EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvà, ... Cancer cell 26 (5), 668-681, 2014 | 411 | 2014 |
Cancer-specific retargeting of BAF complexes by a prion-like domain G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ... Cell 171 (1), 163-178. e19, 2017 | 388 | 2017 |
The transcription factor encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome biology 13, 1-25, 2012 | 130 | 2012 |
Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells C Van Rechem, G Boulay, S Pinte, N Stankovic-Valentin, C Guérardel, ... Molecular and cellular biology 30 (16), 4045-4059, 2010 | 118 | 2010 |
HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors C Fleuriel, M Touka, G Boulay, C Guérardel, BR Rood, D Leprince The international journal of biochemistry & cell biology 41 (1), 26-33, 2009 | 110 | 2009 |
Binding of TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis GJ Sandoval, JL Pulice, H Pakula, M Schenone, DY Takeda, M Pop, ... Molecular cell 71 (4), 554-566. e7, 2018 | 94 | 2018 |
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma L Jerby-Arnon, C Neftel, ME Shore, HR Weisman, ND Mathewson, ... Nature medicine 27 (2), 289-300, 2021 | 74 | 2021 |
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies G Boulay, A Volorio, S Iyer, LC Broye, I Stamenkovic, N Riggi, MN Rivera Genes & development 32 (15-16), 1008-1019, 2018 | 67 | 2018 |
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A C Van Rechem, G Boulay, D Leprince Biochemical and biophysical research communications 385 (4), 586-590, 2009 | 59 | 2009 |
OTX2 activity at distal regulatory elements shapes the chromatin landscape of group 3 medulloblastoma G Boulay, ME Awad, N Riggi, TC Archer, S Iyer, WE Boonseng, ... Cancer discovery 7 (3), 288-301, 2017 | 58 | 2017 |
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins G Boulay, M Dubuissez, C Van Rechem, A Forget, K Helin, O Ayrault, ... Journal of Biological Chemistry 287 (13), 10509-10524, 2012 | 52 | 2012 |
Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 protein complexes G Boulay, C Rosnoblet, C Guérardel, PO Angrand, D Leprince Biochemical Journal 434 (2), 333-342, 2011 | 49 | 2011 |
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways SM Rothenberg, K Concannon, S Cullen, G Boulay, AB Turke, AC Faber, ... Elife 4, e06132, 2015 | 47 | 2015 |
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis Y Zheng, V Comaills, R Burr, G Boulay, DT Miyamoto, BS Wittner, ... Proceedings of the National Academy of Sciences 116 (12), 5223-5232, 2019 | 46 | 2019 |
Loss of Hypermethylated in Cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through β-2 adrenergic receptor (ADRB2) misregulation G Boulay, N Malaquin, I Loison, B Foveau, C Van Rechem, BR Rood, ... Journal of Biological Chemistry 287 (8), 5379-5389, 2012 | 42 | 2012 |
The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1) B Foveau, G Boulay, S Pinte, C Van Rechem, BR Rood, D Leprince Journal of Biological Chemistry 287 (8), 5366-5378, 2012 | 36 | 2012 |
LIN28B underlies the pathogenesis of a subclass of Ewing sarcoma T Keskin, A Bakaric, P Waszyk, G Boulay, M Torsello, S Cornaz-Buros, ... Cell reports 30 (13), 4567-4583. e5, 2020 | 27 | 2020 |
Identification of p21 (CIP1/WAF1) as a direct target gene of HIC1 (Hypermethylated In Cancer 1) V Dehennaut, I Loison, G Boulay, C Van Rechem, D Leprince Biochemical and biophysical research communications 430 (1), 49-53, 2013 | 26 | 2013 |
EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma E Möller, V Praz, S Rajendran, R Dong, A Cauderay, YH Xing, L Lee, ... Nature Communications 13 (1), 2267, 2022 | 22 | 2022 |
Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression I Sanidas, H Lee, PH Rumde, G Boulay, R Morris, G Golczer, M Stanzione, ... Molecular cell 82 (18), 3333-3349. e9, 2022 | 17 | 2022 |