Jonathan C Kagan
Jonathan C Kagan
Harvard Medical School/Boston Children's Hospital
Verified email at - Homepage
Cited by
Cited by
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
JC Kagan, T Su, T Horng, A Chow, S Akira, R Medzhitov
Nature immunology 9 (4), 361-368, 2008
Innate immune pattern recognition: a cell biological perspective
SW Brubaker, KS Bonham, I Zanoni, JC Kagan
Annual review of immunology 33, 257-290, 2015
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
JC Kagan, R Medzhitov
Cell 125 (5), 943-955, 2006
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
GM Barton, JC Kagan, R Medzhitov
Nature immunology 7 (1), 49-56, 2006
A cell biological view of Toll-like receptor function: regulation through compartmentalization
GM Barton, JC Kagan
Nature Reviews Immunology 9 (8), 535-542, 2009
CD14 controls the LPS-induced endocytosis of Toll-like receptor 4
I Zanoni, R Ostuni, LR Marek, S Barresi, R Barbalat, GM Barton, ...
Cell 147 (4), 868-880, 2011
Peroxisomes are signaling platforms for antiviral innate immunity
E Dixit, S Boulant, Y Zhang, ASY Lee, C Odendall, B Shum, N Hacohen, ...
Cell 141 (4), 668-681, 2010
A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes
H Nagai, JC Kagan, X Zhu, RA Kahn, CR Roy
Science 295 (5555), 679-682, 2002
Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites
JC Kagan, CR Roy
Nature cell biology 4 (12), 945-954, 2002
The pore-forming protein gasdermin D regulates interleukin-1 secretion from living macrophages
CL Evavold, J Ruan, Y Tan, S Xia, H Wu, JC Kagan
Immunity 48 (1), 35-44. e6, 2018
Legionella Subvert the Functions of Rab1 and Sec22b to Create a Replicative Organelle
JC Kagan, MP Stein, M Pypaert, CR Roy
The Journal of experimental medicine 199 (9), 1201-1211, 2004
A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells
H Nagai, ED Cambronne, JC Kagan, JC Amor, RA Kahn, CR Roy
Proceedings of the National Academy of Sciences 102 (3), 826-831, 2005
Diverse intracellular pathogens activate type III interferon expression from peroxisomes
C Odendall, E Dixit, F Stavru, H Bierne, KM Franz, AF Durbin, S Boulant, ...
Nature immunology 15 (8), 717-726, 2014
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
I Zanoni, Y Tan, M Di Gioia, A Broggi, J Ruan, J Shi, CA Donado, F Shao, ...
Science 352 (6290), 1232-1236, 2016
Toll-like receptors and the control of immunity
KA Fitzgerald, JC Kagan
Cell 180 (6), 1044-1066, 2020
A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction
KS Bonham, MH Orzalli, K Hayashi, AI Wolf, C Glanemann, W Weninger, ...
Cell 156 (4), 705-716, 2014
Early innate immune responses to bacterial LPS
CV Rosadini, JC Kagan
Current opinion in immunology 44, 14-19, 2017
Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth
J Coers, JC Kagan, M Matthews, H Nagai, DM Zuckman, CR Roy
Molecular microbiology 38 (4), 719-736, 2000
Intracellular pathogen detection by RIG-I-like receptors
E Dixit, JC Kagan
Advances in immunology 117, 99-125, 2013
A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide
Y Tan, JC Kagan
Molecular cell 54 (2), 212-223, 2014
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