Bruce S. Kristal

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Wayne Matsonchief scientist co-founder Ixcela Inc.Verified email at ixcela.com
Rima Kaddurah-DaoukProfessorVerified email at mc.duke.edu
Robert M FriedlanderUniversity of PittsburghVerified email at upmc.edu
Vasant R. MarurDiv. of Sleep & Circadian Disorders, Dept. of Medicine, Brigham and Women's Hospital, Boston, MAVerified email at bwh.harvard.edu
M. Flint BealProfessor of Neurology, Weill CornellVerified email at med.cornell.edu
Xin WangBrigham and Women's Hospital/Harvard Medical SchoolVerified email at rics.bwh.harvard.edu
Ben van OmmenPrincipal Scientist, TNOVerified email at tno.nl
Oliver FiehnUC DavisVerified email at ucdavis.edu
Rose Muthoni GathunguEuropean Biology Molecular LaboratoryVerified email at embl.de
Roy GoodacreDepartment of Biochemistry and Systems Biology, ISMIB, University of LiverpoolVerified email at liverpool.ac.uk
Lloyd W. SumnerUniversity of Missouri, Biochemistry Dept, Christopher S. Bond Life Sciences Center, MU MetabolomicsVerified email at missouri.edu
Susanna-Assunta SansoneUniversity of Oxford, Oxford e-Research Centre (Associate Director, Associate Professor)Verified email at oerc.ox.ac.uk
Pedro MendesUniversity of ConnecticutVerified email at uchc.edu
Mariët van der WerfGlobal Platform DirectorVerified email at hetnet.nl
Griffin JLUniversity of CambridgeVerified email at cam.ac.uk
Norman MorrisonResearch Fellow, School of Computer Science, University of ManchesterVerified email at manchester.ac.uk
C. Keith Ozaki, MDBrigham and Women's Hospital/Harvard Medical SchoolVerified email at partners.org
Loic Le MarchandProfessor of Epidemiology, University of Hawaii Cancer CenterVerified email at cc.hawaii.edu
James MitchellAssociate Professor of Genetics and Complex Diseases, Harvard T. H. Chan School of Public HealthVerified email at hsph.harvard.edu
Steven GullansVerified email at excelvm.com

Bruce S. Kristal

Assoc Prof, Div Sleep/Circadian Disorders, Dept Medicine, Brigham and Women's Hospital + Harvard Med

Verified email at partners.org

metabolomics lipidomics informatics biomarkers mitochondria


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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice S Zhu, IG Stavrovskaya, M Drozda, BYS Kim, V Ona, M Li, S Sarang, ... Nature 417 (6884), 74-78, 2002	1210	2002
Metabolomics: a global biochemical approach to drug response and disease R Kaddurah-Daouk, BS Kristal, RM Weinshilboum Annual review of pharmacology and toxicology 48 (1), 653-683, 2008	693	2008
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research A Scalbert, L Brennan, O Fiehn, T Hankemeier, BS Kristal, B van Ommen, ... Metabolomics 5 (4), 435-458, 2009	544	2009
Minocycline inhibits caspase-independent and-dependent mitochondrial cell death pathways in models of Huntington's disease X Wang, S Zhu, M Drozda, W Zhang, IG Stavrovskaya, E Cattaneo, ... Proceedings of the National Academy of Sciences 100 (18), 10483-10487, 2003	461	2003
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease TS Tang, E Slow, V Lupu, IG Stavrovskaya, M Sugimori, R Llinás, ... Proceedings of the National Academy of Sciences 102 (7), 2602-2607, 2005	420	2005
Proposed minimum reporting standards for data analysis in metabolomics R Goodacre, D Broadhurst, AK Smilde, BS Kristal, JD Baker, R Beger, ... Metabolomics 3 (3), 231-241, 2007	405	2007
Multiple roles of glutathione in the central nervous system GSH Generally Biol. Chem 378, 793-802, 1997	366	1997
The metabolomics standards initiative (MSI) O Fiehn, D Robertson, J Griffin, M van der Werf, B Nikolau, N Morrison, ... Metabolomics 3 (3), 175-178, 2007	345	2007
An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions BS Kristal, BP Yu Journal of Gerontology 47 (4), B107-B114, 1992	290	1992
High‐throughput profiling of the mitochondrial proteome using affinity fractionation and automation MF Lopez, BS Kristal, E Chernokalskaya, A Lazarev, AI Shestopalov, ... ELECTROPHORESIS: An International Journal 21 (16), 3427-3440, 2000	282	2000
4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition BS Kristal, BK Park, PY Byung Journal of Biological Chemistry 271 (11), 6033-6038, 1996	276	1996
Consensus scoring criteria for improving enrichment in virtual screening JM Yang, YF Chen, TW Shen, BS Kristal, DF Hsu Journal of chemical information and modeling 45 (4), 1134-1146, 2005	255	2005
Mitochondrial permeability transition in the central nervous system: induction by calcium cycling‐dependent and‐independent pathways BS Kristal, JM Dubinsky Journal of neurochemistry 69 (2), 524-538, 1997	253	1997
The metabolomics standards initiative SA Sansone, T Fan, R Goodacre, JL Griffin, NW Hardy, ... Nature biotechnology 25 (8), 846-849, 2007	246	2007
Zn2+ inhibits α-ketoglutarate-stimulated mitochondrial respiration and the isolated α-ketoglutarate dehydrogenase complex AM Brown, BS Kristal, MS Effron, AI Shestopalov, PA Ullucci, KFR Sheu, ... Journal of Biological Chemistry 275 (18), 13441-13447, 2000	231	2000
Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases WJ Burke, SW Li, HD Chung, DA Ruggiero, BS Kristal, EM Johnson, ... Neurotoxicology 25 (1-2), 101-115, 2004	216	2004
Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction ES Luth, IG Stavrovskaya, T Bartels, BS Kristal, DJ Selkoe Journal of Biological Chemistry 289 (31), 21490-21507, 2014	210	2014
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease RJ Ferrante, H Ryu, JK Kubilus, S D'Mello, KL Sugars, J Lee, P Lu, ... Journal of Neuroscience 24 (46), 10335-10342, 2004	195	2004
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase IG Gazaryan, BF Krasnikov, GA Ashby, RNF Thorneley, BS Kristal, ... Journal of Biological Chemistry 277 (12), 10064-10072, 2002	183	2002
Metabolomic analysis and signatures in motor neuron disease S Rozen, ME Cudkowicz, M Bogdanov, WR Matson, BS Kristal, ... Metabolomics 1 (2), 101-108, 2005	179	2005

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