Oxidative stress and lipid peroxidation are upstream of amyloid pathology M Arimon, S Takeda, KL Post, S Svirsky, BT Hyman, O Berezovska Neurobiology of disease 84, 109-119, 2015 | 146 | 2015 |
Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease L Wahlster, M Arimon, N Nasser-Ghodsi, KL Post, A Serrano-Pozo, ... Acta neuropathologica 125, 187-199, 2013 | 75 | 2013 |
Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease AR Winslow, S Moussaud, L Zhu, KL Post, DW Dickson, O Berezovska, ... Brain 137 (7), 1958-1970, 2014 | 61 | 2014 |
Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction KL Post, M Belmadani, P Ganguly, F Meili, R Dingwall, TA McDiarmid, ... Nature communications 11 (1), 2073, 2020 | 43 | 2020 |
Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta A Kuzuya, KM Zoltowska, KL Post, M Arimon, X Li, S Svirsky, M Maesako, ... BMC biology 14, 1-24, 2016 | 43 | 2016 |
Sentinel interaction mapping–a generic approach for the functional analysis of human disease gene variants using yeast BP Young, KL Post, JT Chao, F Meili, K Haas, C Loewen Disease models & mechanisms 13 (7), dmm044560, 2020 | 5 | 2020 |
RPGRIP1 Landscape Analysis and Clinical Development Report M Grant, K Post, AR Winslow Odylia Therapeutics, 2-2, 2020 | | 2020 |
Impact of Autism Spectrum Disorder associated PTEN point mutations on protein function and stability KL Post University of British Columbia, 2019 | | 2019 |
CLOVES Syndrome Gap and Landscape Analysis K Post, F Atkinson, AR Winslow Odylia Therapeutics. 2021; Available at https://odylia. org/wp-content …, 0 | | |
Multi-Model Functionalization of 106 PTEN Missense Mutations Identifies Multiple Molecular Mechanisms Underlying Protein Dysfunction K Post, M Belmadani, P Ganguly, F Meili, R Dingwall, TA McDiarmid, ... INSAR 2020 Virtual Meeting, 0 | | |