Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals PM Quirós, MA Prado, N Zamboni, D D’Amico, RW Williams, D Finley, ... Journal of Cell Biology 216 (7), 2027-2045, 2017 | 673 | 2017 |
USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites BH Lee, Y Lu, MA Prado, Y Shi, G Tian, S Sun, S Elsasser, SP Gygi, ... Nature 532 (7599), 398-401, 2016 | 188 | 2016 |
Highly multiplexed quantitative mass spectrometry analysis of ubiquitylomes CM Rose, M Isasa, A Ordureau, MA Prado, SA Beausoleil, ... Cell systems 3 (4), 395-403. e4, 2016 | 167 | 2016 |
UBE2O remodels the proteome during terminal erythroid differentiation AT Nguyen, MA Prado, PJ Schmidt, AK Sendamarai, JT Wilson-Grady, ... Science 357 (6350), eaan0218, 2017 | 130 | 2017 |
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons M Boselli, BH Lee, J Robert, MA Prado, SW Min, C Cheng, MC Silva, ... Journal of Biological Chemistry 292 (47), 19209-19225, 2017 | 111 | 2017 |
TRAF-mediated modulation of NF-kB AND JNK activation by TNFR2 L Cabal-Hierro, M Rodríguez, N Artime, J Iglesias, L Ugarte, MA Prado, ... Cellular signalling 26 (12), 2658-2666, 2014 | 81 | 2014 |
ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function JJ Wu, A Cai, JE Greenslade, NR Higgins, C Fan, NTT Le, M Tatman, ... Proceedings of the National Academy of Sciences 117 (26), 15230-15241, 2020 | 67 | 2020 |
Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia G Bretones, MG Álvarez, JR Arango, D Rodríguez, F Nadeu, MA Prado, ... Blood, The Journal of the American Society of Hematology 132 (22), 2375-2388, 2018 | 67 | 2018 |
The proteasome and its network: Engineering for adaptability D Finley, MA Prado Cold Spring Harbor perspectives in biology 12 (1), a033985, 2020 | 55 | 2020 |
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity L Cabal-Hierro, P van Galen, MA Prado, KJ Higby, K Togami, CT Mowery, ... Nature communications 11 (1), 1406, 2020 | 49 | 2020 |
Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins AM Whiteley, MA Prado, I Peng, AR Abbas, B Haley, JA Paulo, M Reichelt, ... Elife 6, e26435, 2017 | 41 | 2017 |
Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice JM Fraile, D Campos-Iglesias, F Rodríguez, A Astudillo, R Vilarrasa-Blasi, ... Journal of Biological Chemistry 293 (6), 2183-2194, 2018 | 35 | 2018 |
A TRAF2 binding independent region of TNFR2 is responsibl for TRAF2 depletion and enhancement of cytotoxicity driven b TNFR1 L Cabal-Hierro, A Noelia, J Iglesias, L Ugarte-Gil, C Pedro, ... Oncotarget 5 (1), 224, 2014 | 32 | 2014 |
The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling F Massa, R Tammaro, MA Prado, M Cesana, BH Lee, D Finley, B Franco, ... Human Molecular Genetics 28 (5), 764-777, 2019 | 29 | 2019 |
Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis HM Schnell, RM Walsh Jr, S Rawson, M Kaur, MK Bhanu, G Tian, ... Nature structural & molecular biology 28 (5), 418-425, 2021 | 25 | 2021 |
Global proteomics of Ubqln2-based murine models of ALS AM Whiteley, MA Prado, SAH de Poot, JA Paulo, M Ashton, S Dominguez, ... Journal of Biological Chemistry 296, 2021 | 24 | 2021 |
Maternal iron deficiency modulates placental transcriptome and proteome in mid-gestation of mouse pregnancy C Cao, MA Prado, L Sun, S Rockowitz, P Sliz, JA Paulo, D Finley, ... The Journal of nutrition 151 (5), 1073-1083, 2021 | 18 | 2021 |
Characterization of HSP27 phosphorylation induced by microtubule interfering agents: Implication of p38 signalling pathway P Casado, P Zuazua-Villar, MA Prado, E Del Valle, JM Iglesias, ... Archives of biochemistry and biophysics 461 (1), 123-129, 2007 | 15 | 2007 |
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice HAB Paterson, S Yu, N Artigas, MA Prado, N Haberman, YF Wang, ... Nature Metabolism 4 (12), 1812-1829, 2022 | 14 | 2022 |
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import BC Lin, TH Phung, NR Higgins, JE Greenslade, MA Prado, D Finley, ... Human Molecular Genetics 30 (13), 1230-1246, 2021 | 14 | 2021 |