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Andrew Holland
Andrew Holland
Associate Professor, Johns Hopkins University School of Medicine
Verified email at jhmi.edu - Homepage
Title
Cited by
Cited by
Year
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
AJ Holland, DW Cleveland
Nature reviews Molecular cell biology 10 (7), 478-487, 2009
10102009
Once and only once: mechanisms of centriole duplication and their deregulation in disease
EA Nigg, AJ Holland
Nature reviews Molecular cell biology 19 (5), 297-312, 2018
4272018
Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals
MS Levine, B Bakker, B Boeckx, J Moyett, J Lu, B Vitre, DC Spierings, ...
Developmental cell 40 (3), 313-322. e5, 2017
3552017
Losing balance: the origin and impact of aneuploidy in cancer: ‘Exploring aneuploidy: the significance of chromosomal imbalance’review series
AJ Holland, DW Cleveland
EMBO reports 13 (6), 501-514, 2012
3362012
Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells
AJ Holland, D Fachinetti, JS Han, DW Cleveland
Proceedings of the National Academy of Sciences 109 (49), E3350-E3357, 2012
3332012
Cep152 interacts with Plk4 and is required for centriole duplication
EM Hatch, A Kulukian, AJ Holland, DW Cleveland, T Stearns
Journal of Cell Biology 191 (4), 721-729, 2010
3142010
Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability
AJ Holland, W Lan, S Niessen, H Hoover, DW Cleveland
Journal of Cell Biology 188 (2), 191-198, 2010
2972010
Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements
AJ Holland, DW Cleveland
Nature medicine 18 (11), 1630-1638, 2012
2872012
A two-step mechanism for epigenetic specification of centromere identity and function
D Fachinetti, H Diego Folco, Y Nechemia-Arbely, LP Valente, K Nguyen, ...
Nature cell biology 15 (9), 1056-1066, 2013
2782013
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
AD Silk, LM Zasadil, AJ Holland, B Vitre, DW Cleveland, BA Weaver
Proceedings of the National Academy of Sciences 110 (44), E4134-E4141, 2013
2732013
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E
Y Kim, AJ Holland, W Lan, DW Cleveland
Cell 142 (3), 444-455, 2010
2732010
The impact of mitotic errors on cell proliferation and tumorigenesis
MS Levine, AJ Holland
Genes & development 32 (9-10), 620-638, 2018
2252018
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells
R Gassmann, AJ Holland, D Varma, X Wan, F Çivril, DW Cleveland, ...
Genes & development 24 (9), 957-971, 2010
2202010
Binding of STIL to Plk4 activates kinase activity to promote centriole assembly
TC Moyer, KM Clutario, BG Lambrus, V Daggubati, AJ Holland
Journal of Cell Biology 209 (6), 863-878, 2015
2112015
A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis
BG Lambrus, V Daggubati, Y Uetake, PM Scott, KM Clutario, G Sluder, ...
Journal of Cell Biology 214 (2), 143-153, 2016
2052016
The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation
SS Taylor, MIF Scott, AJ Holland
Chromosome Research 12, 599-616, 2004
1912004
Mechanism and regulation of centriole and cilium biogenesis
DK Breslow, AJ Holland
Annual review of biochemistry 88, 691-724, 2019
1852019
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle
AJ Holland, D Fachinetti, Q Zhu, M Bauer, IM Verma, EA Nigg, ...
Genes & development 26 (24), 2684-2689, 2012
1702012
Requirements for NuMA in maintenance and establishment of mammalian spindle poles
AD Silk, AJ Holland, DW Cleveland
Journal of cell biology 184 (5), 677-690, 2009
1542009
p53 protects against genome instability following centriole duplication failure
BG Lambrus, Y Uetake, KM Clutario, V Daggubati, M Snyder, G Sluder, ...
Journal of Cell Biology 210 (1), 63-77, 2015
1522015
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