Insights into metalloenzyme microenvironments: biomimetic metal complexes with a functional second coordination sphere M Zhao, HB Wang, LN Ji, ZW Mao Chemical Society Reviews 42 (21), 8360-8375, 2013 | 219 | 2013 |
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance H Wang, M Wang, X Xu, P Gao, Z Xu, Q Zhang, H Li, A Yan, RYT Kao, ... Nature communications 12 (1), 3331, 2021 | 111 | 2021 |
Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli H Wang, A Yan, Z Liu, X Yang, Z Xu, Y Wang, R Wang, ... PLoS biology 17 (6), e3000292, 2019 | 89 | 2019 |
Resensitizing carbapenem-and colistin-resistant bacteria to antibiotics using auranofin H Sun, Q Zhang, R Wang, H Wang, YT Wong, M Wang, Q Hao, A Yan, ... Nature communications 11 (1), 5263, 2020 | 87 | 2020 |
Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli Z Xu, P Wang, H Wang, ZH Yu, HY Au-Yeung, T Hirayama, H Sun, A Yan Journal of Biological Chemistry 294 (45), 16978-16991, 2019 | 67 | 2019 |
Combination of gallium (iii) with acetate for combating antibiotic resistant Pseudomonas aeruginosa Y Wang, B Han, Y Xie, H Wang, R Wang, W Xia, H Li, H Sun Chemical science 10 (24), 6099-6106, 2019 | 60 | 2019 |
Predicting disease-associated mutation of metal-binding sites in proteins using a deep learning approach M Koohi-Moghadam, H Wang, Y Wang, X Yang, H Li, J Wang, H Sun Nature Machine Intelligence 1 (12), 561-567, 2019 | 54 | 2019 |
Metalloproteomics in conjunction with other omics for uncovering the mechanism of action of metallodrugs: mechanism-driven new therapy development H Wang, Y Zhou, X Xu, H Li, H Sun Current opinion in chemical biology 55, 171-179, 2020 | 53 | 2020 |
Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli H Wang, M Wang, X Yang, X Xu, Q Hao, A Yan, M Hu, R Lobinski, H Li, ... Chemical science 10 (30), 7193-7199, 2019 | 49 | 2019 |
Metallomic and metalloproteomic strategies in elucidating the molecular mechanisms of metallodrugs Y Wang, H Wang, H Li, H Sun Dalton Transactions 44 (2), 437-447, 2015 | 45 | 2015 |
Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment B Han, Z Zhang, Y Xie, X Hu, H Wang, W Xia, Y Wang, H Li, Y Wang, ... Chemical science 9 (38), 7488-7497, 2018 | 35 | 2018 |
Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin X Hu, H Li, TKY Ip, YF Cheung, M Koohi-Moghadam, H Wang, X Yang, ... Chemical Science 12 (32), 10893-10900, 2021 | 29 | 2021 |
Cell cycle-dependent uptake and cytotoxicity of arsenic-based drugs in single leukemia cells Y Zhou, H Wang, E Tse, H Li, H Sun Analytical chemistry 90 (17), 10465-10471, 2018 | 28 | 2018 |
Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver Q Zhang, R Wang, M Wang, C Liu, M Koohi-Moghadam, H Wang, PL Ho, ... Proceedings of the National Academy of Sciences 119 (11), e2119417119, 2022 | 24 | 2022 |
S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3. 3, leading to TRAIL-induced apoptosis in leukemia cells X Xu, H Wang, H Li, X Hu, Y Zhang, X Guan, PH Toy, H Sun Chemical Communications 55 (87), 13120-13123, 2019 | 22 | 2019 |
Metalloproteomic approaches for matching metals to proteins: the power of inductively coupled plasma mass spectrometry (ICP-MS) X Xu, H Wang, H Li, H Sun Chemistry Letters 49 (6), 697-704, 2020 | 18 | 2020 |
Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm H Wang, X Yang, M Wang, M Hu, X Xu, A Yan, Q Hao, H Li, H Sun Chemical Science 11 (43), 11714-11719, 2020 | 15 | 2020 |
Mitochondrial ATP synthase as a direct molecular target of chromium (III) to ameliorate hyperglycaemia stress H Wang, L Hu, H Li, YT Lai, X Wei, X Xu, Z Cao, H Cao, Q Wan, YY Chang, ... Nature Communications 14 (1), 1738, 2023 | 14 | 2023 |
Selective interaction of Hpn-like protein with nickel, zinc and bismuth in vitro and in cells by FRET YY Chang, YT Lai, T Cheng, H Wang, Y Yang, H Sun Journal of Inorganic Biochemistry 142, 8-14, 2015 | 11 | 2015 |
Binding of ruthenium and osmium at non‑iron sites of transferrin accounts for their iron-independent cellular uptake M Wang, H Wang, X Xu, TP Lai, Y Zhou, Q Hao, H Li, H Sun Journal of Inorganic Biochemistry 234, 111885, 2022 | 7 | 2022 |