Chris Bakal
Chris Bakal
Team Leader, Chester Beatty Laboratories, Institute of Cancer Research
Verified email at - Homepage
Cited by
Cited by
The MAGUK family protein CARD11 is essential for lymphocyte activation
H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ...
Immunity 18 (6), 763-775, 2003
Quantitative morphological signatures define local signaling networks regulating cell morphology
C Bakal, J Aach, G Church, N Perrimon
science 316 (5832), 1753-1756, 2007
Genomic screening with RNAi: results and challenges
S Mohr, C Bakal, N Perrimon
Annual review of biochemistry 79, 37-64, 2010
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ...
Nature communications 8 (1), 14728, 2017
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ...
Clinical Cancer Research 23 (18), 5561-5572, 2017
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ...
Nature cell biology 15 (7), 860-871, 2013
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ...
The Journal of experimental medicine 199 (3), 399-410, 2004
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions
PM Müller, J Rademacher, RD Bagshaw, C Wortmann, C Barth, ...
Nature cell biology 22 (4), 498-511, 2020
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds
C Bakal, R Linding, F Llense, E Heffern, E Martin-Blanco, T Pawson, ...
science 322 (5900), 453-456, 2008
Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells
JE Sero, HZ Sailem, RC Ardy, H Almuttaqi, T Zhang, C Bakal
Molecular systems biology 11 (3), 790, 2015
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis
R Natrajan, H Sailem, FK Mardakheh, M Arias Garcia, CJ Tape, ...
PLoS medicine 13 (2), e1001961, 2016
A dynamical framework for the all-or-none G1/S transition
AR Barr, FS Heldt, T Zhang, C Bakal, B Novák
Cell systems 2 (1), 27-37, 2016
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
L Stojic, ATL Lun, J Mangei, P Mascalchi, V Quarantotti, AR Barr, C Bakal, ...
Nucleic acids research 46 (12), 5950-5966, 2018
Nanoneedle-mediated stimulation of cell mechanotransduction machinery
CS Hansel, SW Crowder, S Cooper, S Gopal, M Joăo Pardelha da Cruz, ...
ACS nano 13 (3), 2913-2926, 2019
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition
D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ...
Molecular cell 45 (5), 642-655, 2012
A comprehensive model for the proliferation–quiescence decision in response to endogenous DNA damage in human cells
FS Heldt, AR Barr, S Cooper, C Bakal, B Novák
Proceedings of the National Academy of Sciences 115 (10), 2532-2537, 2018
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
H Sailem, V Bousgouni, S Cooper, C Bakal
Open biology 4 (1), 130132, 2014
Multiparametric analysis of cell shape demonstrates that β-PIX directly couples YAP activation to extracellular matrix adhesion
JE Sero, C Bakal
Cell systems 4 (1), 84-96. e6, 2017
The twin spot generator for differential Drosophila lineage analysis
R Griffin, A Sustar, M Bonvin, R Binari, A del Valle Rodriguez, AM Hohl, ...
Nature methods 6 (8), 600-602, 2009
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens
Z Yin, X Zhou, C Bakal, F Li, Y Sun, N Perrimon, STC Wong
BMC bioinformatics 9 (1), 1-20, 2008
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