| Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat JJ Lu, K Crimin, JT Goodwin, P Crivori, C Orrenius, L Xing, PJ Tandler, ... Journal of medicinal chemistry 47 (24), 6104-6107, 2004 | 198 | 2004 |
| Template-directed synthesis: use of a reversible reaction JT Goodwin, DG Lynn Journal of the American Chemical Society 114 (23), 9197-9198, 1992 | 179 | 1992 |
| In silico predictions of blood-brain barrier penetration: considerations to “keep in mind” JT Goodwin, DE Clark Journal of Pharmacology and Experimental Therapeutics 315 (2), 477-483, 2005 | 146 | 2005 |
| Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume JT Goodwin, RA Conradi, NFH Ho, PS Burton Journal of medicinal chemistry 44 (22), 3721-3729, 2001 | 135 | 2001 |
| Predicting drug absorption: how nature made it a difficult problem PS Burton, JT Goodwin, TJ Vidmar, BM Amore Journal of Pharmacology and Experimental Therapeutics 303 (3), 889-895, 2002 | 125 | 2002 |
| Characterization of the Fusarium toxin equisetin: the use of phenylboronates in structure assignment NJ Phillips, JT Goodwin, A Fraiman, RJ Cole, DG Lynn Journal of the American Chemical Society 111 (21), 8223-8231, 1989 | 111 | 1989 |
| Incorporation of alkylthiol chains at C-5 of deoxyuridine JT Goodwin, GD Glick Tetrahedron letters 34 (35), 5549-5552, 1993 | 69 | 1993 |
| Design of multi-phase dynamic chemical networks C Chen, J Tan, MC Hsieh, T Pan, JT Goodwin, AK Mehta, MA Grover, ... Nature Chemistry 9 (8), 799-804, 2017 | 64 | 2017 |
| Design, Synthesis, and Analysis of Yeast tRNAPhe Analogs Possessing Intra- and Interhelical Disulfide Cross-Links JT Goodwin, SE Osborne, EJ Scholle, GD Glick Journal of the American Chemical Society 118 (22), 5207-5215, 1996 | 60 | 1996 |
| Digital and analog chemical evolution JT Goodwin, AK Mehta, DG Lynn Accounts of chemical research 45 (12), 2189-2199, 2012 | 52 | 2012 |
| Synthesis of a disulfide stabilized RNA hairpin JT Goodwin, GD Glick Tetrahedron letters 35 (11), 1647-1650, 1994 | 52 | 1994 |
| Strategies toward predicting peptide cellular permeability from computed molecular descriptors JT Goodwin, RA Conradi, PS Burton, B Mao, TJ Vidmar The Journal of peptide research 53 (4), 355-369, 1999 | 49 | 1999 |
| In vitro permeability of peptidomimetic drugs: The role of polarized efflux pathways as additional barriers to absorption PS Burton, JT Goodwin, RA Conradi, NFH Ho, AR Hilgers Advanced drug delivery reviews 23 (1-3), 143-156, 1997 | 42 | 1997 |
| One among millions: The chemical space of nucleic acid-like molecules HJ Cleaves, C Butch, PB Burger, J Goodwin, M Meringer Journal of Chemical Information and Modeling 59 (10), 4266-4277, 2019 | 34 | 2019 |
| 227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space? HJII Cleaves, M Meringer, J Goodwin Astrobiology 15 (7), 538-558, 2015 | 29 | 2015 |
| Synthesis of a disulfide cross-linked DNA triple helix JT Goodwin, SE Osborne, PC Swanson, GD Glick Tetrahedron letters 35 (26), 4527-4530, 1994 | 23 | 1994 |
| Improved solid-phase synthesis of long oligoribonucleotides: application to tRNAPhe and tRNAGly JT Goodwin, WA Stanick, GD Glick The Journal of Organic Chemistry 59 (26), 7941-7943, 1994 | 22 | 1994 |
| Probing the structure of an RNA tertiary unfolding transition state EJ Maglott, JT Goodwin, GD Glick Journal of the American Chemical Society 121 (32), 7461-7462, 1999 | 21 | 1999 |
| Expanding the informational chemistries of life: peptide/RNA networks O Taran, C Chen, TO Omosun, MC Hsieh, A Rha, JT Goodwin, AK Mehta, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2017 | 20 | 2017 |
| Solubility and permeability measurement and applications in drug discovery PS Burton, JT Goodwin Combinatorial chemistry & high throughput screening 13 (2), 101-111, 2010 | 18 | 2010 |
David LynnProfessor of Chemistry and Biology, Emory UniversityBestätigte E-Mail-Adresse bei emory.edu
