Florian Grebien
Florian Grebien
Institute for Medical Biochemistry - University of Veterinary Medicine Vienna
Bestätigte E-Mail-Adresse bei vetmeduni.ac.at
TitelZitiert vonJahr
Stat5 is indispensable for the maintenance of bcr/abl‐positive leukaemia
A Hoelbl, C Schuster, B Kovacic, B Zhu, M Wickre, MA Hoelzl, S Fajmann, ...
EMBO molecular medicine 2 (3), 98-110, 2010
2172010
Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation
P Filippakopoulos, M Kofler, O Hantschel, GD Gish, F Grebien, E Salah, ...
Cell 134 (5), 793-803, 2008
1812008
CD14 is a coreceptor of Toll-like receptors 7 and 9
CL Baumann, IM Aspalter, O Sharif, A Pichlmair, S Blüml, F Grebien, ...
Journal of Experimental Medicine 207 (12), 2689-2701, 2010
1712010
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
O Hantschel, W Warsch, E Eckelhart, I Kaupe, F Grebien, KU Wagner, ...
Nature chemical biology 8 (3), 285, 2012
1542012
Evidence for a size-sensing mechanism in animal cells
H Dolznig, F Grebien, T Sauer, H Beug, EW Müllner
Nature cell biology 6 (9), 899, 2004
1382004
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain
J Wojcik, O Hantschel, F Grebien, I Kaupe, KL Bennett, J Barkinge, ...
Nature structural & molecular biology 17 (4), 519, 2010
1322010
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis
F Grebien, O Hantschel, J Wojcik, I Kaupe, B Kovacic, AM Wyrzucki, ...
Cell 147 (2), 306-319, 2011
1072011
Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1
MA Kerenyi, F Grebien, H Gehart, M Schifrer, M Artaker, B Kovacic, ...
Blood 112 (9), 3878-3888, 2008
1032008
Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2
F Grebien, MA Kerenyi, B Kovacic, T Kolbe, V Becker, H Dolznig, K Pfeffer, ...
Blood 111 (9), 4511-4522, 2008
992008
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ...
Nature chemical biology 11 (8), 571, 2015
972015
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
GE Winter, U Rix, SM Carlson, KV Gleixner, F Grebien, M Gridling, ...
Nature chemical biology 8 (11), 905, 2012
892012
STAT3 regulated ARF expression suppresses prostate cancer metastasis
J Pencik, M Schlederer, W Gruber, C Unger, SM Walker, A Chalaris, ...
Nature communications 6, 7736, 2015
832015
Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR
H Dolznig, F Grebien, EM Deiner, K Stangl, A Kolbus, B Habermann, ...
Oncogene 25 (20), 2890, 2006
692006
The growing arsenal of ATP-competitive and allosteric inhibitors of BCR–ABL
O Hantschel, F Grebien, G Superti-Furga
Cancer research 72 (19), 4890-4895, 2012
652012
JAK-STAT signaling in cancer: From cytokines to non-coding genome
J Pencik, HTT Pham, J Schmoellerl, T Javaheri, M Schlederer, Z Culig, ...
Cytokine 87, 26-36, 2016
552016
Nilotinib exerts direct pro-atherogenic and anti-angiogenic effects on vascular endothelial cells: a potential explanation for drug-induced vasculopathy in CML
K Albrecht-Schgoer, K Huber, F Grebien, G Eisenwort, W Schgoer, ...
Blood 122 (21), 257-257, 2013
482013
The different functions of Stat5 and chromatin alteration through Stat5 proteins
JW Kornfeld, F Grebien, MA Kerenyi, K Friedbichler, B Kovacic, B Zankl, ...
Frontiers in bioscience: a journal and virtual library 13, 6237, 2008
472008
Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer
EB Haura, A Müller, FP Breitwieser, J Li, F Grebien, J Colinge, ...
Journal of proteome research 10 (1), 182-190, 2010
372010
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
J Li, K Bennett, A Stukalov, B Fang, G Zhang, T Yoshida, I Okamoto, ...
Molecular systems biology 9 (1), 2013
352013
Cell size control: new evidence for a general mechanism
F Grebien, H Dolznig, H Beug, EW Müllner
Cell Cycle 4 (3), 418-421, 2005
322005
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