrahedron letters 28 (12), 1251-1254, 1987
6-Bromoflavone, a high affinity ligand for the central benzodiazepine receptors is a member of a family of active flavonoids
M Marder, H Viola, C Wasowski, C Wolfman, PG Waterman, BK Cassels, ...
Biochemical and biophysical research communications 223 (2), 384-389, 1996
Monoamine oxidase inhibitory properties of some methoxylated and alkylthio amphetamine derivatives: structure–activity relationships
MC Scorza, C Carrau, R Silveira, G Zapata-Torres, BK Cassels, ...
Biochemical pharmacology 54 (12), 1361-1369, 1997
From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research
BK Cassels, I Bermúdez, F Dajas, JA Abin-Carriquiry, S Wonnacott
Drug discovery today 10 (23-24), 1657-1665, 2005
Antioxidant properties of the alkaloid boldine in systems undergoing lipid peroxidation and enzyme inactivation
H Speisky, BK Cassels, EA Lissi, LA Videla
Biochemical pharmacology 41 (11), 1575-1581, 1991
Halogenated cytisine derivatives as agonists at human neuronal nicotinic acetylcholine receptor subtypes
YE Slater, LM Houlihan, PD Maskell, R Exley, I Bermúdez, RJ Lukas, ...
Neuropharmacology 44 (4), 503-515, 2003
Sulfur-substituted α-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling
A Gallardo-Godoy, A Fierro, TH McLean, M Castillo, BK Cassels, ...
Journal of medicinal chemistry 48 (7), 2407-2419, 2005
Inhibitory effect of boldine on fish oil oxidation
A Valenzuela, S Nieto, BK Cassels, H Speisky
Journal of the American Oil Chemists' Society 68 (12), 935-937, 1991
Active constituents isolated from Psoralea glandulosa L. with antiinflammatory and antipyretic activities
CN Backhouse, CL Delporte, RE Negrete, S Erazo, A Zuñiga, A Pinto, ...
Journal of ethnopharmacology 78 (1), 27-31, 2001
Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5‐HT2A and 5‐HT2C receptors
C Acuña‐Castillo, C Villalobos, PR Moya, P Sáez, BK Cassels, ...
British Journal of Pharmacology 136 (4), 510-519, 2002
Activity of cytisine and its brominated isosteres on recombinant human α7, α4β2 and α4β4 nicotinic acetylcholine receptors
LM Houlihan, Y Slater, DL Guerra, JH Peng, YP Kuo, RJ Lukas, ...
Journal of neurochemistry 78 (5), 1029-1043, 2001
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