Bruce S. Kristal

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Rima Kaddurah-DaoukProfessorVerified email at mc.duke.edu
Wayne Matsonchief scientist co-founder Ixcela Inc.Verified email at ixcela.com
Robert M FriedlanderUniversity of PittsburghVerified email at upmc.edu
Vasant R. MarurDiv. of Sleep & Circadian Disorders, Dept. of Medicine, Brigham and Women's Hospital, Boston, MAVerified email at bwh.harvard.edu
M. Flint BealProfessor of Neurology, Weill CornellVerified email at med.cornell.edu
Oliver FiehnUC DavisVerified email at ucdavis.edu
Ben van OmmenPrincipal Scientist, TNOVerified email at tno.nl
Rose Muthoni GathunguEuropean Biology Molecular LaboratoryVerified email at embl.de
Roy GoodacreDepartment of Biochemistry and Systems Biology, ISMIB, University of LiverpoolVerified email at liverpool.ac.uk
Loic Le MarchandProfessor of Epidemiology, University of Hawaii Cancer CenterVerified email at cc.hawaii.edu
Lloyd W. SumnerUniversity of Missouri, Biochemistry Dept, Christopher S. Bond Life Sciences Center, MU MetabolomicsVerified email at missouri.edu
Susanna-Assunta SansoneUniversity of Oxford, Professor of Data Readiness; Oxford e-Research Centre, Associate Director.Verified email at oerc.ox.ac.uk
James MitchellAssociate Professor of Genetics and Complex Diseases, Harvard T. H. Chan School of Public HealthVerified email at hsph.harvard.edu
C. Keith Ozaki, MDBrigham and Women's Hospital/Harvard Medical SchoolVerified email at partners.org
Pedro MendesUniversity of ConnecticutVerified email at uchc.edu
Mariët van der WerfGlobal Platform DirectorVerified email at hetnet.nl
Griffin JLUniversity of CambridgeVerified email at cam.ac.uk
Norman MorrisonResearch Fellow, School of Computer Science, University of ManchesterVerified email at manchester.ac.uk
Steven GullansVerified email at excelvm.com
Betty Y.S. Kim, MD, PhD, CIP, FRCSCMD Anderson Cancer CenterVerified email at mdanderson.org

Bruce S. Kristal

Assoc Prof, Div Sleep/Circadian Disorders, Dept Medicine, Brigham and Women's Hospital + Harvard Med

Verified email at partners.org

metabolomics lipidomics informatics biomarkers mitochondria


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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice S Zhu, IG Stavrovskaya, M Drozda, B Kim, V Ona, M Li, S Sarang, AS Liu, ... Nature 417 (6884), 74-78, 2002	1241	2002
Metabolomics: a global biochemical approach to drug response and disease R Kaddurah-Daouk, BS Kristal, RM Weinshilboum Annu. Rev. Pharmacol. Toxicol. 48, 653-683, 2008	745	2008
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research A Scalbert, L Brennan, O Fiehn, T Hankemeier, BS Kristal, B van Ommen, ... Metabolomics 5 (4), 435-458, 2009	579	2009
Minocycline inhibits caspase-independent and-dependent mitochondrial cell death pathways in models of Huntington's disease X Wang, S Zhu, M Drozda, W Zhang, IG Stavrovskaya, E Cattaneo, ... Proceedings of the National Academy of Sciences 100 (18), 10483-10487, 2003	489	2003
Proposed minimum reporting standards for data analysis in metabolomics R Goodacre, D Broadhurst, AK Smilde, BS Kristal, JD Baker, R Beger, ... Metabolomics 3 (3), 231-241, 2007	457	2007
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease TS Tang, E Slow, V Lupu, IG Stavrovskaya, M Sugimori, R Llinás, ... Proceedings of the National Academy of Sciences 102 (7), 2602-2607, 2005	454	2005
The metabolomics standards initiative (MSI) O Fiehn, D Robertson, J Griffin, M van der Werf, B Nikolau, N Morrison, ... Metabolomics 3 (3), 175-178, 2007	383	2007
Multiple roles of glutathione in the central nervous system AJL Cooper, BS Kristal Biological Chemistry-Hoppe Seyler 378 (8), 793-802, 1997	375	1997
An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions BS Kristal, BP Yu Journal of Gerontology 47 (4), B107-B114, 1992	294	1992
4-Hydroxyhexenal Is a Potent Inducer of the Mitochondrial Permeability Transition (∗) BS Kristal, BK Park, PY Byung Journal of Biological Chemistry 271 (11), 6033-6038, 1996	290	1996
High‐throughput profiling of the mitochondrial proteome using affinity fractionation and automation MF Lopez, BS Kristal, E Chernokalskaya, A Lazarev, AI Shestopalov, ... ELECTROPHORESIS: An International Journal 21 (16), 3427-3440, 2000	287	2000
The metabolomics standards initiative SA Sansone, T Fan, R Goodacre, JL Griffin, NW Hardy, ... Nature biotechnology 25 (8), 846-849, 2007	275	2007
Consensus scoring criteria for improving enrichment in virtual screening JM Yang, YF Chen, TW Shen, BS Kristal, DF Hsu Journal of chemical information and modeling 45 (4), 1134-1146, 2005	257	2005
Mitochondrial permeability transition in the central nervous system: induction by calcium cycling‐dependent and‐independent pathways BS Kristal, JM Dubinsky Journal of neurochemistry 69 (2), 524-538, 1997	255	1997
Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction ES Luth, IG Stavrovskaya, T Bartels, BS Kristal, DJ Selkoe Journal of Biological Chemistry 289 (31), 21490-21507, 2014	246	2014
Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases WJ Burke, SW Li, HD Chung, DA Ruggiero, BS Kristal, EM Johnson, ... Neurotoxicology 25 (1-2), 101-115, 2004	228	2004
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption MC Cornelis, EM Byrne, T Esko, MA Nalls, A Ganna, N Paynter, ... Molecular psychiatry 20 (5), 647-656, 2015	210	2015
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease RJ Ferrante, H Ryu, JK Kubilus, S D'Mello, KL Sugars, J Lee, P Lu, ... Journal of Neuroscience 24 (46), 10335-10342, 2004	199	2004
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase IG Gazaryan, BF Krasnikov, GA Ashby, RNF Thorneley, BS Kristal, ... Journal of Biological Chemistry 277 (12), 10064-10072, 2002	192	2002
Zn2+ inhibits α-ketoglutarate-stimulated mitochondrial respiration and the isolated α-ketoglutarate dehydrogenase complex AM Brown, BS Kristal, MS Effron, AI Shestopalov, PA Ullucci, KFR Sheu, ... Journal of Biological Chemistry 275 (18), 13441-13447, 2000	188	2000

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