Principal components analysis corrects for stratification in genome-wide association studies AL Price, NJ Patterson, RM Plenge, ME Weinblatt, NA Shadick, D Reich Nature genetics 38 (8), 904-909, 2006 | 9647 | 2006 |
Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 1960 | 2014 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010 | 1425 | 2010 |
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007 | 1207 | 2007 |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation International HIV Controllers Study Science 330 (6010), 1551-1557, 2010 | 994 | 2010 |
TRAF1–C5 as a risk locus for rheumatoid arthritis—a genomewide study RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, ... New England Journal of Medicine 357 (12), 1199-1209, 2007 | 989 | 2007 |
JAK and STAT signaling molecules in immunoregulation and immune-mediated disease JJ O'Shea, R Plenge Immunity 36 (4), 542-550, 2012 | 929 | 2012 |
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis S Raychaudhuri, C Sandor, EA Stahl, J Freudenberg, HS Lee, X Jia, ... Nature genetics 44 (3), 291-296, 2012 | 879 | 2012 |
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, ... Nature genetics 45 (2), 145-154, 2013 | 738 | 2013 |
Genomic atlas of the human plasma proteome BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley, J Blackshaw, ... Nature 558 (7708), 73-79, 2018 | 733 | 2018 |
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus RR Graham, SV Kozyrev, EC Baechler, MV Reddy, RM Plenge, JW Bauer, ... Nature genetics 38 (5), 550-555, 2006 | 695 | 2006 |
Defining the role of the MHC in autoimmunity: a review and pooled analysis MMA Fernando, CR Stevens, EC Walsh, PL De Jager, P Goyette, ... PLoS genetics 4 (4), e1000024, 2008 | 687 | 2008 |
Replication of putative candidate-gene associations with rheumatoid arthritis in> 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4 … RM Plenge, L Padyukov, EF Remmers, S Purcell, AT Lee, EW Karlson, ... American journal of human genetics 77 (6), 1044, 2005 | 682 | 2005 |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 655 | 2012 |
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis RM Plenge, C Cotsapas, L Davies, AL Price, PIW De Bakker, J Maller, ... Nature genetics 39 (12), 1477-1482, 2007 | 641 | 2007 |
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus RR Graham, C Cotsapas, L Davies, R Hackett, CJ Lessard, JM Leon, ... Nature genetics 40 (9), 1059-1061, 2008 | 612 | 2008 |
de VN, Worthington J, Seielstad M, Toes RE, Karlson EW, Begovich AB, Klareskog L, Gregersen PK, Daly MJ, Plenge RM: Common variants at CD40 and other loci confer risk of … S Raychaudhuri, EF Remmers, AT Lee, R Hackett, C Guiducci, NP Burtt, ... Nat Genet 40, 1216-1223, 2008 | 583* | 2008 |
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis H Källberg, L Padyukov, RM Plenge, J Rönnelid, PK Gregersen, ... American journal of human genetics 80 (5), 867, 2007 | 557 | 2007 |
Validating therapeutic targets through human genetics RM Plenge, EM Scolnick, D Altshuler Nature reviews Drug discovery 12 (8), 581-594, 2013 | 528 | 2013 |
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus RR Graham, C Kyogoku, S Sigurdsson, IA Vlasova, LRL Davies, ... Proceedings of the National Academy of Sciences 104 (16), 6758-6763, 2007 | 527 | 2007 |