Stat5 is indispensable for the maintenance of bcr/abl‐positive leukaemia A Hoelbl, C Schuster, B Kovacic, B Zhu, M Wickre, MA Hoelzl, S Fajmann, ... EMBO molecular medicine 2 (3), 98-110, 2010 | 303 | 2010 |
Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation A Hoelbl, B Kovacic, MA Kerenyi, O Simma, W Warsch, Y Cui, H Beug, ... Blood 107 (12), 4898-4906, 2006 | 268 | 2006 |
High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia W Warsch, K Kollmann, E Eckelhart, S Fajmann, S Cerny-Reiterer, ... Blood, The Journal of the American Society of Hematology 117 (12), 3409-3420, 2011 | 237 | 2011 |
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation R Scheicher, A Hoelbl-Kovacic, F Bellutti, AS Tigan, M Prchal-Murphy, ... Blood, The Journal of the American Society of Hematology 125 (1), 90-101, 2015 | 202 | 2015 |
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy E Porpaczy, S Tripolt, A Hoelbl-Kovacic, B Gisslinger, Z Bago-Horvath, ... Blood, The Journal of the American Society of Hematology 132 (7), 694-706, 2018 | 151 | 2018 |
Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic … M Shehata, S Schnabl, D Demirtas, M Hilgarth, R Hubmann, E Ponath, ... Blood, The Journal of the American Society of Hematology 116 (14), 2513-2521, 2010 | 131 | 2010 |
Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2 M Duechler, M Shehata, JD Schwarzmeier, A Hoelbl, M Hilgarth, ... Leukemia 19 (2), 260-267, 2005 | 94 | 2005 |
STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia W Warsch, E Grundschober, A Berger, L Gille, S Cerny-Reiterer, AS Tigan, ... Oncotarget 3 (12), 1669, 2012 | 92 | 2012 |
Unique effects of KIT D816V in BaF3 cells: induction of cluster formation, histamine synthesis, and early mast cell differentiation antigens M Mayerhofer, KV Gleixner, A Hoelbl, S Florian, G Hoermann, ... The Journal of Immunology 180 (8), 5466-5476, 2008 | 87 | 2008 |
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation K Friedbichler, MA Kerenyi, B Kovacic, G Li, A Hoelbl, S Yahiaoui, V Sexl, ... Blood, The Journal of the American Society of Hematology 116 (9), 1548-1558, 2010 | 79 | 2010 |
Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML I Sadovnik, A Hoelbl-Kovacic, H Herrmann, G Eisenwort, S Cerny-Reiterer, ... Clinical Cancer Research 22 (8), 2051-2061, 2016 | 69 | 2016 |
PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis A Berger, A Hoelbl-Kovacic, J Bourgeais, L Hoefling, W Warsch, ... Leukemia 28 (3), 629-641, 2014 | 66 | 2014 |
The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor A Ecker, O Simma, A Hoelbl, L Kenner, H Beug, R Moriggl, V Sexl Front Biosci 14 (1), 2944-2958, 2009 | 63 | 2009 |
STAT5A and STAT5B—twins with different personalities in hematopoiesis and leukemia B Maurer, S Kollmann, J Pickem, A Hoelbl-Kovacic, V Sexl Cancers 11 (11), 1726, 2019 | 56 | 2019 |
The different functions of Stat5 and chromatin alteration through Stat5 proteins JW Kornfeld, F Grebien, MA Kerenyi, K Friedbichler, B Kovacic, B Zankl, ... Frontiers in bioscience: a journal and virtual library 13, 6237, 2008 | 55 | 2008 |
Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia S Kollmann, E Grundschober, B Maurer, W Warsch, R Grausenburger, ... Leukemia 33 (7), 1583-1597, 2019 | 54 | 2019 |
Opioids: modulators of angiogenesis in wound healing and cancer M Ondrovics, A Hoelbl-Kovacic, DA Fux Oncotarget 8 (15), 25783, 2017 | 46 | 2017 |
The cooperating mutation or “second hit” determines the immunologic visibility toward MYC-induced murine lymphomas C Schuster, A Berger, MA Hoelzl, EM Putz, A Frenzel, O Simma, N Moritz, ... Blood, The Journal of the American Society of Hematology 118 (17), 4635-4645, 2011 | 46 | 2011 |
c-JUN promotes BCR-ABL–induced lymphoid leukemia by inhibiting methylation of the 5′ region of Cdk6 K Kollmann, G Heller, RG Ott, R Scheicher, E Zebedin-Brandl, ... Blood, The Journal of the American Society of Hematology 117 (15), 4065-4075, 2011 | 43 | 2011 |
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia B Maurer, H Nivarthi, B Wingelhofer, HTT Pham, M Schlederer, T Suske, ... Haematologica 105 (2), 435, 2020 | 42 | 2020 |